Matches in DBpedia 2016-04 for { <http://dbpedia.org/resource/AI-10-49> ?p ?o }
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- AI-10-49 abstract "AI-10-49 is a small molecule inhibitor of leukemic oncoprotein CBFβ-SMHHC developed by the laboratory of John Bushweller (University of Virginia) with efficacy demonstrated by the laboratories of Lucio H. Castilla (University of Massachusetts Medical School) and Monica Guzman (Cornell University). AI-10-49 allosterically binds to CBFβ-SMMHC and disrupts protein-protein interaction between CBFβ-SMMHC and tumor suppressor RUNX1. This inhibitor is under development as an anti-leukemic drug.".
- AI-10-49 casNumber "1256094-72-0".
- AI-10-49 iupacName "2,2'-(5,5'-((Oxybis(ethane-2,1-diyl))bis(oxy))bis(pyridine-5,2-diyl))bis(5-(trifluoromethoxy)-1H-benzo[d]imidazole)".
- AI-10-49 thumbnail AI-10-49.svg?width=300.
- AI-10-49 wikiPageID "46307296".
- AI-10-49 wikiPageLength "8236".
- AI-10-49 wikiPageOutDegree "38".
- AI-10-49 wikiPageRevisionID "703931261".
- AI-10-49 wikiPageWikiLink Adhesion_(medicine).
- AI-10-49 wikiPageWikiLink Allosteric_regulation.
- AI-10-49 wikiPageWikiLink BCL6.
- AI-10-49 wikiPageWikiLink BRD4.
- AI-10-49 wikiPageWikiLink Binding_selectivity.
- AI-10-49 wikiPageWikiLink Carcinogenesis.
- AI-10-49 wikiPageWikiLink Category:Benzimidazoles.
- AI-10-49 wikiPageWikiLink Category:Experimental_cancer_drugs.
- AI-10-49 wikiPageWikiLink Category:Pyridines.
- AI-10-49 wikiPageWikiLink Cell_cycle.
- AI-10-49 wikiPageWikiLink Cellular_differentiation.
- AI-10-49 wikiPageWikiLink Chemotherapy.
- AI-10-49 wikiPageWikiLink Chromosomal_inversion.
- AI-10-49 wikiPageWikiLink Chromosomal_translocation.
- AI-10-49 wikiPageWikiLink Clinical_trial.
- AI-10-49 wikiPageWikiLink Cornell_University.
- AI-10-49 wikiPageWikiLink Cytarabine.
- AI-10-49 wikiPageWikiLink Doxorubicin.
- AI-10-49 wikiPageWikiLink Haematopoiesis.
- AI-10-49 wikiPageWikiLink IC50.
- AI-10-49 wikiPageWikiLink JQ1.
- AI-10-49 wikiPageWikiLink Leukemia.
- AI-10-49 wikiPageWikiLink Lymphatic_system.
- AI-10-49 wikiPageWikiLink Myeloid.
- AI-10-49 wikiPageWikiLink Myeloid_leukemia.
- AI-10-49 wikiPageWikiLink Nutlin.
- AI-10-49 wikiPageWikiLink Oncogene.
- AI-10-49 wikiPageWikiLink P53.
- AI-10-49 wikiPageWikiLink Pharmacokinetics.
- AI-10-49 wikiPageWikiLink Polyethylene_glycol.
- AI-10-49 wikiPageWikiLink Progenitor_cell.
- AI-10-49 wikiPageWikiLink Protein_dimer.
- AI-10-49 wikiPageWikiLink Protein–protein_interaction.
- AI-10-49 wikiPageWikiLink RUNX1.
- AI-10-49 wikiPageWikiLink Transcription_factor.
- AI-10-49 wikiPageWikiLink University_of_Massachusetts_Medical_School.
- AI-10-49 wikiPageWikiLink University_of_Virginia.
- AI-10-49 c "30".
- AI-10-49 casNumber "1256094".
- AI-10-49 f "6".
- AI-10-49 h "22".
- AI-10-49 iupacName "22".
- AI-10-49 molecularWeight "660.52".
- AI-10-49 n "6".
- AI-10-49 o "5".
- AI-10-49 smiles "FCOC1=CC2=CNC=N2".
- AI-10-49 width "250".
- AI-10-49 wikiPageUsesTemplate Template:Drugbox.
- AI-10-49 wikiPageUsesTemplate Template:Orphan.
- AI-10-49 wikiPageUsesTemplate Template:Reflist.
- AI-10-49 subject Category:Benzimidazoles.
- AI-10-49 subject Category:Experimental_cancer_drugs.
- AI-10-49 subject Category:Pyridines.
- AI-10-49 hypernym Inhibitor.
- AI-10-49 type ChemicalSubstance.
- AI-10-49 type Drug.
- AI-10-49 type ChemicalObject.
- AI-10-49 type Thing.
- AI-10-49 type Q8386.
- AI-10-49 comment "AI-10-49 is a small molecule inhibitor of leukemic oncoprotein CBFβ-SMHHC developed by the laboratory of John Bushweller (University of Virginia) with efficacy demonstrated by the laboratories of Lucio H. Castilla (University of Massachusetts Medical School) and Monica Guzman (Cornell University). AI-10-49 allosterically binds to CBFβ-SMMHC and disrupts protein-protein interaction between CBFβ-SMMHC and tumor suppressor RUNX1. This inhibitor is under development as an anti-leukemic drug.".
- AI-10-49 label "AI-10-49".
- AI-10-49 sameAs m.0131vhx9.
- AI-10-49 wasDerivedFrom AI-10-49?oldid=703931261.
- AI-10-49 depiction AI-10-49.svg.
- AI-10-49 isPrimaryTopicOf AI-10-49.