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- Aberrant_crypt_foci abstract "Aberrant crypt foci (ACF) are clusters of abnormal tube-like glands in the lining of the colon and rectum. Aberrant crypt foci form before colorectal polyps and are one of the earliest changes seen in the colon that may lead to cancer. ACF are, as opposed to normal epithelial cells, apoptosis resistant. When looking for aberrant crypt foci with microscopy, methylene blue is used as a staining agent. The resulting figure is fairly easy to detect under the microscope at low magnification (x40).Chemically induced ACF in rodents have been used extensively to test chemicals and diets that might prevent colorectal cancer, and reported in more than 400 scientific articles. The \"chemoprevention database\" shows the results of all published scientific studies of chemopreventive agents, in people and in animals.The relevance of ACF as a surrogate endpoint biomarker for cancer is controversial. Recently, several alternative precancerous lesions have been described (namely MDF, BCAC, and flat ACF), which might be better biomarkers than ACF.Resveratrol glucoside from transgenic alfalfa has been used for the prevention of aberrant crypt foci in mice.".
- Aberrant_crypt_foci wikiPageID "20821889".
- Aberrant_crypt_foci wikiPageLength "2707".
- Aberrant_crypt_foci wikiPageOutDegree "10".
- Aberrant_crypt_foci wikiPageRevisionID "589918522".
- Aberrant_crypt_foci wikiPageWikiLink Apoptosis.
- Aberrant_crypt_foci wikiPageWikiLink Cancer.
- Aberrant_crypt_foci wikiPageWikiLink Category:Digestive_system_neoplasia.
- Aberrant_crypt_foci wikiPageWikiLink Category:Pathology.
- Aberrant_crypt_foci wikiPageWikiLink Colorectal_polyp.
- Aberrant_crypt_foci wikiPageWikiLink Large_intestine.
- Aberrant_crypt_foci wikiPageWikiLink Methylene_blue.
- Aberrant_crypt_foci wikiPageWikiLink Piceid.
- Aberrant_crypt_foci wikiPageWikiLink Rectum.
- Aberrant_crypt_foci wikiPageWikiLink Staining.
- Aberrant_crypt_foci wikiPageWikiLinkText "Aberrant crypt foci".
- Aberrant_crypt_foci wikiPageWikiLinkText "aberrant crypt foci".
- Aberrant_crypt_foci wikiPageUsesTemplate Template:Oncology-stub.
- Aberrant_crypt_foci wikiPageUsesTemplate Template:Reflist.
- Aberrant_crypt_foci subject Category:Digestive_system_neoplasia.
- Aberrant_crypt_foci subject Category:Pathology.
- Aberrant_crypt_foci hypernym Clusters.
- Aberrant_crypt_foci type Organisation.
- Aberrant_crypt_foci type Type.
- Aberrant_crypt_foci type Specialty.
- Aberrant_crypt_foci type Type.
- Aberrant_crypt_foci comment "Aberrant crypt foci (ACF) are clusters of abnormal tube-like glands in the lining of the colon and rectum. Aberrant crypt foci form before colorectal polyps and are one of the earliest changes seen in the colon that may lead to cancer. ACF are, as opposed to normal epithelial cells, apoptosis resistant. When looking for aberrant crypt foci with microscopy, methylene blue is used as a staining agent.".
- Aberrant_crypt_foci label "Aberrant crypt foci".
- Aberrant_crypt_foci sameAs Q4667164.
- Aberrant_crypt_foci sameAs بؤر_الخبيئات_الشاذة.
- Aberrant_crypt_foci sameAs m.057yrr7.
- Aberrant_crypt_foci sameAs Q4667164.
- Aberrant_crypt_foci wasDerivedFrom Aberrant_crypt_foci?oldid=589918522.
- Aberrant_crypt_foci isPrimaryTopicOf Aberrant_crypt_foci.