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- Vasotocin abstract "Vasotocin is an oligopeptide homologous to oxytocin and vasopressin found in all non-mammalian vertebrates (including birds, fishes, and amphibians) and possibly in mammals during the fetal stage of development. Arginine vasotocin (AVT), a hormone produced by neurosecretory cells within the posterior pituitary gland (neurohypophysis) of the brain, is a major endocrine regulator of water balance and osmotic homoeostasis and is involved in social and sexual behavior in non-mammalian vertebrates. In mammals, it appears to have biological properties similar to those of oxytocin (stimulating reproductive tract contraction as in egg laying or birth) and vasopressin (diuretic and antidiuretic effects). It has been found to have effects on the regulation of REM sleep. Evidence for the existence of endogenous vasotocin in mammals is limited and no mammalian gene encoding vasotocin has been confirmed.AVT (Cys-Tyr-Ile-Gln-Asn-Cys-Pro-Arg-Gly-NH2), which occurs in the lamprey, represents the ancestral form in the phylogeny of the vertebrate neurohypophysial hormones. Gene duplication and point mutation have produced two distinct lineages, one involved in reproduction (oxytocin-like peptides) and the other in osmoregulation (vasopressin-like peptides). These hormones have remained highly conserved throughout evolution. Each is a peptide of nine amino acids derived from a preprohormone precursor by proteolytic cleavage, with an intramolecular disulfide bridge between the cysteine (Cys) residues; the C-terminal glycine (Gly) residue is amidated. Six of the residues have been found to be invariant in homologous peptides from numerous species of vertebrates. The vasopressin-like peptides, which differ in positions 3 and/or 8, include AVT and the mammalian hormones arginine vasopressin (Cys-Tyr-Phe-Gln-Asn-Cys-Pro-Arg-Gly-NH2, with isoleucine-3 of AVT changed to phenylalanine) and lysine vasopressin (isoleucine-3 changed to phenylalanine and arginine-8 changed to lysine). The oxytocin-like peptides, which differ in positions 4 and/or 8, include oxytocin (Cys-Tyr-Ile-Gln-Asn-Cys-Pro-Leu-Gly-NH2, with arginine-8 of AVT changed to leucine), mesotocin (arginine-8 changed to isoleucine), and isotocin (glutamine-4 changed to serine and arginine-8 changed to isoleucine); they differ from the vasopressin-like peptides in having a neutral amino acid in place of a basic amino acid at position 8. Oxytocin occurs in placental mammals; mesotocin occurs in amphibians, reptiles, and birds, and isotocin occurs in fishes.".
- Vasotocin iupacName "1-[(1R,4S,7S,13S,16R)-16-amino-4-(2-amino-2-oxoethyl)-7-(3-amino-3-oxopropyl)-10-[(2S)-butan-2-yl]-13-[(4-hydroxyphenyl)methyl]-3,6,9,12,15-pentaoxo-18,19-dithia-2,5,8,11,14-pentazacycloicosane-1-carbonyl]-N-[(2S)-1-[(2-amino-2-oxoethyl)amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]pyrrolidine-2-carboxamide".
- Vasotocin thumbnail Vasotocin.png?width=300.
- Vasotocin wikiPageID "7337156".
- Vasotocin wikiPageLength "10260".
- Vasotocin wikiPageOutDegree "42".
- Vasotocin wikiPageRevisionID "667303062".
- Vasotocin wikiPageWikiLink Aggression.
- Vasotocin wikiPageWikiLink Amphibian.
- Vasotocin wikiPageWikiLink Arginine.
- Vasotocin wikiPageWikiLink Arginine_vasopressin.
- Vasotocin wikiPageWikiLink Bird.
- Vasotocin wikiPageWikiLink Category:Neuropeptides.
- Vasotocin wikiPageWikiLink Category:Oxytocin_receptor_agonists.
- Vasotocin wikiPageWikiLink Category:Vasopressin_receptor_agonists.
- Vasotocin wikiPageWikiLink Chum_salmon.
- Vasotocin wikiPageWikiLink Coral_reef.
- Vasotocin wikiPageWikiLink Cysteine.
- Vasotocin wikiPageWikiLink Finch.
- Vasotocin wikiPageWikiLink Fish.
- Vasotocin wikiPageWikiLink Glutamine.
- Vasotocin wikiPageWikiLink Glycine.
- Vasotocin wikiPageWikiLink Hypothalamus.
- Vasotocin wikiPageWikiLink Isoleucine.
- Vasotocin wikiPageWikiLink Isotocin.
- Vasotocin wikiPageWikiLink Japanese_quail.
- Vasotocin wikiPageWikiLink Lamprey.
- Vasotocin wikiPageWikiLink Leucine.
- Vasotocin wikiPageWikiLink Lysine.
- Vasotocin wikiPageWikiLink Lysine_vasopressin.
- Vasotocin wikiPageWikiLink Mesotocin.
- Vasotocin wikiPageWikiLink Neurophysins.
- Vasotocin wikiPageWikiLink Oligopeptide.
- Vasotocin wikiPageWikiLink Osmoregulation.
- Vasotocin wikiPageWikiLink Oxytocin.
- Vasotocin wikiPageWikiLink Pair_bond.
- Vasotocin wikiPageWikiLink Pair_bonding.
- Vasotocin wikiPageWikiLink Phenylalanine.
- Vasotocin wikiPageWikiLink Posterior_pituitary.
- Vasotocin wikiPageWikiLink Quail.
- Vasotocin wikiPageWikiLink Rainbow_Trout.
- Vasotocin wikiPageWikiLink Rainbow_trout.
- Vasotocin wikiPageWikiLink Rapid_eye_movement_sleep.
- Vasotocin wikiPageWikiLink Serine.
- Vasotocin wikiPageWikiLink Social_hierarchy.
- Vasotocin wikiPageWikiLink Social_stratification.
- Vasotocin wikiPageWikiLink Vasopressin.
- Vasotocin wikiPageWikiLink Zebra_finch.
- Vasotocin wikiPageWikiLinkText "Vasotocin".
- Vasotocin wikiPageWikiLinkText "vasotocin".
- Vasotocin hasPhotoCollection Vasotocin.
- Vasotocin imagefile "vasotocin.png".
- Vasotocin imagesize "250".
- Vasotocin iupacname "1".
- Vasotocin othernames "Argiprestocin; Arg-vasotocin; 8-Arg-vasotocin; Arginine vasotocin".
- Vasotocin verifiedfields "changed".
- Vasotocin verifiedrevid "441829086".
- Vasotocin wikiPageUsesTemplate Template:Chembox.
- Vasotocin wikiPageUsesTemplate Template:MeshName.
- Vasotocin wikiPageUsesTemplate Template:Neuropeptidergics.
- Vasotocin wikiPageUsesTemplate Template:Reflist.
- Vasotocin subject Category:Neuropeptides.
- Vasotocin subject Category:Oxytocin_receptor_agonists.
- Vasotocin subject Category:Vasopressin_receptor_agonists.
- Vasotocin hypernym Oligopeptide.
- Vasotocin type Article.
- Vasotocin type ChemicalCompound.
- Vasotocin type ChemicalSubstance.
- Vasotocin type Article.
- Vasotocin type Chemical.
- Vasotocin type Hormone.
- Vasotocin type Neuropeptide.
- Vasotocin type ChemicalObject.
- Vasotocin type Thing.
- Vasotocin type Q11173.
- Vasotocin comment "Vasotocin is an oligopeptide homologous to oxytocin and vasopressin found in all non-mammalian vertebrates (including birds, fishes, and amphibians) and possibly in mammals during the fetal stage of development. Arginine vasotocin (AVT), a hormone produced by neurosecretory cells within the posterior pituitary gland (neurohypophysis) of the brain, is a major endocrine regulator of water balance and osmotic homoeostasis and is involved in social and sexual behavior in non-mammalian vertebrates.".
- Vasotocin label "Vasotocin".
- Vasotocin sameAs وازوتوسین.
- Vasotocin sameAs 바소토신.
- Vasotocin sameAs Wazotocyna.
- Vasotocin sameAs m.025zl9x.
- Vasotocin sameAs Vazotocin.
- Vasotocin sameAs Vazotocin.
- Vasotocin sameAs Q871349.
- Vasotocin sameAs Q871349.
- Vasotocin wasDerivedFrom Vasotocin?oldid=667303062.
- Vasotocin depiction Vasotocin.png.
- Vasotocin isPrimaryTopicOf Vasotocin.