Matches in DBpedia 2015-10 for { <http://dbpedia.org/resource/Treacle_protein> ?p ?o }
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- Treacle_protein abstract "Treacle protein is a protein that in humans is encoded by the TCOF1 gene.This gene encodes a nucleolar protein with an LIS1 homology domain. The protein is involved in ribosomal DNA gene transcription through its interaction with upstream binding factor (UBF). Mutations in this gene have been associated with Treacher Collins syndrome, a disorder which includes abnormal craniofacial development. Alternate transcriptional splice variants encoding different isoforms have been found for this gene, but only three of them have been characterized to date.TCOF1 is a gene that provides instructions for making a protein called treacle. This protein is active during early embryonic development in structures that become bones and other tissues in the face. Although the precise function of this protein is unknown, researchers believe that it plays a critical role in the development of facial bones and related structures.Studies suggest that treacle is involved in the production of a molecule called ribosomal RNA (rRNA) within cells. Treacle is active in the nucleolus, which is a small region inside the nucleus where rRNA is produced. As a major component of cell structures called ribosomes, rRNA is essential for the assembly of proteins.Aside from its interaction with UBF, treacle has been implicated in the methylation of the precursor to mature ribosomal RNA by interaction with the nucleolar protein pNop56.The TCOF1 gene is located on the long (q) arm of chromosome 5 between positions 32 and 33.1, from base pair 149,717,427 to base pair 149,760,047.".
- Treacle_protein entrezgene "6949".
- Treacle_protein wikiPageExternalLink carddisp?TCOF1.
- Treacle_protein wikiPageExternalLink br.fcgi?book=gene&part=tcs.
- Treacle_protein wikiPageID "3429930".
- Treacle_protein wikiPageLength "11356".
- Treacle_protein wikiPageOutDegree "19".
- Treacle_protein wikiPageRevisionID "679103908".
- Treacle_protein wikiPageWikiLink Base_pair.
- Treacle_protein wikiPageWikiLink Bone.
- Treacle_protein wikiPageWikiLink Category:Human_genes.
- Treacle_protein wikiPageWikiLink Cell_nucleus.
- Treacle_protein wikiPageWikiLink Chromosome_5_(human).
- Treacle_protein wikiPageWikiLink Cleft_lip_and_palate.
- Treacle_protein wikiPageWikiLink Cleft_palate.
- Treacle_protein wikiPageWikiLink DNA.
- Treacle_protein wikiPageWikiLink Embryo.
- Treacle_protein wikiPageWikiLink Gene.
- Treacle_protein wikiPageWikiLink Methylation.
- Treacle_protein wikiPageWikiLink Mutation.
- Treacle_protein wikiPageWikiLink Nucleolus.
- Treacle_protein wikiPageWikiLink Protein.
- Treacle_protein wikiPageWikiLink Ribosomal_RNA.
- Treacle_protein wikiPageWikiLink Ribosome.
- Treacle_protein wikiPageWikiLink Treacher-Collins_syndrome.
- Treacle_protein wikiPageWikiLink Treacher_Collins_syndrome.
- Treacle_protein wikiPageWikiLinkText "Treacle protein".
- Treacle_protein wikiPageWikiLinkText "treacle".
- Treacle_protein hasPhotoCollection Treacle_protein.
- Treacle_protein requireManualInspection "no".
- Treacle_protein summaryText "This gene encodes a nucleolar protein with an LIS1 homology domain. The protein is involved in ribosomal DNA gene transcription through its interaction with upstream binding factor . Mutations in this gene have been associated with Treacher Collins syndrome, a disorder which includes abnormal craniofacial development. Alternate transcriptional splice variants encoding different isoforms have been found for this gene, but only three of them have been characterized to date.".
- Treacle_protein updateCitations "yes".
- Treacle_protein updatePage "yes".
- Treacle_protein updateProteinBox "yes".
- Treacle_protein updateSummary "yes".
- Treacle_protein wikiPageUsesTemplate Template:MeshName.
- Treacle_protein wikiPageUsesTemplate Template:Nucleus.
- Treacle_protein wikiPageUsesTemplate Template:PBB.
- Treacle_protein wikiPageUsesTemplate Template:PBB_Controls.
- Treacle_protein wikiPageUsesTemplate Template:PBB_Further_reading.
- Treacle_protein wikiPageUsesTemplate Template:PBB_Summary.
- Treacle_protein wikiPageUsesTemplate Template:Refbegin.
- Treacle_protein wikiPageUsesTemplate Template:Refend.
- Treacle_protein wikiPageUsesTemplate Template:Reflist.
- Treacle_protein wikiPageUsesTemplate Template:UCSC_gene_details.
- Treacle_protein wikiPageUsesTemplate Template:UCSC_genome_browser.
- Treacle_protein subject Category:Human_genes.
- Treacle_protein hypernym Protein.
- Treacle_protein type Biomolecule.
- Treacle_protein type Protein.
- Treacle_protein type Thing.
- Treacle_protein type Q206229.
- Treacle_protein type Q8054.
- Treacle_protein comment "Treacle protein is a protein that in humans is encoded by the TCOF1 gene.This gene encodes a nucleolar protein with an LIS1 homology domain. The protein is involved in ribosomal DNA gene transcription through its interaction with upstream binding factor (UBF). Mutations in this gene have been associated with Treacher Collins syndrome, a disorder which includes abnormal craniofacial development.".
- Treacle_protein label "Treacle protein".
- Treacle_protein sameAs m.09c0h5.
- Treacle_protein sameAs Q7836550.
- Treacle_protein sameAs Q7836550.
- Treacle_protein wasDerivedFrom Treacle_protein?oldid=679103908.
- Treacle_protein isPrimaryTopicOf Treacle_protein.