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- 3-Indolepropionic_acid abstract "3-Indolepropionic acid (IPA), or indole-3-propionic acid, is a potent neuroprotective antioxidant and plant auxin that is being studied for therapeutic use in Alzheimer's disease. It is endogenously produced within the human microbiome and detectable in humans only when the bacteria Clostridium sporogenes is present in the gastrointestinal tract. In individuals who lack C. sporogenes colonization, IPA is not detectable in the blood. In order to synthesize IPA, C. sporogenes metabolizes tryptophan into indole and then subsequently 3-indolepropionic acid.IPA is an even more potent scavenger of hydroxyl radicals than melatonin. Similar to melatonin but unlike other antioxidants, it scavenges radicals without subsequently generating reactive and pro-oxidant intermediate compounds. C. sporogenes is the only bacteria known to synthesize 3-indolepropionic acid in vivo at levels which are subsequently detectable in the blood stream of the host.".
- 3-Indolepropionic_acid thumbnail 3-Indolepropionic_acid_skeletal.svg?width=300.
- 3-Indolepropionic_acid wikiPageID "48181262".
- 3-Indolepropionic_acid wikiPageLength "10392".
- 3-Indolepropionic_acid wikiPageOutDegree "13".
- 3-Indolepropionic_acid wikiPageRevisionID "696459955".
- 3-Indolepropionic_acid wikiPageWikiLink Alzheimers_disease.
- 3-Indolepropionic_acid wikiPageWikiLink Antioxidant.
- 3-Indolepropionic_acid wikiPageWikiLink Auxin.
- 3-Indolepropionic_acid wikiPageWikiLink Category:Antioxidants.
- 3-Indolepropionic_acid wikiPageWikiLink Category:Indoles.
- 3-Indolepropionic_acid wikiPageWikiLink Category:Propionic_acids.
- 3-Indolepropionic_acid wikiPageWikiLink Clostridium_sporogenes.
- 3-Indolepropionic_acid wikiPageWikiLink Human_microbiota.
- 3-Indolepropionic_acid wikiPageWikiLink Hydroxyl_radical.
- 3-Indolepropionic_acid wikiPageWikiLink Indole.
- 3-Indolepropionic_acid wikiPageWikiLink Melatonin.
- 3-Indolepropionic_acid wikiPageWikiLink Neuroprotection.
- 3-Indolepropionic_acid wikiPageWikiLink Tryptophan.
- 3-Indolepropionic_acid wikiPageWikiLinkText "3-Indolepropionic acid".
- 3-Indolepropionic_acid atcPrefix "none".
- 3-Indolepropionic_acid c "11".
- 3-Indolepropionic_acid casNumber "830".
- 3-Indolepropionic_acid chebi "43580".
- 3-Indolepropionic_acid chemspiderid "3613".
- 3-Indolepropionic_acid drugName "3".
- 3-Indolepropionic_acid eliminationHalfLife "-18000.0".
- 3-Indolepropionic_acid h "11".
- 3-Indolepropionic_acid iupacName "3".
- 3-Indolepropionic_acid iupharLigand "4709".
- 3-Indolepropionic_acid legalUnComment "Unscheduled".
- 3-Indolepropionic_acid legalUsComment "Unscheduled".
- 3-Indolepropionic_acid meltingHigh "135".
- 3-Indolepropionic_acid meltingPoint "134".
- 3-Indolepropionic_acid molecularWeight "189.21054".
- 3-Indolepropionic_acid n "1".
- 3-Indolepropionic_acid o "2".
- 3-Indolepropionic_acid pubchem "3744".
- 3-Indolepropionic_acid smiles "C1=CC=C2CCCCCO".
- 3-Indolepropionic_acid stdinchi "1".
- 3-Indolepropionic_acid stdinchikey "GOLXRNDWAUTYKT-UHFFFAOYSA-N".
- 3-Indolepropionic_acid synonyms "Conjugate base:".
- 3-Indolepropionic_acid synonyms "Indole-3-propionate".
- 3-Indolepropionic_acid tradename "Oxigon".
- 3-Indolepropionic_acid unii "JF49U1Q7KN".
- 3-Indolepropionic_acid verifiedrevid "685380927".
- 3-Indolepropionic_acid wikiPageUsesTemplate Template:Cascite.
- 3-Indolepropionic_acid wikiPageUsesTemplate Template:Chemspidercite.
- 3-Indolepropionic_acid wikiPageUsesTemplate Template:Drugbankcite.
- 3-Indolepropionic_acid wikiPageUsesTemplate Template:Ebicite.
- 3-Indolepropionic_acid wikiPageUsesTemplate Template:Infobox_drug.
- 3-Indolepropionic_acid wikiPageUsesTemplate Template:Keggcite.
- 3-Indolepropionic_acid wikiPageUsesTemplate Template:Reflist.
- 3-Indolepropionic_acid subject Category:Antioxidants.
- 3-Indolepropionic_acid subject Category:Indoles.
- 3-Indolepropionic_acid subject Category:Propionic_acids.
- 3-Indolepropionic_acid hypernym Antioxidant.
- 3-Indolepropionic_acid type ChemicalCompound.
- 3-Indolepropionic_acid type ChemicalSubstance.
- 3-Indolepropionic_acid type Drug.
- 3-Indolepropionic_acid type ChemicalObject.
- 3-Indolepropionic_acid type Thing.
- 3-Indolepropionic_acid type Q8386.
- 3-Indolepropionic_acid comment "3-Indolepropionic acid (IPA), or indole-3-propionic acid, is a potent neuroprotective antioxidant and plant auxin that is being studied for therapeutic use in Alzheimer's disease. It is endogenously produced within the human microbiome and detectable in humans only when the bacteria Clostridium sporogenes is present in the gastrointestinal tract. In individuals who lack C. sporogenes colonization, IPA is not detectable in the blood. In order to synthesize IPA, C.".
- 3-Indolepropionic_acid label "3-Indolepropionic acid".
- 3-Indolepropionic_acid sameAs Q21098993.
- 3-Indolepropionic_acid sameAs Q21098993.
- 3-Indolepropionic_acid wasDerivedFrom 3-Indolepropionic_acid?oldid=696459955.
- 3-Indolepropionic_acid depiction 3-Indolepropionic_acid_skeletal.svg.
- 3-Indolepropionic_acid isPrimaryTopicOf 3-Indolepropionic_acid.