Matches in DBpedia 2016-04 for { <http://dbpedia.org/resource/AKTIP> ?p ?o }
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- AKTIP abstract "AKT-interacting protein is a protein that in humans is encoded by the AKTIP gene.The mouse homolog of this gene produces fused toes and thymic hyperplasia in heterozygous mutant animals while homozygous mutants die in early development. This gene may play a role in apoptosis as these morphological abnormalities are caused by altered patterns of programmed cell death. The protein encoded by this gene is similar to the ubiquitin ligase domain of other ubiquitin-conjugating enzymes but lacks the conserved cysteine residue that enables those enzymes to conjugate ubiquitin to the target protein. This protein interacts directly with serine/threonine kinase protein kinase B (PKB)/Akt and modulates PKB activity by enhancing the phosphorylation of PKB's regulatory sites. Alternative splicing results in two transcript variants encoding the same protein.".
- AKTIP entrezgene "64400".
- AKTIP wikiPageID "15064708".
- AKTIP wikiPageLength "6954".
- AKTIP wikiPageOutDegree "8".
- AKTIP wikiPageRevisionID "659775022".
- AKTIP wikiPageWikiLink AKT1.
- AKTIP wikiPageWikiLink Bipolar_disorder.
- AKTIP wikiPageWikiLink Gene.
- AKTIP wikiPageWikiLink Protein.
- AKTIP wikiPageWikiLink Protein–protein_interaction.
- AKTIP wikiPageWikiLink Single-nucleotide_polymorphism.
- AKTIP wikiPageWikiLink Suicide.
- AKTIP wikiPageWikiLinkText "AKTIP".
- AKTIP requireManualInspection "no".
- AKTIP summaryText "The mouse homolog of this gene produces fused toes and thymic hyperplasia in heterozygous mutant animals while homozygous mutants die in early development. This gene may play a role in apoptosis as these morphological abnormalities are caused by altered patterns of programmed cell death. The protein encoded by this gene is similar to the ubiquitin ligase domain of other ubiquitin-conjugating enzymes but lacks the conserved cysteine residue that enables those enzymes to conjugate ubiquitin to the target protein. This protein interacts directly with serine/threonine kinase protein kinase B /Akt and modulates PKB activity by enhancing the phosphorylation of PKB's regulatory sites. Alternative splicing results in two transcript variants encoding the same protein.".
- AKTIP updateCitations "yes".
- AKTIP updatePage "yes".
- AKTIP updateProteinBox "yes".
- AKTIP updateSummary "yes".
- AKTIP wikiPageUsesTemplate Template:Cite_journal.
- AKTIP wikiPageUsesTemplate Template:Gene-16-stub.
- AKTIP wikiPageUsesTemplate Template:PBB.
- AKTIP wikiPageUsesTemplate Template:PBB_Controls.
- AKTIP wikiPageUsesTemplate Template:PBB_Further_reading.
- AKTIP wikiPageUsesTemplate Template:PBB_Summary.
- AKTIP wikiPageUsesTemplate Template:Refbegin.
- AKTIP wikiPageUsesTemplate Template:Refend.
- AKTIP wikiPageUsesTemplate Template:Reflist.
- AKTIP hypernym Protein.
- AKTIP type Biomolecule.
- AKTIP type Protein.
- AKTIP type Thing.
- AKTIP type Q206229.
- AKTIP type Q8054.
- AKTIP comment "AKT-interacting protein is a protein that in humans is encoded by the AKTIP gene.The mouse homolog of this gene produces fused toes and thymic hyperplasia in heterozygous mutant animals while homozygous mutants die in early development. This gene may play a role in apoptosis as these morphological abnormalities are caused by altered patterns of programmed cell death.".
- AKTIP label "AKTIP".
- AKTIP sameAs Q18045656.
- AKTIP sameAs m.03hg9hn.
- AKTIP sameAs Q18045656.
- AKTIP wasDerivedFrom AKTIP?oldid=659775022.
- AKTIP isPrimaryTopicOf AKTIP.