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- U937_cell abstract "U937 cells are a model cell line used in biomedical research. They were isolated from the histiocytic lymphoma of a 37-year-old male patient and are used to study the behaviour and differentiation of monocytes. U937 cells mature and differentiate in response to a number of soluble stimuli, adopting the morphology and characteristics of mature macrophages.U937 cells are of the myeloid lineage and so secrete a large number of cytokines and chemokines either constitutively (e.g. IL-1 and GM-CSF) or in response to soluble stimuli. TNFα and recombinant GM-CSF independently promote IL-10 production in U937 cells. IFNγ increases the expression of chemokine receptors (CCR1, CCR3 and CCR5) as well as that of nuclear receptors for melatonin. IFNγ treatment enhances thrombin-induced IL-8 production and is required for the melatonin-induced production of IL-6.U937 can be grown in DMEM or 1640 medium plus 10% fetal bovine serum.Atromentin induces apoptosis in human leukemia U937 cells.The HLA alleles present in U937 cells are HLA-A*03:01, A*31:01, B*18:01, B*51:01, Cw*01:02 and Cw*07:02.".
- U937_cell wikiPageID "19789279".
- U937_cell wikiPageLength "3705".
- U937_cell wikiPageOutDegree "31".
- U937_cell wikiPageRevisionID "679106239".
- U937_cell wikiPageWikiLink Apoptosis.
- U937_cell wikiPageWikiLink Atromentin.
- U937_cell wikiPageWikiLink Biomedical_research.
- U937_cell wikiPageWikiLink CCR1.
- U937_cell wikiPageWikiLink CCR3_(gene).
- U937_cell wikiPageWikiLink CCR5.
- U937_cell wikiPageWikiLink Category:Cell_lines.
- U937_cell wikiPageWikiLink Cell_culture.
- U937_cell wikiPageWikiLink Cell_line.
- U937_cell wikiPageWikiLink Cellular_differentiation.
- U937_cell wikiPageWikiLink Chemokine.
- U937_cell wikiPageWikiLink Chemokine_receptor.
- U937_cell wikiPageWikiLink Chemokines.
- U937_cell wikiPageWikiLink Cytokine.
- U937_cell wikiPageWikiLink Cytokines.
- U937_cell wikiPageWikiLink DMEM.
- U937_cell wikiPageWikiLink Eagles_minimal_essential_medium.
- U937_cell wikiPageWikiLink GM-CSF.
- U937_cell wikiPageWikiLink Gene_expression.
- U937_cell wikiPageWikiLink Granulocyte_macrophage_colony-stimulating_factor.
- U937_cell wikiPageWikiLink Histiocyte.
- U937_cell wikiPageWikiLink Histiocytic.
- U937_cell wikiPageWikiLink Human_leukocyte_antigen.
- U937_cell wikiPageWikiLink Interferon-gamma.
- U937_cell wikiPageWikiLink Interferon_gamma.
- U937_cell wikiPageWikiLink Interleukin_1.
- U937_cell wikiPageWikiLink Interleukin_10.
- U937_cell wikiPageWikiLink Interleukin_1_family.
- U937_cell wikiPageWikiLink Interleukin_6.
- U937_cell wikiPageWikiLink Interleukin_8.
- U937_cell wikiPageWikiLink Leukemia.
- U937_cell wikiPageWikiLink Lymphoma.
- U937_cell wikiPageWikiLink Macrophage.
- U937_cell wikiPageWikiLink Medical_research.
- U937_cell wikiPageWikiLink Melatonin.
- U937_cell wikiPageWikiLink Monocyte.
- U937_cell wikiPageWikiLink Monocytes.
- U937_cell wikiPageWikiLink Myelocyte.
- U937_cell wikiPageWikiLink Myeloid_cell.
- U937_cell wikiPageWikiLink Nuclear_receptor.
- U937_cell wikiPageWikiLink TNF_alpha.
- U937_cell wikiPageWikiLink Thrombin.
- U937_cell wikiPageWikiLink Tumor_necrosis_factor_alpha.
- U937_cell wikiPageWikiLinkText "U-937".
- U937_cell wikiPageWikiLinkText "U937 cell".
- U937_cell hasPhotoCollection U937_cell.
- U937_cell wikiPageUsesTemplate Template:Reflist.
- U937_cell subject Category:Cell_lines.
- U937_cell hypernym Line.
- U937_cell type Line.
- U937_cell comment "U937 cells are a model cell line used in biomedical research. They were isolated from the histiocytic lymphoma of a 37-year-old male patient and are used to study the behaviour and differentiation of monocytes. U937 cells mature and differentiate in response to a number of soluble stimuli, adopting the morphology and characteristics of mature macrophages.U937 cells are of the myeloid lineage and so secrete a large number of cytokines and chemokines either constitutively (e.g.".
- U937_cell label "U937 cell".
- U937_cell sameAs m.04q28f5.
- U937_cell sameAs Q7863610.
- U937_cell sameAs Q7863610.
- U937_cell wasDerivedFrom U937_cell?oldid=679106239.
- U937_cell isPrimaryTopicOf U937_cell.