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- A-412,997 abstract "A-412,997 is a drug which acts as a dopamine agonist that is used in scientific research. It is the first drug developed that is a highly selective agonist for the D4 subtype, with significantly improved selectivity over older D4-preferring compounds such as PD-168,077 and CP-226,269. In animal tests it improved cognitive performance in rats to a similar extent as methylphenidate, but without producing place preference or other signs of abuse liability. Also unlike other dopamine agonists, selective D4 agonists do not cause side effects such as sedation and nausea, and so might have advantages over older dopamine agonist drugs.".
- A-412,997 casNumber "630116-49-3".
- A-412,997 casSupplemental "1347744-96-0 (di‑hydrochloride)".
- A-412,997 iupacName "N-(3-methylphenyl)-2-(4-pyridin-2-ylpiperidin-1-yl)acetamide".
- A-412,997 pubchem "10425450".
- A-412,997 thumbnail A-412,997.png?width=300.
- A-412,997 wikiPageID "17504769".
- A-412,997 wikiPageLength "4467".
- A-412,997 wikiPageOutDegree "12".
- A-412,997 wikiPageRevisionID "691539477".
- A-412,997 wikiPageWikiLink CP-226,269.
- A-412,997 wikiPageWikiLink Category:Acetanilides.
- A-412,997 wikiPageWikiLink Category:Dopamine_agonists.
- A-412,997 wikiPageWikiLink Category:Piperidines.
- A-412,997 wikiPageWikiLink Category:Pyridines.
- A-412,997 wikiPageWikiLink Dopamine_agonist.
- A-412,997 wikiPageWikiLink Dopamine_receptor_D4.
- A-412,997 wikiPageWikiLink Hydrochloride.
- A-412,997 wikiPageWikiLink Methylphenidate.
- A-412,997 wikiPageWikiLink Nausea.
- A-412,997 wikiPageWikiLink PD-168,077.
- A-412,997 wikiPageWikiLink Sedation.
- A-412,997 wikiPageWikiLinkText "A-412,997".
- A-412,997 c "19".
- A-412,997 casNumber "630116".
- A-412,997 casSupplemental "1347744".
- A-412,997 chembl "375596".
- A-412,997 chemspiderid "8600878".
- A-412,997 h "23".
- A-412,997 inchi "1".
- A-412,997 inchikey "JFCDMGGMCUKHST-UHFFFAOYAU".
- A-412,997 iupacName "N--2-acetamide".
- A-412,997 iupharLigand "3301".
- A-412,997 molecularWeight "309.405".
- A-412,997 n "3".
- A-412,997 o "1".
- A-412,997 pubchem "10425450".
- A-412,997 smiles "CC1=CC=CC=C1".
- A-412,997 stdinchi "1".
- A-412,997 stdinchikey "JFCDMGGMCUKHST-UHFFFAOYSA-N".
- A-412,997 verifiedrevid "477234844".
- A-412,997 wikiPageUsesTemplate Template:Chemspidercite.
- A-412,997 wikiPageUsesTemplate Template:Dopaminergics.
- A-412,997 wikiPageUsesTemplate Template:Drugbox.
- A-412,997 wikiPageUsesTemplate Template:Ebicite.
- A-412,997 wikiPageUsesTemplate Template:Nervous-system-drug-stub.
- A-412,997 wikiPageUsesTemplate Template:Reflist.
- A-412,997 wikiPageUsesTemplate Template:Stdinchicite.
- A-412,997 subject Category:Acetanilides.
- A-412,997 subject Category:Dopamine_agonists.
- A-412,997 subject Category:Piperidines.
- A-412,997 subject Category:Pyridines.
- A-412,997 hypernym Drug.
- A-412,997 type Agent.
- A-412,997 type ChemicalSubstance.
- A-412,997 type Drug.
- A-412,997 type Agent.
- A-412,997 type Agonist.
- A-412,997 type Chemical.
- A-412,997 type Drug.
- A-412,997 type Heterocycle.
- A-412,997 type ChemicalObject.
- A-412,997 type Thing.
- A-412,997 type Q8386.
- A-412,997 comment "A-412,997 is a drug which acts as a dopamine agonist that is used in scientific research. It is the first drug developed that is a highly selective agonist for the D4 subtype, with significantly improved selectivity over older D4-preferring compounds such as PD-168,077 and CP-226,269. In animal tests it improved cognitive performance in rats to a similar extent as methylphenidate, but without producing place preference or other signs of abuse liability.".
- A-412,997 label "A-412,997".
- A-412,997 sameAs Q4646874.
- A-412,997 sameAs m.04cy776.
- A-412,997 sameAs A-412,997.
- A-412,997 sameAs A-412,997.
- A-412,997 sameAs Q4646874.
- A-412,997 wasDerivedFrom A-412,997?oldid=691539477.
- A-412,997 depiction A-412,997.png.
- A-412,997 isPrimaryTopicOf A-412,997.