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- ABT-418 abstract "ABT-418 is a drug developed by Abbott, that has nootropic, neuroprotective and anxiolytic effects, and has been researched for treatment of both Alzheimer's disease and ADHD. It acts as an agonist at neural nicotinic acetylcholine receptors, subtype-selective binding with high affinity to the α4β2, α7/5-HT3, and α2β2 nicotinic acetylcholine receptors but not the α3β4 subtype familiar to nicotine. ABT-418 was reasonably effective for both applications and fairly well tolerated, but produced some side effects, principally nausea, and it is unclear whether ABT-418 itself will proceed to clinical development or if another similar drug will be used instead.".
- ABT-418 casNumber "147402-53-7".
- ABT-418 iupacName "3-methyl-5-[(2S)-1-methylpyrrolidin-2-yl]-1,2-oxazole".
- ABT-418 pubchem "119380".
- ABT-418 thumbnail ABT-418.png?width=300.
- ABT-418 wikiPageID "17714359".
- ABT-418 wikiPageLength "7144".
- ABT-418 wikiPageOutDegree "24".
- ABT-418 wikiPageRevisionID "647246279".
- ABT-418 wikiPageWikiLink 5-HT3_receptor.
- ABT-418 wikiPageWikiLink Abbott_Laboratories.
- ABT-418 wikiPageWikiLink Agonist.
- ABT-418 wikiPageWikiLink Alpha-4_beta-2_nicotinic_receptor.
- ABT-418 wikiPageWikiLink Alpha-7_nicotinic_receptor.
- ABT-418 wikiPageWikiLink Alzheimers_disease.
- ABT-418 wikiPageWikiLink Anxiolytic.
- ABT-418 wikiPageWikiLink Attention_deficit_hyperactivity_disorder.
- ABT-418 wikiPageWikiLink Category:Isoxazoles.
- ABT-418 wikiPageWikiLink Category:Nicotinic_agonists.
- ABT-418 wikiPageWikiLink Category:Nootropics.
- ABT-418 wikiPageWikiLink Category:Pyrrolidines.
- ABT-418 wikiPageWikiLink Category:Stimulants.
- ABT-418 wikiPageWikiLink Dissociation_constant.
- ABT-418 wikiPageWikiLink Epiboxidine.
- ABT-418 wikiPageWikiLink Ganglion_type_nicotinic_receptor.
- ABT-418 wikiPageWikiLink Nausea.
- ABT-418 wikiPageWikiLink Neuroprotection.
- ABT-418 wikiPageWikiLink Nicotine.
- ABT-418 wikiPageWikiLink Nicotinic_acetylcholine_receptor.
- ABT-418 wikiPageWikiLink Nootropic.
- ABT-418 wikiPageWikiLink Α2β2.
- ABT-418 wikiPageWikiLinkText "ABT-418".
- ABT-418 c "9".
- ABT-418 casNumber "147402".
- ABT-418 chembl "274525".
- ABT-418 chemspiderid "106627".
- ABT-418 h "14".
- ABT-418 inchi "1".
- ABT-418 inchikey "ILLGYRJAYAAAEW-QMMMGPOBBM".
- ABT-418 iupacName "3".
- ABT-418 molecularWeight "166.22".
- ABT-418 n "2".
- ABT-418 o "1".
- ABT-418 pubchem "119380".
- ABT-418 smiles "CC1=NOC[C@@H]2CCCN2C".
- ABT-418 stdinchi "1".
- ABT-418 stdinchikey "ILLGYRJAYAAAEW-QMMMGPOBSA-N".
- ABT-418 verifiedfields "changed".
- ABT-418 verifiedrevid "477235109".
- ABT-418 width "240".
- ABT-418 wikiPageUsesTemplate Template:Antidementia.
- ABT-418 wikiPageUsesTemplate Template:Anxiolytics.
- ABT-418 wikiPageUsesTemplate Template:Cascite.
- ABT-418 wikiPageUsesTemplate Template:Chemspidercite.
- ABT-418 wikiPageUsesTemplate Template:Cholinergics.
- ABT-418 wikiPageUsesTemplate Template:Drugbox.
- ABT-418 wikiPageUsesTemplate Template:Ebicite.
- ABT-418 wikiPageUsesTemplate Template:Nervous-system-drug-stub.
- ABT-418 wikiPageUsesTemplate Template:Nootropics.
- ABT-418 wikiPageUsesTemplate Template:Reflist.
- ABT-418 wikiPageUsesTemplate Template:Stdinchicite.
- ABT-418 wikiPageUsesTemplate Template:Stimulants.
- ABT-418 subject Category:Isoxazoles.
- ABT-418 subject Category:Nicotinic_agonists.
- ABT-418 subject Category:Nootropics.
- ABT-418 subject Category:Pyrrolidines.
- ABT-418 subject Category:Stimulants.
- ABT-418 hypernym Drug.
- ABT-418 type ChemicalSubstance.
- ABT-418 type Drug.
- ABT-418 type Agonist.
- ABT-418 type Azole.
- ABT-418 type Drug.
- ABT-418 type Heterocycle.
- ABT-418 type Nootropic.
- ABT-418 type Parasympathomimetic.
- ABT-418 type Psychoanaleptic.
- ABT-418 type Stimulant.
- ABT-418 type ChemicalObject.
- ABT-418 type Thing.
- ABT-418 type Q8386.
- ABT-418 comment "ABT-418 is a drug developed by Abbott, that has nootropic, neuroprotective and anxiolytic effects, and has been researched for treatment of both Alzheimer's disease and ADHD. It acts as an agonist at neural nicotinic acetylcholine receptors, subtype-selective binding with high affinity to the α4β2, α7/5-HT3, and α2β2 nicotinic acetylcholine receptors but not the α3β4 subtype familiar to nicotine.".
- ABT-418 label "ABT-418".
- ABT-418 sameAs Q4650418.
- ABT-418 sameAs m.047d662.
- ABT-418 sameAs ABT-418.
- ABT-418 sameAs ABT-418.
- ABT-418 sameAs Q4650418.
- ABT-418 wasDerivedFrom ABT-418?oldid=647246279.
- ABT-418 depiction ABT-418.png.
- ABT-418 isPrimaryTopicOf ABT-418.