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- A-372159 abstract "A-372159 is a drug which acts as a potent and selective partial agonist for the 5HT2C receptor, with more than 100x selectivity over the closely related 5-HT2B receptor and a Ki of 3nM. It has been found to produce anorectic effects in animal studies and produced significant weight loss in rats with no development of tolerance or serious side effects.".
- A-372159 casNumber "313543-60-1".
- A-372159 iupacName "(8aS,12aR)-2-(4-isopropoxy-2-(trifluoromethyl)phenyl)-6,7,8a,9,10,11,12,12a-octahydro-5H-[1,4]oxazepino[2,3,4-hi]pyrido[4,3-b]indole".
- A-372159 thumbnail A-372,159_structure.png?width=300.
- A-372159 wikiPageID "20289211".
- A-372159 wikiPageLength "2201".
- A-372159 wikiPageOutDegree "11".
- A-372159 wikiPageRevisionID "691538782".
- A-372159 wikiPageWikiLink 5-HT2B_receptor.
- A-372159 wikiPageWikiLink 5-HT2C_receptor.
- A-372159 wikiPageWikiLink Anorectic.
- A-372159 wikiPageWikiLink Category:Nitrogen_heterocycles.
- A-372159 wikiPageWikiLink Category:Organofluorides.
- A-372159 wikiPageWikiLink Category:Oxygen_heterocycles.
- A-372159 wikiPageWikiLink Category:Phenol_ethers.
- A-372159 wikiPageWikiLink Category:Serotonin_receptor_agonists.
- A-372159 wikiPageWikiLink Dissociation_constant.
- A-372159 wikiPageWikiLink Partial_agonist.
- A-372159 wikiPageWikiLink Receptor_(biochemistry).
- A-372159 wikiPageWikiLinkText "A-372159".
- A-372159 c "24".
- A-372159 casNumber "313543".
- A-372159 chemspiderid "9605283".
- A-372159 f "3".
- A-372159 h "27".
- A-372159 inchi "1".
- A-372159 inchikey "LADKOBQJOCFCQU-FPOVZHCZBZ".
- A-372159 iupacName "-2".
- A-372159 molecularWeight "432.478".
- A-372159 n "2".
- A-372159 o "2".
- A-372159 smiles "FCF".
- A-372159 stdinchi "1".
- A-372159 stdinchikey "LADKOBQJOCFCQU-FPOVZHCZSA-N".
- A-372159 verifiedrevid "399345932".
- A-372159 width "220".
- A-372159 wikiPageUsesTemplate Template:Chemspidercite.
- A-372159 wikiPageUsesTemplate Template:Drugbox.
- A-372159 wikiPageUsesTemplate Template:Nervous-system-drug-stub.
- A-372159 wikiPageUsesTemplate Template:Reflist.
- A-372159 wikiPageUsesTemplate Template:Serotonergics.
- A-372159 wikiPageUsesTemplate Template:Stdinchicite.
- A-372159 subject Category:Nitrogen_heterocycles.
- A-372159 subject Category:Organofluorides.
- A-372159 subject Category:Oxygen_heterocycles.
- A-372159 subject Category:Phenol_ethers.
- A-372159 subject Category:Serotonin_receptor_agonists.
- A-372159 hypernym Drug.
- A-372159 type ChemicalSubstance.
- A-372159 type Drug.
- A-372159 type Agonist.
- A-372159 type Chemical.
- A-372159 type Drug.
- A-372159 type Ether.
- A-372159 type Heterocycle.
- A-372159 type Organofluoride.
- A-372159 type Organohalide.
- A-372159 type Organofluoride.
- A-372159 type Organohalide.
- A-372159 type ChemicalObject.
- A-372159 type Thing.
- A-372159 type Q8386.
- A-372159 comment "A-372159 is a drug which acts as a potent and selective partial agonist for the 5HT2C receptor, with more than 100x selectivity over the closely related 5-HT2B receptor and a Ki of 3nM. It has been found to produce anorectic effects in animal studies and produced significant weight loss in rats with no development of tolerance or serious side effects.".
- A-372159 label "A-372159".
- A-372159 sameAs Q4646870.
- A-372159 sameAs m.04zzk9w.
- A-372159 sameAs A-372,159.
- A-372159 sameAs A-372,159.
- A-372159 sameAs Q4646870.
- A-372159 wasDerivedFrom A-372159?oldid=691538782.
- A-372159 depiction A-372,159_structure.png.
- A-372159 isPrimaryTopicOf A-372159.