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- 1,3-Beta-glucan_synthase abstract "1,3-Beta-glucan synthase is a glucosyltransferase enzyme involved in the generation of beta-glucan in fungi. It serves as a pharmacological target for antifungal drugs such as caspofungin, anidulafungin, and micafungin.The biosynthesis of disaccharides, oligosaccharides, and polysaccharides involves the action of hundreds of different glycosyltransferases. These enzymes catalyse the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. A classification of glycosyltransferases using nucleotide diphospho-sugar, nucleotide monophospho-sugar and sugar phosphates (EC 2.4.1.-.), and related proteins into distinct sequence-based families has been described. This classification is available on the CAZy (CArbohydrate-Active EnZymes) web site . The same three-dimensional fold is expected to occur within each of the families. Because 3-D structures are better conserved than sequences, several of the families defined on the basis of sequence similarities may have similar 3-D structures and, therefore, form 'clans'.This is the glycosyltransferase 48 family, which consists of various 1,3-beta-glucan synthase components including Gls1, Gls2, and Gls3 from yeast. 1,3-Beta-glucan synthase (EC 2.4.1.34.) also known as callose synthase catalyses the formation of a beta-1,3-glucan polymer that is a major component of the fungal cell wall. The reaction catalysed is:-UDP-glucose + {(1,3)-beta-D-glucosyl}(N) = UDP + {(1,3)-beta-D-glucosyl}(N+1).".
- 1,3-Beta-glucan_synthase ecNumber "2.4.1.34".
- 1,3-Beta-glucan_synthase wikiPageExternalLink www.cazy.org.
- 1,3-Beta-glucan_synthase wikiPageID "12931666".
- 1,3-Beta-glucan_synthase wikiPageLength "3522".
- 1,3-Beta-glucan_synthase wikiPageOutDegree "38".
- 1,3-Beta-glucan_synthase wikiPageRevisionID "699070765".
- 1,3-Beta-glucan_synthase wikiPageWikiLink Anidulafungin.
- 1,3-Beta-glucan_synthase wikiPageWikiLink Antifungal.
- 1,3-Beta-glucan_synthase wikiPageWikiLink Beta-glucan.
- 1,3-Beta-glucan_synthase wikiPageWikiLink Biomolecular_structure.
- 1,3-Beta-glucan_synthase wikiPageWikiLink Biosynthesis.
- 1,3-Beta-glucan_synthase wikiPageWikiLink Caspofungin.
- 1,3-Beta-glucan_synthase wikiPageWikiLink Catalysis.
- 1,3-Beta-glucan_synthase wikiPageWikiLink Category:EC_2.4.1.
- 1,3-Beta-glucan_synthase wikiPageWikiLink Category:Protein_families.
- 1,3-Beta-glucan_synthase wikiPageWikiLink Cell_wall.
- 1,3-Beta-glucan_synthase wikiPageWikiLink Cis-Regulatory_element.
- 1,3-Beta-glucan_synthase wikiPageWikiLink Conserved_sequence.
- 1,3-Beta-glucan_synthase wikiPageWikiLink Echinocandin.
- 1,3-Beta-glucan_synthase wikiPageWikiLink Enzyme.
- 1,3-Beta-glucan_synthase wikiPageWikiLink Fungus.
- 1,3-Beta-glucan_synthase wikiPageWikiLink Glucan.
- 1,3-Beta-glucan_synthase wikiPageWikiLink Glucosyltransferase.
- 1,3-Beta-glucan_synthase wikiPageWikiLink Glycosidic_bond.
- 1,3-Beta-glucan_synthase wikiPageWikiLink Glycosyltransferase.
- 1,3-Beta-glucan_synthase wikiPageWikiLink Micafungin.
- 1,3-Beta-glucan_synthase wikiPageWikiLink Moiety_(chemistry).
- 1,3-Beta-glucan_synthase wikiPageWikiLink Molecule.
- 1,3-Beta-glucan_synthase wikiPageWikiLink Nucleotide.
- 1,3-Beta-glucan_synthase wikiPageWikiLink Oligosaccharide.
- 1,3-Beta-glucan_synthase wikiPageWikiLink Phosphate.
- 1,3-Beta-glucan_synthase wikiPageWikiLink Polymer.
- 1,3-Beta-glucan_synthase wikiPageWikiLink Polysaccharide.
- 1,3-Beta-glucan_synthase wikiPageWikiLink Protein.
- 1,3-Beta-glucan_synthase wikiPageWikiLink Protein_folding.
- 1,3-Beta-glucan_synthase wikiPageWikiLink Saccharomyces_cerevisiae.
- 1,3-Beta-glucan_synthase wikiPageWikiLink Sequence.
- 1,3-Beta-glucan_synthase wikiPageWikiLink Sequence_(biology).
- 1,3-Beta-glucan_synthase wikiPageWikiLink Sugar.
- 1,3-Beta-glucan_synthase wikiPageWikiLink Synthase.
- 1,3-Beta-glucan_synthase wikiPageWikiLink Thromboxane-A_synthase.
- 1,3-Beta-glucan_synthase wikiPageWikiLinkText "1,3-Beta-glucan synthase".
- 1,3-Beta-glucan_synthase casNumber "9037".
- 1,3-Beta-glucan_synthase cazy "GT48".
- 1,3-Beta-glucan_synthase ecNumber "2.4".
- 1,3-Beta-glucan_synthase interpro "IPR003440".
- 1,3-Beta-glucan_synthase iubmbEcNumber "2".
- 1,3-Beta-glucan_synthase name "13".
- 1,3-Beta-glucan_synthase name "Glucan_synthase".
- 1,3-Beta-glucan_synthase pfam "PF02364".
- 1,3-Beta-glucan_synthase pfamClan "CL0111".
- 1,3-Beta-glucan_synthase symbol "Glucan_synthase".
- 1,3-Beta-glucan_synthase wikiPageUsesTemplate Template:EC_number.
- 1,3-Beta-glucan_synthase wikiPageUsesTemplate Template:Enzymes.
- 1,3-Beta-glucan_synthase wikiPageUsesTemplate Template:Glycosyltransferases.
- 1,3-Beta-glucan_synthase wikiPageUsesTemplate Template:Infobox_enzyme.
- 1,3-Beta-glucan_synthase wikiPageUsesTemplate Template:Infobox_protein_family.
- 1,3-Beta-glucan_synthase wikiPageUsesTemplate Template:InterPro_content.
- 1,3-Beta-glucan_synthase wikiPageUsesTemplate Template:MeshName.
- 1,3-Beta-glucan_synthase wikiPageUsesTemplate Template:Portal_bar.
- 1,3-Beta-glucan_synthase wikiPageUsesTemplate Template:Reflist.
- 1,3-Beta-glucan_synthase wikiPageUsesTemplate Template:Transferase-stub.
- 1,3-Beta-glucan_synthase subject Category:EC_2.4.1.
- 1,3-Beta-glucan_synthase subject Category:Protein_families.
- 1,3-Beta-glucan_synthase hypernym Enzyme.
- 1,3-Beta-glucan_synthase type Biomolecule.
- 1,3-Beta-glucan_synthase type Enzyme.
- 1,3-Beta-glucan_synthase type Protein.
- 1,3-Beta-glucan_synthase type Diacritic.
- 1,3-Beta-glucan_synthase type Redirect.
- 1,3-Beta-glucan_synthase type Thing.
- 1,3-Beta-glucan_synthase type Q206229.
- 1,3-Beta-glucan_synthase type Q8047.
- 1,3-Beta-glucan_synthase comment "1,3-Beta-glucan synthase is a glucosyltransferase enzyme involved in the generation of beta-glucan in fungi. It serves as a pharmacological target for antifungal drugs such as caspofungin, anidulafungin, and micafungin.The biosynthesis of disaccharides, oligosaccharides, and polysaccharides involves the action of hundreds of different glycosyltransferases.".
- 1,3-Beta-glucan_synthase label "1,3-Beta-glucan synthase".
- 1,3-Beta-glucan_synthase sameAs Q3596746.
- 1,3-Beta-glucan_synthase sameAs 1,3-beta-glucano_sintasi.
- 1,3-Beta-glucan_synthase sameAs m.02z0cmb.
- 1,3-Beta-glucan_synthase sameAs 1,3-b-glukan_sintaza.
- 1,3-Beta-glucan_synthase sameAs 1,3-b-glukan_sintaza.
- 1,3-Beta-glucan_synthase sameAs Q3596746.
- 1,3-Beta-glucan_synthase wasDerivedFrom 1,3-Beta-glucan_synthase?oldid=699070765.
- 1,3-Beta-glucan_synthase isPrimaryTopicOf 1,3-Beta-glucan_synthase.
- 1,3-Beta-glucan_synthase name "1,3-Beta-glucan synthase".