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- Umespirone abstract "Umespirone (KC-9172) is a drug of the azapirone class which possesses anxiolytic and antipsychotic properties. It behaves as a 5-HT1A receptor partial agonist (Ki = 15 nM), D2 receptor partial agonist (Ki = 23 nM), and α1-adrenoceptor receptor antagonist (Ki = 14 nM), and also has weak affinity for the sigma receptor (Ki = 558 nM). Unlike many other anxiolytics and antipsychotics, umespirone produces minimal sedation, cognitive/memory impairment, catalepsy, and extrapyramidal symptoms.".
- Umespirone atcPrefix "none".
- Umespirone casNumber "107736-98-1".
- Umespirone fdaUniiCode "FG0A3VRL5K".
- Umespirone iupacName "3-butyl-7-[4-[4-(2-methoxyphenyl)piperazin-1-yl]butyl]-9,9-dimethyl-3,7-diazabicyclo[3.3.1]nonane-2,4,6,8-tetrone".
- Umespirone pubchem "65902".
- Umespirone thumbnail Umespirone_skeletal.svg?width=300.
- Umespirone wikiPageID "26468493".
- Umespirone wikiPageLength "4583".
- Umespirone wikiPageOutDegree "18".
- Umespirone wikiPageRevisionID "679108480".
- Umespirone wikiPageWikiLink 5-HT1A_receptor.
- Umespirone wikiPageWikiLink Affinity_(pharmacology).
- Umespirone wikiPageWikiLink Alpha-1_adrenergic_receptor.
- Umespirone wikiPageWikiLink Antipsychotic.
- Umespirone wikiPageWikiLink Anxiolytic.
- Umespirone wikiPageWikiLink Azapirone.
- Umespirone wikiPageWikiLink Catalepsy.
- Umespirone wikiPageWikiLink Category:Azapirones.
- Umespirone wikiPageWikiLink Category:Piperazines.
- Umespirone wikiPageWikiLink Cognitive_deficit.
- Umespirone wikiPageWikiLink D2_receptor.
- Umespirone wikiPageWikiLink Dopamine_receptor_D2.
- Umespirone wikiPageWikiLink Drug.
- Umespirone wikiPageWikiLink Extrapyramidal_symptom.
- Umespirone wikiPageWikiLink Extrapyramidal_symptoms.
- Umespirone wikiPageWikiLink Ligand_(biochemistry).
- Umespirone wikiPageWikiLink Partial_agonist.
- Umespirone wikiPageWikiLink Receptor_antagonist.
- Umespirone wikiPageWikiLink Sedation.
- Umespirone wikiPageWikiLink Sigma_receptor.
- Umespirone wikiPageWikiLinkText "Umespirone".
- Umespirone wikiPageWikiLinkText "umespirone".
- Umespirone atcPrefix "none".
- Umespirone c "28".
- Umespirone casNumber "107736".
- Umespirone chemspiderid "59311".
- Umespirone eliminationHalfLife "82800.0".
- Umespirone h "40".
- Umespirone hasPhotoCollection Umespirone.
- Umespirone iupacName "3".
- Umespirone legalStatus "uncontrolled".
- Umespirone molecularWeight "512.64".
- Umespirone n "4".
- Umespirone o "5".
- Umespirone pubchem "65902".
- Umespirone routesOfAdministration "oral".
- Umespirone smiles "O=C1NCCCC".
- Umespirone unii "FG0A3VRL5K".
- Umespirone wikiPageUsesTemplate Template:Adrenergics.
- Umespirone wikiPageUsesTemplate Template:Antidepressants.
- Umespirone wikiPageUsesTemplate Template:Antipsychotics.
- Umespirone wikiPageUsesTemplate Template:Anxiolytics.
- Umespirone wikiPageUsesTemplate Template:Dopaminergics.
- Umespirone wikiPageUsesTemplate Template:Drugbox.
- Umespirone wikiPageUsesTemplate Template:Nervous-system-drug-stub.
- Umespirone wikiPageUsesTemplate Template:Piperazines.
- Umespirone wikiPageUsesTemplate Template:Reflist.
- Umespirone wikiPageUsesTemplate Template:Serotonergics.
- Umespirone wikiPageUsesTemplate Template:Sigmaergics.
- Umespirone subject Category:Azapirones.
- Umespirone subject Category:Piperazines.
- Umespirone hypernym Drug.
- Umespirone type ChemicalSubstance.
- Umespirone type Drug.
- Umespirone type Antidepressant.
- Umespirone type Drug.
- Umespirone type Heterocycle.
- Umespirone type Imide.
- Umespirone type ChemicalObject.
- Umespirone type Thing.
- Umespirone type Q8386.
- Umespirone comment "Umespirone (KC-9172) is a drug of the azapirone class which possesses anxiolytic and antipsychotic properties. It behaves as a 5-HT1A receptor partial agonist (Ki = 15 nM), D2 receptor partial agonist (Ki = 23 nM), and α1-adrenoceptor receptor antagonist (Ki = 14 nM), and also has weak affinity for the sigma receptor (Ki = 558 nM). Unlike many other anxiolytics and antipsychotics, umespirone produces minimal sedation, cognitive/memory impairment, catalepsy, and extrapyramidal symptoms.".
- Umespirone label "Umespirone".
- Umespirone sameAs m.0bbtm_2.
- Umespirone sameAs Umespiron.
- Umespirone sameAs Umespiron.
- Umespirone sameAs Q7881509.
- Umespirone sameAs Q7881509.
- Umespirone wasDerivedFrom Umespirone?oldid=679108480.
- Umespirone depiction Umespirone_skeletal.svg.
- Umespirone isPrimaryTopicOf Umespirone.