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- 4-Androstene-3,6,17-trione abstract "4-Androstene-3,6,17-trione (4-AT; also marketed as 6-OXO or 4-etioallocholen-3,6,17-trione) is a drug or nutritional supplement that may increase the testosterone-estrogen ratio, but has no proven effect on body composition. Its use can be detected in urine.4-AT is a potent irreversible aromatase inhibitor that inhibits estrogen biosynthesis by permanently binding and inactivating aromatase in adipose and peripheral tissue. Aromatase is responsible for the conversion of testosterone to estradiol. Blocking aromatase causes the body to decrease in levels of estradiol, which then results in increase of LH and consequently, testosterone. Since testosterone has myotropic activity and estradiol does not, elevated testosterone levels increase muscle mass. However, there appear to be no human or animal studies testing the hypothesis that 4-AT will produce an anabolic effect.4-AT is also used by steroid or prohormone users to counteract estrogen level increases caused by aromatization during their steroid cycle. This helps minimize side effects such as gynecomastia but can lead to acne. Also, after a steroid cycle, the compound may be used to shorten the recovery from the testicular suppression that can be the result of the use of steroids.Baylor University conducted an eight-week study to determine the effects of 300 mg or 600 mg of 4-AT in resistance-trained males. Compared to baseline, free testosterone increased by 90% for 300 mg group and 84% for 600 mg group, respectively. Also dihydrotestosterone and the ratio of free testosterone to estradiol increased significantly. The report concluded that \"[t]he results of this study indicate that eight weeks of 6-OXO supplementation had no effect on body composition or clinical safety markers, but incompletely inhibited aromatase activity and significantly increased endogenous DHT levels that were attenuated after a three-week washout period\". This study did not utilize a control group and was funded in part by two producers of commercial 4-AT.In a FDA Warning Letter dated July 7, 2006, the U.S. Food and Drug Administration (FDA) argues that marketing of 4-AT violates the Federal Food, Drug, and Cosmetic Act and as such products containing it are adulterated by legal definition.In 2008, Health Canada issued a warning that 4-AT had a health risk related to blood clotting and recommended all users immediately cease use.".
- 4-Androstene-3,6,17-trione casNumber "2243-06-3".
- 4-Androstene-3,6,17-trione iupacName "(10R,13S)-10,13-dimethyl-".
- 4-Androstene-3,6,17-trione iupacName "1,7,8,9,10,11,12,13,15,16-".
- 4-Androstene-3,6,17-trione iupacName "3,6,17(14H)-trione".
- 4-Androstene-3,6,17-trione iupacName "decahydro-2H-cyclopenta[alpha]phenanthrene-".
- 4-Androstene-3,6,17-trione thumbnail 4-Androstene-3,6,17-trione.png?width=300.
- 4-Androstene-3,6,17-trione wikiPageID "5048486".
- 4-Androstene-3,6,17-trione wikiPageLength "7387".
- 4-Androstene-3,6,17-trione wikiPageOutDegree "25".
- 4-Androstene-3,6,17-trione wikiPageRevisionID "653429128".
- 4-Androstene-3,6,17-trione wikiPageWikiLink Acne_vulgaris.
- 4-Androstene-3,6,17-trione wikiPageWikiLink Adipose_tissue.
- 4-Androstene-3,6,17-trione wikiPageWikiLink Anabolic_steroid.
- 4-Androstene-3,6,17-trione wikiPageWikiLink Aromatase.
- 4-Androstene-3,6,17-trione wikiPageWikiLink Aromatase_inhibitor.
- 4-Androstene-3,6,17-trione wikiPageWikiLink Category:Anabolic_steroids.
- 4-Androstene-3,6,17-trione wikiPageWikiLink Category:Bodybuilding_supplements.
- 4-Androstene-3,6,17-trione wikiPageWikiLink Category:Exercise_physiology.
- 4-Androstene-3,6,17-trione wikiPageWikiLink Dietary_supplement.
- 4-Androstene-3,6,17-trione wikiPageWikiLink Dihydrotestosterone.
- 4-Androstene-3,6,17-trione wikiPageWikiLink Drug.
- 4-Androstene-3,6,17-trione wikiPageWikiLink Ergogenic_use_of_anabolic_steroids.
- 4-Androstene-3,6,17-trione wikiPageWikiLink Estradiol.
- 4-Androstene-3,6,17-trione wikiPageWikiLink Estrogen.
- 4-Androstene-3,6,17-trione wikiPageWikiLink FDA_Warning_Letter.
- 4-Androstene-3,6,17-trione wikiPageWikiLink Food_and_Drug_Administration.
- 4-Androstene-3,6,17-trione wikiPageWikiLink Gynecomastia.
- 4-Androstene-3,6,17-trione wikiPageWikiLink Health_Canada.
- 4-Androstene-3,6,17-trione wikiPageWikiLink Luteinizing_hormone.
- 4-Androstene-3,6,17-trione wikiPageWikiLink Prohormone.
- 4-Androstene-3,6,17-trione wikiPageWikiLink Testosterone.
- 4-Androstene-3,6,17-trione wikiPageWikiLink World_Anti-Doping_Agency.
- 4-Androstene-3,6,17-trione wikiPageWikiLinkText "4-Androstene-3,6,17-trione".
- 4-Androstene-3,6,17-trione wikiPageWikiLinkText "6-OXO Extreme".
- 4-Androstene-3,6,17-trione c "19".
- 4-Androstene-3,6,17-trione casNumber "2243-06-03".
- 4-Androstene-3,6,17-trione chemspiderid "133080".
- 4-Androstene-3,6,17-trione h "24".
- 4-Androstene-3,6,17-trione inchi "1".
- 4-Androstene-3,6,17-trione inchikey "PJMNEPMSGCRSRC-IEVKOWOJBO".
- 4-Androstene-3,6,17-trione iupacName "-1013".
- 4-Androstene-3,6,17-trione iupacName "1789101112131516".
- 4-Androstene-3,6,17-trione iupacName "3617".
- 4-Androstene-3,6,17-trione iupacName "decahydro-2H-cyclopenta[alpha]phenanthrene-".
- 4-Androstene-3,6,17-trione legalStatus "Banned by World Anti-Doping Agency".
- 4-Androstene-3,6,17-trione molecularWeight "300.39".
- 4-Androstene-3,6,17-trione o "3".
- 4-Androstene-3,6,17-trione routesOfAdministration "oral".
- 4-Androstene-3,6,17-trione smiles "O=C4\C1=C\CCC[C@@]1C".
- 4-Androstene-3,6,17-trione stdinchi "1".
- 4-Androstene-3,6,17-trione stdinchikey "PJMNEPMSGCRSRC-IEVKOWOJSA-N".
- 4-Androstene-3,6,17-trione verifiedrevid "447560771".
- 4-Androstene-3,6,17-trione wikiPageUsesTemplate Template:Androgenics.
- 4-Androstene-3,6,17-trione wikiPageUsesTemplate Template:Cascite.
- 4-Androstene-3,6,17-trione wikiPageUsesTemplate Template:Chemspidercite.
- 4-Androstene-3,6,17-trione wikiPageUsesTemplate Template:Citation_needed.
- 4-Androstene-3,6,17-trione wikiPageUsesTemplate Template:Drugbankcite.
- 4-Androstene-3,6,17-trione wikiPageUsesTemplate Template:Drugbox.
- 4-Androstene-3,6,17-trione wikiPageUsesTemplate Template:Estrogenics.
- 4-Androstene-3,6,17-trione wikiPageUsesTemplate Template:Stdinchicite.
- 4-Androstene-3,6,17-trione subject Category:Anabolic_steroids.
- 4-Androstene-3,6,17-trione subject Category:Bodybuilding_supplements.
- 4-Androstene-3,6,17-trione subject Category:Exercise_physiology.
- 4-Androstene-3,6,17-trione hypernym Drug.
- 4-Androstene-3,6,17-trione type ChemicalSubstance.
- 4-Androstene-3,6,17-trione type Drug.
- 4-Androstene-3,6,17-trione type Androgen.
- 4-Androstene-3,6,17-trione type Redirect.
- 4-Androstene-3,6,17-trione type Steroid.
- 4-Androstene-3,6,17-trione type ChemicalObject.
- 4-Androstene-3,6,17-trione type Thing.
- 4-Androstene-3,6,17-trione type Q8386.
- 4-Androstene-3,6,17-trione comment "4-Androstene-3,6,17-trione (4-AT; also marketed as 6-OXO or 4-etioallocholen-3,6,17-trione) is a drug or nutritional supplement that may increase the testosterone-estrogen ratio, but has no proven effect on body composition. Its use can be detected in urine.4-AT is a potent irreversible aromatase inhibitor that inhibits estrogen biosynthesis by permanently binding and inactivating aromatase in adipose and peripheral tissue.".
- 4-Androstene-3,6,17-trione label "4-Androstene-3,6,17-trione".
- 4-Androstene-3,6,17-trione sameAs Q4637100.
- 4-Androstene-3,6,17-trione sameAs m.0d0g68.
- 4-Androstene-3,6,17-trione sameAs 4-Androsten-3,6,17-trion.
- 4-Androstene-3,6,17-trione sameAs 4-Androsten-3,6,17-trion.
- 4-Androstene-3,6,17-trione sameAs Q4637100.
- 4-Androstene-3,6,17-trione wasDerivedFrom 4-Androstene-3,6,17-trione?oldid=653429128.
- 4-Androstene-3,6,17-trione depiction 4-Androstene-3,6,17-trione.png.
- 4-Androstene-3,6,17-trione isPrimaryTopicOf 4-Androstene-3,6,17-trione.