Matches in DBpedia 2015-10 for { <http://dbpedia.org/resource/Vascular_remodelling_in_the_embryo> ?p ?o }
- Vascular_remodelling_in_the_embryo abstract "Vascular remodelling is a process which begins at day 21 of human embryogenesis, when an immature heart begins contracting, pushing fluid through the early vasculature. This first passage of fluid initiates a signal cascade based on physical cues including shear stress and circumferential stress, which is necessary for the remodelling of the vascular network, arterial-venous identity, angiogenesis, and the regulation of genes through mechanotransduction. This embryonic process is necessary for the future stability of the mature vascular network.Vasculogenesis is the initial establishment of the components of the blood vessel network, or vascular tree. This is dictated by genetic factors and has no inherent function other than to lay down the preliminary outline of the circulatory system. Once fluid flow begins, biomechanical and hemodynamic inputs are applied to the system set up by vasculogenesis, and the active remodelling process can begin.Physical cues such as pressure, velocity, flow patterns, and shear stress are known to act on the vascular network in a number of ways, including branching morphogenesis, enlargement of vessels in high-flow areas, angiogenesis, and the development of vein valves. The mechanotransduction of these physical cues to endothelial and smooth muscle cells in the vascular wall can also trigger the promotion or repression of certain genes which are responsible for vasodilation, cell alignment, and other shear stress-mitigating factors. This relationship between genetics and environment is not clearly understood, but researchers are attempting to clarify it by combining reliable genetic techniques, such as genetically-ablated model organisms and tissues, with new technologies developed to measure and track flow patterns, velocity profiles, and pressure fluctuations in vivo.Both in vivo study and modelling are necessary tools to understand this complex process. Vascular remodelling is pertinent to wound healing and proper integration of tissue grafts and organ donations. Promoting an active remodelling process in some cases could help patients recover faster and retain functional use of donated tissues. However, outside of wound healing, chronic vascular remodelling in the adult is often symptomatic of cardiovascular disease. Thus, increased understanding of this biomedical phenomenon could aid in the development of therapeutics or preventative measures to combat diseases such as atherosclerosis.".
- Vascular_remodelling_in_the_embryo thumbnail Stages_of_vascular_development.png?width=300.
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- Vascular_remodelling_in_the_embryo wikiPageRevisionID "654582662".
- Vascular_remodelling_in_the_embryo wikiPageWikiLink Actin.
- Vascular_remodelling_in_the_embryo wikiPageWikiLink Acute_(medicine).
- Vascular_remodelling_in_the_embryo wikiPageWikiLink Adaptation.
- Vascular_remodelling_in_the_embryo wikiPageWikiLink Adapted.
- Vascular_remodelling_in_the_embryo wikiPageWikiLink Alan_Turing.
- Vascular_remodelling_in_the_embryo wikiPageWikiLink Anatomical_terms_of_location.
- Vascular_remodelling_in_the_embryo wikiPageWikiLink Angioblast.
- Vascular_remodelling_in_the_embryo wikiPageWikiLink Angioblasts.
- Vascular_remodelling_in_the_embryo wikiPageWikiLink Angiogenesis.
- Vascular_remodelling_in_the_embryo wikiPageWikiLink Aorta.
- Vascular_remodelling_in_the_embryo wikiPageWikiLink Apoptosis.
- Vascular_remodelling_in_the_embryo wikiPageWikiLink Artery.
- Vascular_remodelling_in_the_embryo wikiPageWikiLink Asymmetry.
- Vascular_remodelling_in_the_embryo wikiPageWikiLink Atherosclerosis.
- Vascular_remodelling_in_the_embryo wikiPageWikiLink Biomechanics.
- Vascular_remodelling_in_the_embryo wikiPageWikiLink Biomedical.
- Vascular_remodelling_in_the_embryo wikiPageWikiLink Blood_gas_tension.
- Vascular_remodelling_in_the_embryo wikiPageWikiLink Blood_islands.
- Vascular_remodelling_in_the_embryo wikiPageWikiLink Blood_plasma.
- Vascular_remodelling_in_the_embryo wikiPageWikiLink Blood_vessel.
- Vascular_remodelling_in_the_embryo wikiPageWikiLink Boundary_layer.
- Vascular_remodelling_in_the_embryo wikiPageWikiLink Boundary_layers.
- Vascular_remodelling_in_the_embryo wikiPageWikiLink Capillary.
- Vascular_remodelling_in_the_embryo wikiPageWikiLink Capillary_beds.
- Vascular_remodelling_in_the_embryo wikiPageWikiLink Cardiac_vein.
- Vascular_remodelling_in_the_embryo wikiPageWikiLink Cardiovascular_disease.
- Vascular_remodelling_in_the_embryo wikiPageWikiLink Category:Embryology.
- Vascular_remodelling_in_the_embryo wikiPageWikiLink Cell_(biology).
- Vascular_remodelling_in_the_embryo wikiPageWikiLink Cell_adhesion.
- Vascular_remodelling_in_the_embryo wikiPageWikiLink Cell_fusion.
- Vascular_remodelling_in_the_embryo wikiPageWikiLink Cell_growth.
- Vascular_remodelling_in_the_embryo wikiPageWikiLink Cellular_differentiation.
- Vascular_remodelling_in_the_embryo wikiPageWikiLink Chicken.
- Vascular_remodelling_in_the_embryo wikiPageWikiLink Chronic_(medicine).
- Vascular_remodelling_in_the_embryo wikiPageWikiLink Chronic_condition.
- Vascular_remodelling_in_the_embryo wikiPageWikiLink Circulatory_system.
- Vascular_remodelling_in_the_embryo wikiPageWikiLink Circumferential_stress.
- Vascular_remodelling_in_the_embryo wikiPageWikiLink Compression_(physical).
- Vascular_remodelling_in_the_embryo wikiPageWikiLink Compression_(physics).
- Vascular_remodelling_in_the_embryo wikiPageWikiLink Computer_scientist.
- Vascular_remodelling_in_the_embryo wikiPageWikiLink Coronary_circulation.
- Vascular_remodelling_in_the_embryo wikiPageWikiLink Cylinder_stress.
- Vascular_remodelling_in_the_embryo wikiPageWikiLink Cytoskeleton.
- Vascular_remodelling_in_the_embryo wikiPageWikiLink DLL4.
- Vascular_remodelling_in_the_embryo wikiPageWikiLink Deformation_(mechanics).
- Vascular_remodelling_in_the_embryo wikiPageWikiLink Diameter.
- Vascular_remodelling_in_the_embryo wikiPageWikiLink Dielectric_breakdown_model.
- Vascular_remodelling_in_the_embryo wikiPageWikiLink Diffusion-limited_aggregation.
- Vascular_remodelling_in_the_embryo wikiPageWikiLink Dorsal_aorta.
- Vascular_remodelling_in_the_embryo wikiPageWikiLink Downregulation_and_upregulation.
- Vascular_remodelling_in_the_embryo wikiPageWikiLink EPHB4.
- Vascular_remodelling_in_the_embryo wikiPageWikiLink EPH_receptor_B4.
- Vascular_remodelling_in_the_embryo wikiPageWikiLink Embryo.
- Vascular_remodelling_in_the_embryo wikiPageWikiLink Endothelial.
- Vascular_remodelling_in_the_embryo wikiPageWikiLink Endothelial_NOS.
- Vascular_remodelling_in_the_embryo wikiPageWikiLink Endothelial_nitric_oxide_synthase.
- Vascular_remodelling_in_the_embryo wikiPageWikiLink Endothelium.
- Vascular_remodelling_in_the_embryo wikiPageWikiLink Environment_(systems).
- Vascular_remodelling_in_the_embryo wikiPageWikiLink Ephrin_receptor.
- Vascular_remodelling_in_the_embryo wikiPageWikiLink Ephrins.
- Vascular_remodelling_in_the_embryo wikiPageWikiLink Epithelial_cells.
- Vascular_remodelling_in_the_embryo wikiPageWikiLink Epithelium.
- Vascular_remodelling_in_the_embryo wikiPageWikiLink Erythrocytes.
- Vascular_remodelling_in_the_embryo wikiPageWikiLink Evolution.
- Vascular_remodelling_in_the_embryo wikiPageWikiLink Extracellular_matrix.
- Vascular_remodelling_in_the_embryo wikiPageWikiLink Extrusion.
- Vascular_remodelling_in_the_embryo wikiPageWikiLink Feedback.
- Vascular_remodelling_in_the_embryo wikiPageWikiLink Feedback_loops.
- Vascular_remodelling_in_the_embryo wikiPageWikiLink Fluid_dynamics.
- Vascular_remodelling_in_the_embryo wikiPageWikiLink Fractal.
- Vascular_remodelling_in_the_embryo wikiPageWikiLink Friction.
- Vascular_remodelling_in_the_embryo wikiPageWikiLink Gene.
- Vascular_remodelling_in_the_embryo wikiPageWikiLink Genetic_marker.
- Vascular_remodelling_in_the_embryo wikiPageWikiLink Genetic_markers.
- Vascular_remodelling_in_the_embryo wikiPageWikiLink Genetics.
- Vascular_remodelling_in_the_embryo wikiPageWikiLink Glycocalyx.
- Vascular_remodelling_in_the_embryo wikiPageWikiLink Graft_(surgery).
- Vascular_remodelling_in_the_embryo wikiPageWikiLink Heart.
- Vascular_remodelling_in_the_embryo wikiPageWikiLink Heart_rate.
- Vascular_remodelling_in_the_embryo wikiPageWikiLink Hemangioblast.
- Vascular_remodelling_in_the_embryo wikiPageWikiLink Hemangioblasts.
- Vascular_remodelling_in_the_embryo wikiPageWikiLink Hematocrit.
- Vascular_remodelling_in_the_embryo wikiPageWikiLink Hemodynamic.
- Vascular_remodelling_in_the_embryo wikiPageWikiLink Hemodynamics.
- Vascular_remodelling_in_the_embryo wikiPageWikiLink Heterogeneous.
- Vascular_remodelling_in_the_embryo wikiPageWikiLink Homeostasis.
- Vascular_remodelling_in_the_embryo wikiPageWikiLink Homeostatic.
- Vascular_remodelling_in_the_embryo wikiPageWikiLink Homogeneity_and_heterogeneity.
- Vascular_remodelling_in_the_embryo wikiPageWikiLink Human_development_(biology).
- Vascular_remodelling_in_the_embryo wikiPageWikiLink Human_embryogenesis.
- Vascular_remodelling_in_the_embryo wikiPageWikiLink Hyperaemia.
- Vascular_remodelling_in_the_embryo wikiPageWikiLink Hypoxia-inducible_factors.
- Vascular_remodelling_in_the_embryo wikiPageWikiLink Hypoxia_(medical).
- Vascular_remodelling_in_the_embryo wikiPageWikiLink Hypoxia_inducible_factor.