Matches in DBpedia 2015-10 for { <http://dbpedia.org/resource/WWTR1> ?p ?o }
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- WWTR1 abstract "WW domain-containing transcription regulator protein 1 is a protein that in humans is encoded by the WWTR1 gene.It is a transcriptional coactivator which acts as a downstream regulatory target in the Hippo signaling pathway thatplays a pivotal role in organ size control and tumor suppression by restricting proliferation and promoting apoptosis.The core of this pathway is composed of a kinase cascade wherein MST1/MST2, in complex with its regulatory proteinSAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1, which in turn phosphorylatesand inactivates YAP1 oncoprotein and WWTR1/TAZ. WWTR1 enhances PAX8 and NKX2-1/TTF1-dependent gene activation.Regulates the nuclear accumulation of SMADS and has a key role in coupling them to the transcriptional machinery suchas the mediator complex.".
- WWTR1 entrezgene "25937".
- WWTR1 wikiPageID "16848763".
- WWTR1 wikiPageLength "4174".
- WWTR1 wikiPageOutDegree "2".
- WWTR1 wikiPageRevisionID "679114133".
- WWTR1 wikiPageWikiLink Gene.
- WWTR1 wikiPageWikiLink Protein.
- WWTR1 wikiPageWikiLinkText "TAZ".
- WWTR1 wikiPageWikiLinkText "WWTR1".
- WWTR1 hasPhotoCollection WWTR1.
- WWTR1 requireManualInspection "no".
- WWTR1 updateCitations "yes".
- WWTR1 updatePage "yes".
- WWTR1 updateProteinBox "yes".
- WWTR1 updateSummary "yes".
- WWTR1 wikiPageUsesTemplate Template:Gene-3-stub.
- WWTR1 wikiPageUsesTemplate Template:PBB.
- WWTR1 wikiPageUsesTemplate Template:PBB_Controls.
- WWTR1 wikiPageUsesTemplate Template:PBB_Further_reading.
- WWTR1 wikiPageUsesTemplate Template:PBB_Summary.
- WWTR1 wikiPageUsesTemplate Template:Refbegin.
- WWTR1 wikiPageUsesTemplate Template:Refend.
- WWTR1 wikiPageUsesTemplate Template:Reflist.
- WWTR1 hypernym Protein.
- WWTR1 type Biomolecule.
- WWTR1 type Protein.
- WWTR1 type Thing.
- WWTR1 type Q206229.
- WWTR1 type Q8054.
- WWTR1 comment "WW domain-containing transcription regulator protein 1 is a protein that in humans is encoded by the WWTR1 gene.It is a transcriptional coactivator which acts as a downstream regulatory target in the Hippo signaling pathway thatplays a pivotal role in organ size control and tumor suppression by restricting proliferation and promoting apoptosis.The core of this pathway is composed of a kinase cascade wherein MST1/MST2, in complex with its regulatory proteinSAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1, which in turn phosphorylatesand inactivates YAP1 oncoprotein and WWTR1/TAZ. ".
- WWTR1 label "WWTR1".
- WWTR1 sameAs m.04087r0.
- WWTR1 sameAs Q7957490.
- WWTR1 sameAs Q7957490.
- WWTR1 wasDerivedFrom WWTR1?oldid=679114133.
- WWTR1 isPrimaryTopicOf WWTR1.