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- 6-Deoxyerythronolide_B_synthase abstract "6-Deoxyerythronolide B Synthase or DEBS has been identified as a Type 1 polyketide synthase. DEBS is found in Saccharopolyspora erythraea and responsible for the synthesis of the macrolide ring which is the precursor of the antibiotic erythromycin. There have been three categories of polyketide synthases identified to date, type 1, 2 and 3. Type one synthases involve large multidomain proteins containing all the sites necessary for polyketide synthesis. Type two synthases contain active sites distributed among several smaller polypeptides, and type three synthases are large multi-protein complexes containing modules which have a single active site for each and every step of polyketide synthesis. In the case of DEBS, there are three large multi-functional proteins, DEBS 1,2, and 3, that each exist as a dimer of two modules. Each module consists of a minimum of a Ketosynthase (KS), Acyl carrier protein (ACP) site, and acyltransferase (AT), but may also contain a Ketoreductase (KR), Dehydrotase (DH), and Enol Reductase (ER) for additional reduction reactions. The DEBS complex also contains a Loading Domain on module 1 consisting of an acyl carrier protein and an acyltransferase. The terminal Thioesterase acts solely to terminate DEBS polyketide synthesis and cyclize the macrolide ring.".
- 6-Deoxyerythronolide_B_synthase wikiPageID "31640520".
- 6-Deoxyerythronolide_B_synthase wikiPageLength "18756".
- 6-Deoxyerythronolide_B_synthase wikiPageOutDegree "69".
- 6-Deoxyerythronolide_B_synthase wikiPageRevisionID "704006496".
- 6-Deoxyerythronolide_B_synthase wikiPageWikiLink Acetic_acid.
- 6-Deoxyerythronolide_B_synthase wikiPageWikiLink Acetyl-CoA.
- 6-Deoxyerythronolide_B_synthase wikiPageWikiLink Acyl_carrier_protein.
- 6-Deoxyerythronolide_B_synthase wikiPageWikiLink Acyltransferase.
- 6-Deoxyerythronolide_B_synthase wikiPageWikiLink Alcohol.
- 6-Deoxyerythronolide_B_synthase wikiPageWikiLink Allosteric_regulation.
- 6-Deoxyerythronolide_B_synthase wikiPageWikiLink Amino_acid.
- 6-Deoxyerythronolide_B_synthase wikiPageWikiLink Antibiotics.
- 6-Deoxyerythronolide_B_synthase wikiPageWikiLink Antimicrobial.
- 6-Deoxyerythronolide_B_synthase wikiPageWikiLink Bacteria.
- 6-Deoxyerythronolide_B_synthase wikiPageWikiLink Biosynthesis.
- 6-Deoxyerythronolide_B_synthase wikiPageWikiLink Carbon.
- 6-Deoxyerythronolide_B_synthase wikiPageWikiLink Carbonyl.
- 6-Deoxyerythronolide_B_synthase wikiPageWikiLink Carbon–carbon_bond.
- 6-Deoxyerythronolide_B_synthase wikiPageWikiLink Category:EC_6.4.
- 6-Deoxyerythronolide_B_synthase wikiPageWikiLink Chain_transfer.
- 6-Deoxyerythronolide_B_synthase wikiPageWikiLink Cytoplasm.
- 6-Deoxyerythronolide_B_synthase wikiPageWikiLink Dehydratase.
- 6-Deoxyerythronolide_B_synthase wikiPageWikiLink Dehydration.
- 6-Deoxyerythronolide_B_synthase wikiPageWikiLink Dimer_(chemistry).
- 6-Deoxyerythronolide_B_synthase wikiPageWikiLink Double_bond.
- 6-Deoxyerythronolide_B_synthase wikiPageWikiLink Enzyme.
- 6-Deoxyerythronolide_B_synthase wikiPageWikiLink Erythromycin.
- 6-Deoxyerythronolide_B_synthase wikiPageWikiLink Fatty_acid.
- 6-Deoxyerythronolide_B_synthase wikiPageWikiLink Fatty_acid_synthesis.
- 6-Deoxyerythronolide_B_synthase wikiPageWikiLink Gene.
- 6-Deoxyerythronolide_B_synthase wikiPageWikiLink Genetic_engineering.
- 6-Deoxyerythronolide_B_synthase wikiPageWikiLink Glycosyltransferase.
- 6-Deoxyerythronolide_B_synthase wikiPageWikiLink Hydroxyl.
- 6-Deoxyerythronolide_B_synthase wikiPageWikiLink In_vitro.
- 6-Deoxyerythronolide_B_synthase wikiPageWikiLink In_vivo.
- 6-Deoxyerythronolide_B_synthase wikiPageWikiLink Keto-synthase.
- 6-Deoxyerythronolide_B_synthase wikiPageWikiLink Macrolide.
- 6-Deoxyerythronolide_B_synthase wikiPageWikiLink Malonic_acid.
- 6-Deoxyerythronolide_B_synthase wikiPageWikiLink Mammal.
- 6-Deoxyerythronolide_B_synthase wikiPageWikiLink Methylmalonyl-CoA.
- 6-Deoxyerythronolide_B_synthase wikiPageWikiLink Molecule.
- 6-Deoxyerythronolide_B_synthase wikiPageWikiLink Multiprotein_complex.
- 6-Deoxyerythronolide_B_synthase wikiPageWikiLink Mycobacterium_smegmatis.
- 6-Deoxyerythronolide_B_synthase wikiPageWikiLink Nicotinamide_adenine_dinucleotide_phosphate.
- 6-Deoxyerythronolide_B_synthase wikiPageWikiLink Organic_compound.
- 6-Deoxyerythronolide_B_synthase wikiPageWikiLink Oxidoreductase.
- 6-Deoxyerythronolide_B_synthase wikiPageWikiLink Peptide.
- 6-Deoxyerythronolide_B_synthase wikiPageWikiLink Pharmaceutical_industry.
- 6-Deoxyerythronolide_B_synthase wikiPageWikiLink Phosphopantetheine.
- 6-Deoxyerythronolide_B_synthase wikiPageWikiLink Polyketide.
- 6-Deoxyerythronolide_B_synthase wikiPageWikiLink Polyketide_synthase.
- 6-Deoxyerythronolide_B_synthase wikiPageWikiLink Prokaryote.
- 6-Deoxyerythronolide_B_synthase wikiPageWikiLink Propionyl-CoA.
- 6-Deoxyerythronolide_B_synthase wikiPageWikiLink Reagent.
- 6-Deoxyerythronolide_B_synthase wikiPageWikiLink Redox.
- 6-Deoxyerythronolide_B_synthase wikiPageWikiLink Saturated_fat.
- 6-Deoxyerythronolide_B_synthase wikiPageWikiLink Serine.
- 6-Deoxyerythronolide_B_synthase wikiPageWikiLink Sirolimus.
- 6-Deoxyerythronolide_B_synthase wikiPageWikiLink Stereocenter.
- 6-Deoxyerythronolide_B_synthase wikiPageWikiLink Stereochemistry.
- 6-Deoxyerythronolide_B_synthase wikiPageWikiLink Stereoisomerism.
- 6-Deoxyerythronolide_B_synthase wikiPageWikiLink Stereospecificity.
- 6-Deoxyerythronolide_B_synthase wikiPageWikiLink Synthase.
- 6-Deoxyerythronolide_B_synthase wikiPageWikiLink Thioester.
- 6-Deoxyerythronolide_B_synthase wikiPageWikiLink Thioesterase.
- 6-Deoxyerythronolide_B_synthase wikiPageWikiLink Unsaturated_fat.
- 6-Deoxyerythronolide_B_synthase wikiPageWikiLink Upstream_and_downstream_(transduction).
- 6-Deoxyerythronolide_B_synthase wikiPageWikiLink Yeast.
- 6-Deoxyerythronolide_B_synthase wikiPageWikiLinkText "6-Deoxyerythronolide B synthase".
- 6-Deoxyerythronolide_B_synthase wikiPageUsesTemplate Template:Carbon-carbon_ligases.
- 6-Deoxyerythronolide_B_synthase wikiPageUsesTemplate Template:Enzymes.
- 6-Deoxyerythronolide_B_synthase wikiPageUsesTemplate Template:Portal_bar.
- 6-Deoxyerythronolide_B_synthase wikiPageUsesTemplate Template:Reflist.
- 6-Deoxyerythronolide_B_synthase subject Category:EC_6.4.
- 6-Deoxyerythronolide_B_synthase comment "6-Deoxyerythronolide B Synthase or DEBS has been identified as a Type 1 polyketide synthase. DEBS is found in Saccharopolyspora erythraea and responsible for the synthesis of the macrolide ring which is the precursor of the antibiotic erythromycin. There have been three categories of polyketide synthases identified to date, type 1, 2 and 3. Type one synthases involve large multidomain proteins containing all the sites necessary for polyketide synthesis.".
- 6-Deoxyerythronolide_B_synthase label "6-Deoxyerythronolide B synthase".
- 6-Deoxyerythronolide_B_synthase sameAs Q4641535.
- 6-Deoxyerythronolide_B_synthase sameAs m.0gmbyjj.
- 6-Deoxyerythronolide_B_synthase sameAs Q4641535.
- 6-Deoxyerythronolide_B_synthase wasDerivedFrom 6-Deoxyerythronolide_B_synthase?oldid=704006496.
- 6-Deoxyerythronolide_B_synthase isPrimaryTopicOf 6-Deoxyerythronolide_B_synthase.