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- 25I-NBOH abstract "25I-NBOH (NBOH-2CI, Cimbi-27) is a derivative of the phenethylamine derived hallucinogen 2C-I that was discovered in 2006 by a team at Purdue University. It acts as a potent agonist for the 5HT2A receptor, with a Ki of 0.061nM at the human 5HT2A receptor, similar to the better-known compound 25I-NBOMe, making it some twelve times the potency of 2C-I itself. In vitro tests showed this compound acted as an agonist but animal studies have not been reported. While the N-benzyl derivatives of 2C-I were significantly increased in binding activity to 5HT2A receptor fragments, compared to 2C-I, the N-benzyl derivatives of DOI were less active, compared to DOI.25I-NBOH is notable as one of the most selective agonist ligands for the 5-HT2A receptor with an EC50 value of 0.074 nM and more than 400x selectivity over the 5-HT2C receptor.".
- 25I-NBOH casNumber "919797-20-9".
- 25I-NBOH iupacName "2-((2-(4-iodo-2,5-dimethoxyphenyl)ethylamino)methyl)phenol".
- 25I-NBOH pubchem "10001761".
- 25I-NBOH thumbnail 2C-I-NBOH-skeletal.svg?width=300.
- 25I-NBOH wikiPageID "17256380".
- 25I-NBOH wikiPageLength "4681".
- 25I-NBOH wikiPageOutDegree "25".
- 25I-NBOH wikiPageRevisionID "707961543".
- 25I-NBOH wikiPageWikiLink 2,5-Dimethoxy-4-iodoamphetamine.
- 25I-NBOH wikiPageWikiLink 25B-NBOH.
- 25I-NBOH wikiPageWikiLink 25B-NBOMe.
- 25I-NBOH wikiPageWikiLink 25C-NBOH.
- 25I-NBOH wikiPageWikiLink 25C-NBOMe.
- 25I-NBOH wikiPageWikiLink 25I-NBF.
- 25I-NBOH wikiPageWikiLink 25I-NBMD.
- 25I-NBOH wikiPageWikiLink 25I-NBOMe.
- 25I-NBOH wikiPageWikiLink 25TFM-NBOMe.
- 25I-NBOH wikiPageWikiLink 2C-I.
- 25I-NBOH wikiPageWikiLink 2CBCB-NBOMe.
- 25I-NBOH wikiPageWikiLink 2CBFly-NBOMe.
- 25I-NBOH wikiPageWikiLink 5-HT2A_receptor.
- 25I-NBOH wikiPageWikiLink Agonist.
- 25I-NBOH wikiPageWikiLink Category:Designer_drugs.
- 25I-NBOH wikiPageWikiLink Category:Iodoarenes.
- 25I-NBOH wikiPageWikiLink Category:Psychedelic_phenethylamines.
- 25I-NBOH wikiPageWikiLink Category:Serotonin_receptor_agonists.
- 25I-NBOH wikiPageWikiLink Dissociation_constant.
- 25I-NBOH wikiPageWikiLink Phenethylamine.
- 25I-NBOH wikiPageWikiLink Purdue_University.
- 25I-NBOH wikiPageWikiLink Receptor_(biochemistry).
- 25I-NBOH wikiPageWikiLinkText "25I-NBOH".
- 25I-NBOH wikiPageWikiLinkText "2C-I-NBOH".
- 25I-NBOH c "17".
- 25I-NBOH casNumber "919797".
- 25I-NBOH chemspiderid "8177342".
- 25I-NBOH h "20".
- 25I-NBOH i "1".
- 25I-NBOH inchi "1".
- 25I-NBOH inchikey "FEUZHYRXGQTBRO-UHFFFAOYAP".
- 25I-NBOH iupacName "2".
- 25I-NBOH molecularWeight "413.249".
- 25I-NBOH n "1".
- 25I-NBOH o "3".
- 25I-NBOH pubchem "10001761".
- 25I-NBOH smiles "Oc2ccccc2CNCCccc1OC".
- 25I-NBOH stdinchi "1".
- 25I-NBOH stdinchikey "FEUZHYRXGQTBRO-UHFFFAOYSA-N".
- 25I-NBOH verifiedfields "changed".
- 25I-NBOH verifiedrevid "477215972".
- 25I-NBOH wikiPageUsesTemplate Template:Cascite.
- 25I-NBOH wikiPageUsesTemplate Template:Chemspidercite.
- 25I-NBOH wikiPageUsesTemplate Template:Drugbox.
- 25I-NBOH wikiPageUsesTemplate Template:Hallucinogen-stub.
- 25I-NBOH wikiPageUsesTemplate Template:Hallucinogenic_phenethylamines.
- 25I-NBOH wikiPageUsesTemplate Template:Reflist.
- 25I-NBOH wikiPageUsesTemplate Template:Serotonergics.
- 25I-NBOH wikiPageUsesTemplate Template:Stdinchicite.
- 25I-NBOH subject Category:Designer_drugs.
- 25I-NBOH subject Category:Iodoarenes.
- 25I-NBOH subject Category:Psychedelic_phenethylamines.
- 25I-NBOH subject Category:Serotonin_receptor_agonists.
- 25I-NBOH hypernym Derivative.
- 25I-NBOH type ChemicalSubstance.
- 25I-NBOH type Drug.
- 25I-NBOH type Dissociative.
- 25I-NBOH type Drug.
- 25I-NBOH type Organohalide.
- 25I-NBOH type Organoiodide.
- 25I-NBOH type Organohalide.
- 25I-NBOH type Organoiodide.
- 25I-NBOH type ChemicalObject.
- 25I-NBOH type Thing.
- 25I-NBOH type Q8386.
- 25I-NBOH comment "25I-NBOH (NBOH-2CI, Cimbi-27) is a derivative of the phenethylamine derived hallucinogen 2C-I that was discovered in 2006 by a team at Purdue University. It acts as a potent agonist for the 5HT2A receptor, with a Ki of 0.061nM at the human 5HT2A receptor, similar to the better-known compound 25I-NBOMe, making it some twelve times the potency of 2C-I itself. In vitro tests showed this compound acted as an agonist but animal studies have not been reported.".
- 25I-NBOH label "25I-NBOH".
- 25I-NBOH sameAs Q4632139.
- 25I-NBOH sameAs m.043nn2_.
- 25I-NBOH sameAs 25I-NBOH.
- 25I-NBOH sameAs 25I-NBOH.
- 25I-NBOH sameAs Q4632139.
- 25I-NBOH wasDerivedFrom 25I-NBOH?oldid=707961543.
- 25I-NBOH depiction 2C-I-NBOH-skeletal.svg.
- 25I-NBOH isPrimaryTopicOf 25I-NBOH.