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- ADAM3 abstract "A disintegrin and metalloprotease 3, or ADAM3, belongs to a family of peptidase proteins referred to as ADAMs. Many of these are solely found in spermatogenic cells. This membrane protein is critical for crucial steps in fertilization such as migration of sperm through the uterus to the oviduct as well as binding to the zona pellucida.Numerous studies have detailed that in ADAM3 null mice, the spermatozoa fail to migrate through the utero-tubal junction. Furthermore, knockout of the closely related ADAM1a gene in mice, an estrogen receptor not found in mature spermatozoa, causes loss of surface ADAM3 and decreased zona pellucida binding. Other studies have shown ADAM3-/- mouse spermatozoa fail to show sperm-sperm aggregation, although the significance of this is still unknown. ADAM3 has not yet been found in humans.".
- ADAM3 wikiPageID "44630746".
- ADAM3 wikiPageLength "3493".
- ADAM3 wikiPageOutDegree "17".
- ADAM3 wikiPageRevisionID "701723581".
- ADAM3 wikiPageWikiLink Category:EC_3.4.24.
- ADAM3 wikiPageWikiLink Category:Peptidase.
- ADAM3 wikiPageWikiLink Category:Semen.
- ADAM3 wikiPageWikiLink Cell_(biology).
- ADAM3 wikiPageWikiLink Disintegrin.
- ADAM3 wikiPageWikiLink Estrogen.
- ADAM3 wikiPageWikiLink Fertilisation.
- ADAM3 wikiPageWikiLink Metalloproteinase.
- ADAM3 wikiPageWikiLink Oviduct.
- ADAM3 wikiPageWikiLink Protease.
- ADAM3 wikiPageWikiLink Protein.
- ADAM3 wikiPageWikiLink Sperm.
- ADAM3 wikiPageWikiLink Spermatogenesis.
- ADAM3 wikiPageWikiLink Spermatozoon.
- ADAM3 wikiPageWikiLink Uterotubal_junction.
- ADAM3 wikiPageWikiLink Uterus.
- ADAM3 wikiPageWikiLink Zona_pellucida.
- ADAM3 wikiPageWikiLinkText "ADAM3".
- ADAM3 wikiPageUsesTemplate Template:Enzyme-stub.
- ADAM3 wikiPageUsesTemplate Template:Enzymes.
- ADAM3 wikiPageUsesTemplate Template:Metalloendopeptidases.
- ADAM3 wikiPageUsesTemplate Template:Portal_bar.
- ADAM3 wikiPageUsesTemplate Template:Reflist.
- ADAM3 subject Category:EC_3.4.24.
- ADAM3 subject Category:Peptidase.
- ADAM3 subject Category:Semen.
- ADAM3 comment "A disintegrin and metalloprotease 3, or ADAM3, belongs to a family of peptidase proteins referred to as ADAMs. Many of these are solely found in spermatogenic cells. This membrane protein is critical for crucial steps in fertilization such as migration of sperm through the uterus to the oviduct as well as binding to the zona pellucida.Numerous studies have detailed that in ADAM3 null mice, the spermatozoa fail to migrate through the utero-tubal junction.".
- ADAM3 label "ADAM3".
- ADAM3 sameAs Q17912206.
- ADAM3 sameAs m.012g4ch4.
- ADAM3 sameAs Q17912206.
- ADAM3 wasDerivedFrom ADAM3?oldid=701723581.
- ADAM3 isPrimaryTopicOf ADAM3.