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- Trisynaptic_circuit abstract "The trisynaptic circuit, or trisynaptic loop is a relay of synaptic transmission in the hippocampus. The circuit was initially described by the neuroanatomist Santiago Ramon y Cajal, in the early twentieth century, using the Golgi staining method. After the discovery of the trisynaptic circuit, a series of research has been conducted to determine the mechanisms driving this circuit. Today, research is focused on how this loop interacts with other parts of the brain, and how it influences human physiology and behaviour. For example, it has been shown that disruptions within the trisynaptic circuit leads to behavioural changes in rodent and feline models.The trisynaptic circuit is a relay of synaptic transmission in the hippocampus, which is made up of three major cell groups: granule cells, CA3 ("Cornu Ammonis" area 3) pyramidal neurons, and CA1 ("Cornu Ammonis" area 1) pyramidal cells. The hippocampal relay involves 3 main regions within the hippocampus which are classified according to their cell type and projection fibers. The first projection of the hippocampus occurs between the entorhinal cortex and the dentate gyrus. The entorhinal cortex transmits its signals from the parahippocampal gyrus to the dentate gyrus via granule cell fibers known collectively as the perforant path. The dentate gyrus then synapses on pyramidal cells in CA3 via mossy cell fibers. CA3 then fires to CA1 via Schaffer collaterals which synapse in the subiculum and are carried out through the fornix. Collectively the dentate gyrus, CA1 and CA3 of the hippocampus compose the trisynaptic loop.EC → DG via the perforant path(synapse 1), DG → CA3 via mossy fibres(synapse 2), CA3 → CA1 via schaffer collaterals(synapse 3)".
- Trisynaptic_circuit wikiPageID "16526850".
- Trisynaptic_circuit wikiPageLength "15116".
- Trisynaptic_circuit wikiPageOutDegree "43".
- Trisynaptic_circuit wikiPageRevisionID "651767684".
- Trisynaptic_circuit wikiPageWikiLink Amygdala.
- Trisynaptic_circuit wikiPageWikiLink Association_cortex.
- Trisynaptic_circuit wikiPageWikiLink Brodmann_area.
- Trisynaptic_circuit wikiPageWikiLink Brodmann_areas.
- Trisynaptic_circuit wikiPageWikiLink Category:Cell_signaling.
- Trisynaptic_circuit wikiPageWikiLink Cerebral_cortex.
- Trisynaptic_circuit wikiPageWikiLink Cingulate_cortex.
- Trisynaptic_circuit wikiPageWikiLink Crus_of_fornix.
- Trisynaptic_circuit wikiPageWikiLink Dentate_gyrus.
- Trisynaptic_circuit wikiPageWikiLink Entorhinal_cortex.
- Trisynaptic_circuit wikiPageWikiLink Fornix_(neuroanatomy).
- Trisynaptic_circuit wikiPageWikiLink Fornix_of_the_brain.
- Trisynaptic_circuit wikiPageWikiLink Golgis_method.
- Trisynaptic_circuit wikiPageWikiLink Hippocampal_sulcus.
- Trisynaptic_circuit wikiPageWikiLink Hippocampus.
- Trisynaptic_circuit wikiPageWikiLink Hippocampus_anatomy.
- Trisynaptic_circuit wikiPageWikiLink Hypercapnia.
- Trisynaptic_circuit wikiPageWikiLink Hyperoxia.
- Trisynaptic_circuit wikiPageWikiLink Hypoxia_(medical).
- Trisynaptic_circuit wikiPageWikiLink Mammillary_bodies.
- Trisynaptic_circuit wikiPageWikiLink Mammillary_body.
- Trisynaptic_circuit wikiPageWikiLink Mammillothalamic_fasciculus.
- Trisynaptic_circuit wikiPageWikiLink Medial_septal_nucleus.
- Trisynaptic_circuit wikiPageWikiLink Medial_septum.
- Trisynaptic_circuit wikiPageWikiLink Medial_temporal_lobe.
- Trisynaptic_circuit wikiPageWikiLink Morris_water_maze.
- Trisynaptic_circuit wikiPageWikiLink Morris_water_navigation_task.
- Trisynaptic_circuit wikiPageWikiLink Mossy_fiber.
- Trisynaptic_circuit wikiPageWikiLink Mossy_fibres.
- Trisynaptic_circuit wikiPageWikiLink Neurogenesis.
- Trisynaptic_circuit wikiPageWikiLink Neurotransmission.
- Trisynaptic_circuit wikiPageWikiLink Papez_circuit.
- Trisynaptic_circuit wikiPageWikiLink Perforant_path.
- Trisynaptic_circuit wikiPageWikiLink Perforant_pathway.
- Trisynaptic_circuit wikiPageWikiLink Rapid_eye_movement_sleep.
- Trisynaptic_circuit wikiPageWikiLink Region_III_of_hippocampus_proper.
- Trisynaptic_circuit wikiPageWikiLink Region_I_of_hippocampus_proper.
- Trisynaptic_circuit wikiPageWikiLink Santiago_Ramón_y_Cajal.
- Trisynaptic_circuit wikiPageWikiLink Schaffer_collateral.
- Trisynaptic_circuit wikiPageWikiLink Subiculum.
- Trisynaptic_circuit wikiPageWikiLink Synaptic_transmission.
- Trisynaptic_circuit wikiPageWikiLink Temporal_lobe.
- Trisynaptic_circuit wikiPageWikiLink Thalamus.
- Trisynaptic_circuit wikiPageWikiLink Theta_rhythm.
- Trisynaptic_circuit wikiPageWikiLink Theta_waves.
- Trisynaptic_circuit wikiPageWikiLinkText "Trisynaptic circuit".
- Trisynaptic_circuit hasPhotoCollection Trisynaptic_circuit.
- Trisynaptic_circuit wikiPageUsesTemplate Template:Reflist.
- Trisynaptic_circuit subject Category:Cell_signaling.
- Trisynaptic_circuit hypernym Relay.
- Trisynaptic_circuit type ArtificialSatellite.
- Trisynaptic_circuit comment "The trisynaptic circuit, or trisynaptic loop is a relay of synaptic transmission in the hippocampus. The circuit was initially described by the neuroanatomist Santiago Ramon y Cajal, in the early twentieth century, using the Golgi staining method. After the discovery of the trisynaptic circuit, a series of research has been conducted to determine the mechanisms driving this circuit.".
- Trisynaptic_circuit label "Trisynaptic circuit".
- Trisynaptic_circuit sameAs m.03y98pl.
- Trisynaptic_circuit sameAs Q7844249.
- Trisynaptic_circuit sameAs Q7844249.
- Trisynaptic_circuit wasDerivedFrom Trisynaptic_circuit?oldid=651767684.
- Trisynaptic_circuit isPrimaryTopicOf Trisynaptic_circuit.