Matches in DBpedia 2016-04 for { ?s ?p "Butyrophenone is a chemical compound; some of its derivatives (called commonly butyrophenones) are used to treat various psychiatric disorders such as schizophrenia, as well as acting as antiemetics.Butyrophenones are a class of pharmaceutical drugs derived from butyrophenone.Examples include: Haloperidol, the most widely used classical antipsychotic drug in this class Droperidol, often used for neuroleptanalgesic anesthesia and sedation in intensive-care treatment Benperidol, the most potent commonly used antipsychotic ( 200 times more potent than chlorpromazine) Trifluperidol, a highly potent antipsychotic (100 times more potent than chlorpromazine) Melperone, a weakly potent antipsychotic, in Europe commonly used for treatment of insomnia, confusional states, psychomotor agitation, and delirium, in particular, in geriatric patients Lenperone Azaperone, used in veterinary medicine Domperidone, a dopamine-antagonist antiemetic, derived further from butyrophenone (not being a butyrophenone itself). Fluanisone Penfluridol Pipamperone Spiperone (more potent neuroleptic than benperidol) NonaperoneCloroperoneThe atypical antipsychotic risperidone, although not a butyrophenone, was developed with the structures of benperidol and ketanserin as a basis.Ketocaine is a butyrophenone local anesthetic.Fluspiperone is the butyrophenone equivalent of the diphenylbutylpiperidine based antipsychotic FluspirileneIn the case of Spirilene, the butyrophenone is methylated with one equivalent of Grignard reagent and the corresponding tertiary alcohol is then dehydrated to an olefin.Halopemide is similar to a butyrophenone antipsychotic in which the methylene carbon closest to the carbonyl is replaced with a secondary nitrogen so that the structure become benzamide based.↑ 1.0 1.1 1.2 ↑ ↑ ↑"@en }
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- Butyrophenone abstract "Butyrophenone is a chemical compound; some of its derivatives (called commonly butyrophenones) are used to treat various psychiatric disorders such as schizophrenia, as well as acting as antiemetics.Butyrophenones are a class of pharmaceutical drugs derived from butyrophenone.Examples include: Haloperidol, the most widely used classical antipsychotic drug in this class Droperidol, often used for neuroleptanalgesic anesthesia and sedation in intensive-care treatment Benperidol, the most potent commonly used antipsychotic ( 200 times more potent than chlorpromazine) Trifluperidol, a highly potent antipsychotic (100 times more potent than chlorpromazine) Melperone, a weakly potent antipsychotic, in Europe commonly used for treatment of insomnia, confusional states, psychomotor agitation, and delirium, in particular, in geriatric patients Lenperone Azaperone, used in veterinary medicine Domperidone, a dopamine-antagonist antiemetic, derived further from butyrophenone (not being a butyrophenone itself). Fluanisone Penfluridol Pipamperone Spiperone (more potent neuroleptic than benperidol) NonaperoneCloroperoneThe atypical antipsychotic risperidone, although not a butyrophenone, was developed with the structures of benperidol and ketanserin as a basis.Ketocaine is a butyrophenone local anesthetic.Fluspiperone is the butyrophenone equivalent of the diphenylbutylpiperidine based antipsychotic FluspirileneIn the case of Spirilene, the butyrophenone is methylated with one equivalent of Grignard reagent and the corresponding tertiary alcohol is then dehydrated to an olefin.Halopemide is similar to a butyrophenone antipsychotic in which the methylene carbon closest to the carbonyl is replaced with a secondary nitrogen so that the structure become benzamide based.↑ 1.0 1.1 1.2 ↑ ↑ ↑".
- Q421344 abstract "Butyrophenone is a chemical compound; some of its derivatives (called commonly butyrophenones) are used to treat various psychiatric disorders such as schizophrenia, as well as acting as antiemetics.Butyrophenones are a class of pharmaceutical drugs derived from butyrophenone.Examples include: Haloperidol, the most widely used classical antipsychotic drug in this class Droperidol, often used for neuroleptanalgesic anesthesia and sedation in intensive-care treatment Benperidol, the most potent commonly used antipsychotic ( 200 times more potent than chlorpromazine) Trifluperidol, a highly potent antipsychotic (100 times more potent than chlorpromazine) Melperone, a weakly potent antipsychotic, in Europe commonly used for treatment of insomnia, confusional states, psychomotor agitation, and delirium, in particular, in geriatric patients Lenperone Azaperone, used in veterinary medicine Domperidone, a dopamine-antagonist antiemetic, derived further from butyrophenone (not being a butyrophenone itself). Fluanisone Penfluridol Pipamperone Spiperone (more potent neuroleptic than benperidol) NonaperoneCloroperoneThe atypical antipsychotic risperidone, although not a butyrophenone, was developed with the structures of benperidol and ketanserin as a basis.Ketocaine is a butyrophenone local anesthetic.Fluspiperone is the butyrophenone equivalent of the diphenylbutylpiperidine based antipsychotic FluspirileneIn the case of Spirilene, the butyrophenone is methylated with one equivalent of Grignard reagent and the corresponding tertiary alcohol is then dehydrated to an olefin.Halopemide is similar to a butyrophenone antipsychotic in which the methylene carbon closest to the carbonyl is replaced with a secondary nitrogen so that the structure become benzamide based.↑ 1.0 1.1 1.2 ↑ ↑ ↑".