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- AB-001 abstract "AB-001 or 1-pentyl-3-(1-adamantoyl)indole is a designer drug that was found as an ingredient in synthetic cannabis smoking blends in Ireland in 2010 and Hungary and Germany in 2011. It is unclear who AB-001 was originally developed by, but it is structurally related to compounds such as AM-1248 and its corresponding 1-(tetrahydropyran-4-ylmethyl) analogue, which are known to be potent cannabinoid agonists with moderate to high selectivity for CB2 over CB1. The first published synthesis and pharmacological evaluation of AB-001 revealed that it acts as a full agonist at CB1 (EC50 = 35 nM) and CB2 receptors (EC50 = 48 nM). However, AB-001 was found to possess only weak cannabimimetic effects in rats at doses up to 30 mg/kg, making it less potent than the carboxamide analogue APICA, which possesses potent cannabimimetic activity at doses of 3 mg/kg.".
- AB-001 casNumber "1345973-49-0".
- AB-001 fdaUniiCode "H657DIA015".
- AB-001 iupacName "1-pentyl-3-(adamant-1-oyl)indole".
- AB-001 pubchem "57404070".
- AB-001 thumbnail AB-001_structure.png?width=300.
- AB-001 wikiPageID "33362332".
- AB-001 wikiPageLength "5844".
- AB-001 wikiPageOutDegree "20".
- AB-001 wikiPageRevisionID "708358082".
- AB-001 wikiPageWikiLink A-834,735.
- AB-001 wikiPageWikiLink AB-005.
- AB-001 wikiPageWikiLink AM-1248.
- AB-001 wikiPageWikiLink APICA_(synthetic_cannabinoid_drug).
- AB-001 wikiPageWikiLink Cannabinoid_receptor_type_1.
- AB-001 wikiPageWikiLink Cannabinoid_receptor_type_2.
- AB-001 wikiPageWikiLink Category:Adamantanes.
- AB-001 wikiPageWikiLink Category:Adamantanoylindoles.
- AB-001 wikiPageWikiLink Category:Cannabinoids.
- AB-001 wikiPageWikiLink Category:Designer_drugs.
- AB-001 wikiPageWikiLink Designer_drug.
- AB-001 wikiPageWikiLink JWH-018.
- AB-001 wikiPageWikiLink JWH-250.
- AB-001 wikiPageWikiLink N-(S)-Fenchyl-1-(2-morpholinoethyl)-7-methoxyindole-3-carboxamide.
- AB-001 wikiPageWikiLink RCS-4.
- AB-001 wikiPageWikiLink RCS-8.
- AB-001 wikiPageWikiLink Synthetic_cannabinoids.
- AB-001 wikiPageWikiLink UR-144.
- AB-001 wikiPageWikiLinkText "1-pentyl-3-(1-adamantoyl)indole".
- AB-001 wikiPageWikiLinkText "AB-001".
- AB-001 wikiPageWikiLinkText "List of miscellaneous designer cannabinoids".
- AB-001 c "24".
- AB-001 casNumber "1345973".
- AB-001 chemspiderid "26286891".
- AB-001 drugbankRef "=".
- AB-001 h "31".
- AB-001 inchi "1".
- AB-001 inchikey "SHWDYCMMUPPWQM-UHFFFAOYAF".
- AB-001 iupacName "1".
- AB-001 legalCa "Schedule II".
- AB-001 legalDe "Anlage II".
- AB-001 molecularWeight "349.508".
- AB-001 n "1".
- AB-001 o "1".
- AB-001 pubchem "57404070".
- AB-001 smiles "CCCCCn1ccCC34CC5CCCCC4".
- AB-001 stdinchi "1".
- AB-001 stdinchikey "SHWDYCMMUPPWQM-UHFFFAOYSA-N".
- AB-001 unii "H657DIA015".
- AB-001 verifiedfields "changed".
- AB-001 verifiedrevid "460440720".
- AB-001 watchedfields "changed".
- AB-001 width "200".
- AB-001 wikiPageUsesTemplate Template:Cannabinoid-stub.
- AB-001 wikiPageUsesTemplate Template:Cannabinoids.
- AB-001 wikiPageUsesTemplate Template:Cascite.
- AB-001 wikiPageUsesTemplate Template:Chemspidercite.
- AB-001 wikiPageUsesTemplate Template:Drugbankcite.
- AB-001 wikiPageUsesTemplate Template:Drugbox.
- AB-001 wikiPageUsesTemplate Template:Fdacite.
- AB-001 wikiPageUsesTemplate Template:Reflist.
- AB-001 wikiPageUsesTemplate Template:Stdinchicite.
- AB-001 subject Category:Adamantanes.
- AB-001 subject Category:Adamantanoylindoles.
- AB-001 subject Category:Cannabinoids.
- AB-001 subject Category:Designer_drugs.
- AB-001 hypernym Drug.
- AB-001 type ChemicalSubstance.
- AB-001 type Drug.
- AB-001 type Cannabinoid.
- AB-001 type Chemical.
- AB-001 type Drug.
- AB-001 type Hydrocarbon.
- AB-001 type ChemicalObject.
- AB-001 type Thing.
- AB-001 type Q8386.
- AB-001 comment "AB-001 or 1-pentyl-3-(1-adamantoyl)indole is a designer drug that was found as an ingredient in synthetic cannabis smoking blends in Ireland in 2010 and Hungary and Germany in 2011. It is unclear who AB-001 was originally developed by, but it is structurally related to compounds such as AM-1248 and its corresponding 1-(tetrahydropyran-4-ylmethyl) analogue, which are known to be potent cannabinoid agonists with moderate to high selectivity for CB2 over CB1.".
- AB-001 label "AB-001".
- AB-001 sameAs Q4649999.
- AB-001 sameAs m.0h7lgzx.
- AB-001 sameAs AB-001.
- AB-001 sameAs AB-001.
- AB-001 sameAs Q4649999.
- AB-001 wasDerivedFrom AB-001?oldid=708358082.
- AB-001 depiction AB-001_structure.png.
- AB-001 isPrimaryTopicOf AB-001.