Matches in DBpedia 2015-10 for { <http://dbpedia.org/resource/Vpu> ?p ?o }
Showing triples 1 to 95 of
95
with 100 triples per page.
- Vpu abstract "Vpu is a protein that in HIV is encoded by the vpu gene. Vpu stands for "Viral Protein Unique". The Vpu protein acts in the degradation of CD4 in the endoplasmic reticulum and in the enhancement of virion release from the plasma membrane of infected cells. Vpu induces the degradation of the CD4 viral receptor and therefore participates in the general downregulation of CD4 expression during the course of HIV infection. Vpu-mediated CD4 degradation is thought to prevent CD4-Env binding in the endoplasmic reticulum in order to facilitate proper Env assembly into virions. It is found in the membranes of infected cells, but not the virus particles themselves.The Vpu gene is found exclusively in HIV-1 and some HIV-1-related simian immunodeficiency virus (SIV) isolates, such as SIVcpz, SIVgsn, and SIVmon, but not in HIV-2 or the majority of SIV isolates. Structural similarities between Vpu and another small viral protein, M2, encoded by influenza A virus were first noted soon after the discovery of Vpu. Since then, M2 has been shown to form cation-selective ion channels when expressed in Xenopus oocytes or mammalian cells and also when purified and reconstituted into planar lipid bilayers.".
- Vpu symbol "Vpu".
- Vpu thumbnail PDB_1pje_EBI.jpg?width=300.
- Vpu wikiPageID "17707387".
- Vpu wikiPageLength "10496".
- Vpu wikiPageOutDegree "37".
- Vpu wikiPageRevisionID "683743186".
- Vpu wikiPageWikiLink Alpha_helix.
- Vpu wikiPageWikiLink BST2.
- Vpu wikiPageWikiLink C-terminal.
- Vpu wikiPageWikiLink C-terminus.
- Vpu wikiPageWikiLink CD4.
- Vpu wikiPageWikiLink AIDS.
- Vpu wikiPageWikiLink Category:Protein_domains.
- Vpu wikiPageWikiLink Category:Viral_proteins.
- Vpu wikiPageWikiLink Cell_(biology).
- Vpu wikiPageWikiLink Cell_membrane.
- Vpu wikiPageWikiLink Cytoplasm.
- Vpu wikiPageWikiLink Cytoplasmic.
- Vpu wikiPageWikiLink Endoplasmic_reticulum.
- Vpu wikiPageWikiLink Env_(gene).
- Vpu wikiPageWikiLink Gene.
- Vpu wikiPageWikiLink Glycophosphatidylinositol.
- Vpu wikiPageWikiLink Glycosylated.
- Vpu wikiPageWikiLink Glycosylation.
- Vpu wikiPageWikiLink Glycosylphosphatidylinositol.
- Vpu wikiPageWikiLink HIV.
- Vpu wikiPageWikiLink Initiation_codon.
- Vpu wikiPageWikiLink Integral_membrane_protein.
- Vpu wikiPageWikiLink Interferon.
- Vpu wikiPageWikiLink Ion_channel.
- Vpu wikiPageWikiLink Lipid_raft.
- Vpu wikiPageWikiLink Messenger_RNA.
- Vpu wikiPageWikiLink Model_lipid_bilayer.
- Vpu wikiPageWikiLink N-terminus.
- Vpu wikiPageWikiLink Proteasome.
- Vpu wikiPageWikiLink Protein.
- Vpu wikiPageWikiLink Ribosome.
- Vpu wikiPageWikiLink Simian_immunodeficiency_virus.
- Vpu wikiPageWikiLink Start_codon.
- Vpu wikiPageWikiLink Structure_and_genome_of_HIV.
- Vpu wikiPageWikiLink Tetherin.
- Vpu wikiPageWikiLink Transmembrane_domain.
- Vpu wikiPageWikiLink Virion.
- Vpu wikiPageWikiLink Virus.
- Vpu wikiPageWikiLink Xenopus.
- Vpu wikiPageWikiLinkText "Vpu".
- Vpu wikiPageWikiLinkText "vpu".
- Vpu caption "structure of the channel-forming trans-membrane domain of virus protein "u" from HIV-1".
- Vpu chromosome "viral genome".
- Vpu entrezchromosome "NC_001802.1".
- Vpu entrezgene "155945".
- Vpu genlocEnd "5892".
- Vpu genlocStart "5570".
- Vpu hasPhotoCollection Vpu.
- Vpu interpro "IPR008187".
- Vpu name "Viral Protein Unique".
- Vpu name "Vpu".
- Vpu organism "HIV-1".
- Vpu pfam "PF00558".
- Vpu refseqprotein "NP_057855.1".
- Vpu scop "1".
- Vpu symbol "Vpu".
- Vpu symbol "vpu".
- Vpu taxid "11676".
- Vpu tcdb "1".
- Vpu uniprot "Q9WB91".
- Vpu wikiPageUsesTemplate Template:Infobox_nonhuman_protein.
- Vpu wikiPageUsesTemplate Template:Infobox_protein_family.
- Vpu wikiPageUsesTemplate Template:InterPro_content.
- Vpu wikiPageUsesTemplate Template:MeshName.
- Vpu wikiPageUsesTemplate Template:Reflist.
- Vpu wikiPageUsesTemplate Template:Sub.
- Vpu wikiPageUsesTemplate Template:Viral_proteins.
- Vpu subject AIDS.
- Vpu subject Category:Protein_domains.
- Vpu subject Category:Viral_proteins.
- Vpu hypernym Protein.
- Vpu type Article.
- Vpu type Biomolecule.
- Vpu type Protein.
- Vpu type Article.
- Vpu type Chemical.
- Vpu type Domain.
- Vpu type Thing.
- Vpu type Q206229.
- Vpu type Q8054.
- Vpu comment "Vpu is a protein that in HIV is encoded by the vpu gene. Vpu stands for "Viral Protein Unique". The Vpu protein acts in the degradation of CD4 in the endoplasmic reticulum and in the enhancement of virion release from the plasma membrane of infected cells. Vpu induces the degradation of the CD4 viral receptor and therefore participates in the general downregulation of CD4 expression during the course of HIV infection.".
- Vpu label "Vpu".
- Vpu sameAs m.05b6q1d.
- Vpu sameAs Q7942549.
- Vpu sameAs Q7942549.
- Vpu wasDerivedFrom Vpu?oldid=683743186.
- Vpu depiction PDB_1pje_EBI.jpg.
- Vpu isPrimaryTopicOf Vpu.