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- Type_I_topoisomerase abstract "In molecular biology Type I topoisomerases are enzymes that cut one of the two strands of double-stranded DNA, relax the strand, and reanneal the strand. They are further subdivided into two structurally and mechanistically distinct topoisomerases: type IA and type IB. Type IA topoisomerases change the linking number of a circular DNA strand by units of strictly 1. Type IB topoisomerases change the linking number by multiples of 1 (n). Historically, type IA topoisomerases are referred to as prokaryotic topo I, while type IB topoisomerases are referred to as eukaryotic topoisomerase. This distinction, however, no longer applies as type IA and type IB topoisomerases exist in all domains of life.Functionally, these subclasses perform very specialized functions. Prokaryotic topoisomerase I (topo IA) can only relax negative supercoiled DNA, whereas eukaryotic topoisomerase I (topo IB) can introduce positive supercoils, decatenate single-stranded DNA, and relax DNA.".
- Type_I_topoisomerase symbol "VirDNA-topo-I_N".
- Type_I_topoisomerase thumbnail PDB_1vcc_EBI.jpg?width=300.
- Type_I_topoisomerase wikiPageExternalLink 5.99.1.2.
- Type_I_topoisomerase wikiPageExternalLink 5.99.1.3.
- Type_I_topoisomerase wikiPageExternalLink explore.do?structureId=2csb.
- Type_I_topoisomerase wikiPageExternalLink explore.do?structureId=2csd.
- Type_I_topoisomerase wikiPageID "8996488".
- Type_I_topoisomerase wikiPageLength "12958".
- Type_I_topoisomerase wikiPageOutDegree "40".
- Type_I_topoisomerase wikiPageRevisionID "651727225".
- Type_I_topoisomerase wikiPageWikiLink Active_site.
- Type_I_topoisomerase wikiPageWikiLink Adenosine_triphosphate.
- Type_I_topoisomerase wikiPageWikiLink Anti-Scl-70_antibodies.
- Type_I_topoisomerase wikiPageWikiLink Antigen.
- Type_I_topoisomerase wikiPageWikiLink Atomic_mass_unit.
- Type_I_topoisomerase wikiPageWikiLink Autoantibodies.
- Type_I_topoisomerase wikiPageWikiLink Autoantibody.
- Type_I_topoisomerase wikiPageWikiLink Biomolecular_structure.
- Type_I_topoisomerase wikiPageWikiLink Camptothecin.
- Type_I_topoisomerase wikiPageWikiLink Category:EC_5.99.1.
- Type_I_topoisomerase wikiPageWikiLink Chromosome.
- Type_I_topoisomerase wikiPageWikiLink DNA.
- Type_I_topoisomerase wikiPageWikiLink DNA_replication.
- Type_I_topoisomerase wikiPageWikiLink DNA_supercoil.
- Type_I_topoisomerase wikiPageWikiLink Enzyme.
- Type_I_topoisomerase wikiPageWikiLink Enzymes.
- Type_I_topoisomerase wikiPageWikiLink Eukaryote.
- Type_I_topoisomerase wikiPageWikiLink Eukaryotic.
- Type_I_topoisomerase wikiPageWikiLink File:TopoI.png.
- Type_I_topoisomerase wikiPageWikiLink Genetic_recombination.
- Type_I_topoisomerase wikiPageWikiLink Irinotecan.
- Type_I_topoisomerase wikiPageWikiLink Kilodalton.
- Type_I_topoisomerase wikiPageWikiLink Linking_number.
- Type_I_topoisomerase wikiPageWikiLink Methanopyrus.
- Type_I_topoisomerase wikiPageWikiLink Methanopyrus_kandleri.
- Type_I_topoisomerase wikiPageWikiLink Mitosis.
- Type_I_topoisomerase wikiPageWikiLink Phosphodiester.
- Type_I_topoisomerase wikiPageWikiLink Phosphodiester_bond.
- Type_I_topoisomerase wikiPageWikiLink Positive_and_negative_predictive_values.
- Type_I_topoisomerase wikiPageWikiLink Positive_predictive_value.
- Type_I_topoisomerase wikiPageWikiLink Prokaryote.
- Type_I_topoisomerase wikiPageWikiLink Prokaryotic.
- Type_I_topoisomerase wikiPageWikiLink Reverse_gyrase.
- Type_I_topoisomerase wikiPageWikiLink Scissile.
- Type_I_topoisomerase wikiPageWikiLink Scleroderma.
- Type_I_topoisomerase wikiPageWikiLink Secondary_structure.
- Type_I_topoisomerase wikiPageWikiLink Supercoil.
- Type_I_topoisomerase wikiPageWikiLink Topoisomerase.
- Type_I_topoisomerase wikiPageWikiLink Topology.
- Type_I_topoisomerase wikiPageWikiLink Topotecan.
- Type_I_topoisomerase wikiPageWikiLink Transcription_(genetics).
- Type_I_topoisomerase wikiPageWikiLink Transcriptional_regulation.
- Type_I_topoisomerase wikiPageWikiLink Type_II_topoisomerase.
- Type_I_topoisomerase wikiPageWikiLink Tyrosine.
- Type_I_topoisomerase wikiPageWikiLink File:1a36_topoisomerase-IB-active-site.png.
- Type_I_topoisomerase wikiPageWikiLink File:Topoisomerase_IB_Active_Site.jpg.
- Type_I_topoisomerase wikiPageWikiLinkText "Topoisomerase".
- Type_I_topoisomerase wikiPageWikiLinkText "Type I topoisomerase".
- Type_I_topoisomerase wikiPageWikiLinkText "topoisomerase 1".
- Type_I_topoisomerase wikiPageWikiLinkText "topoisomerase I".
- Type_I_topoisomerase wikiPageWikiLinkText "type I topoisomerase".
- Type_I_topoisomerase caption "amino terminal 9kda domain of vaccinia virus dna topoisomerase i residues 1-77, experimental electron density for residues 1-77".
- Type_I_topoisomerase hasPhotoCollection Type_I_topoisomerase.
- Type_I_topoisomerase interpro "IPR015346".
- Type_I_topoisomerase name "VirDNA-topo-I_N".
- Type_I_topoisomerase pfam "PF09266".
- Type_I_topoisomerase scop "1".
- Type_I_topoisomerase symbol "VirDNA-topo-I_N".
- Type_I_topoisomerase wikiPageUsesTemplate Template:Infobox_protein_family.
- Type_I_topoisomerase wikiPageUsesTemplate Template:Main.
- Type_I_topoisomerase wikiPageUsesTemplate Template:MeshName.
- Type_I_topoisomerase wikiPageUsesTemplate Template:Reflist.
- Type_I_topoisomerase wikiPageUsesTemplate Template:Topoisomerases.
- Type_I_topoisomerase subject Category:EC_5.99.1.
- Type_I_topoisomerase hypernym Enzymes.
- Type_I_topoisomerase type Biomolecule.
- Type_I_topoisomerase type Protein.
- Type_I_topoisomerase type Chemical.
- Type_I_topoisomerase type Thing.
- Type_I_topoisomerase type Q206229.
- Type_I_topoisomerase type Q8054.
- Type_I_topoisomerase comment "In molecular biology Type I topoisomerases are enzymes that cut one of the two strands of double-stranded DNA, relax the strand, and reanneal the strand. They are further subdivided into two structurally and mechanistically distinct topoisomerases: type IA and type IB. Type IA topoisomerases change the linking number of a circular DNA strand by units of strictly 1. Type IB topoisomerases change the linking number by multiples of 1 (n).".
- Type_I_topoisomerase label "Type I topoisomerase".
- Type_I_topoisomerase sameAs m.027ssg_.
- Type_I_topoisomerase sameAs Tip_I_topoizomeraza.
- Type_I_topoisomerase sameAs Tip_I_topoizomeraza.
- Type_I_topoisomerase sameAs Q7860880.
- Type_I_topoisomerase sameAs Q7860880.
- Type_I_topoisomerase wasDerivedFrom Type_I_topoisomerase?oldid=651727225.
- Type_I_topoisomerase depiction PDB_1vcc_EBI.jpg.
- Type_I_topoisomerase isPrimaryTopicOf Type_I_topoisomerase.