Matches in DBpedia 2015-10 for { <http://dbpedia.org/resource/Transaminase> ?p ?o }
- Transaminase abstract "In biochemistry, a transaminase or an aminotransferase is an enzyme that catalyzes a type of reaction between an amino acid and an α-keto acid. They are important in the synthesis of amino acids, which form proteins. In medicine, they are an important indicator of liver damage. An amino acid contains an amine (NH2) group. A keto acid contains a keto (=O) group. In transamination, the NH2 group on one molecule is exchanged with the =O group on the other molecule. The amino acid becomes a keto acid, and the keto acid becomes an amino acid.Some transamination activities of the ribosome have been found to be catalyzed by so-called ribozymes (RNA enzymes). Examples being the hammerhead ribozyme, the VS ribozyme and the hairpin ribozyme.The transaminase enzymes are important in the production of various amino acids, and measuring the concentrations of various transaminases in the blood is important in the diagnosing and tracking many diseases. Transaminases require the coenzyme pyridoxal-phosphate, which is converted into pyridoxamine in the first phase of the reaction, when an amino acid is converted into a keto acid. Enzyme-bound pyridoxamine in turn reacts with pyruvate, oxaloacetate, or alpha-ketoglutarate, giving alanine, aspartic acid, or glutamic acid, respectively. Many transamination reactions occur in tissues, catalysed by transaminases specific for a particular amino/keto acid pair. The reactions are readily reversible, the direction being determined by which of the reactants are in excess. The specific enzymes are named from one of the reactant pairs, for example; the reaction between glutamic acid and pyruvic acid to make alpha ketoglutaric acid and alanine is called glutamic-pyruvic transaminase or GPT for short.Tissue transaminase activities can be investigated by incubating a homogenate with various amino/keto acid pairs. Transamination is demonstrated if the corresponding new amino acid and keto acid are formed, as revealed by paper chromatography. Reversibility is demonstrated by using the complementary keto/amino acid pair as starting reactants. After chromatogram has been taken out of the solvent the chromatogram is then treated with ninhydrin to locate the spots.The presence of elevated transaminases can be an indicator of liver damage. Two important transaminase enzymes are aspartate transaminase (AST), also known as serum glutamic oxaloacetic transaminase (SGOT); and alanine transaminase (ALT), also called alanine aminotransferase (ALAT) or serum glutamate-pyruvate transaminase (SGPT). This discovery was made by Fernando De Ritis, Mario Coltorti and Giuseppe Giusti in 1955 at the University of Naples.".
- Transaminase thumbnail Transaminierung.svg?width=300.
- Transaminase wikiPageID "2166084".
- Transaminase wikiPageLength "5081".
- Transaminase wikiPageOutDegree "51".
- Transaminase wikiPageRevisionID "676000206".
- Transaminase wikiPageWikiLink 4-Aminobutyrate_aminotransferase.
- Transaminase wikiPageWikiLink 4-aminobutyrate_transaminase.
- Transaminase wikiPageWikiLink Alanine.
- Transaminase wikiPageWikiLink Alanine_cycle.
- Transaminase wikiPageWikiLink Alanine_transaminase.
- Transaminase wikiPageWikiLink Alpha-Ketoglutaric_acid.
- Transaminase wikiPageWikiLink Alpha-keto_acid.
- Transaminase wikiPageWikiLink Alpha-ketoglutarate.
- Transaminase wikiPageWikiLink Amine.
- Transaminase wikiPageWikiLink Amino_acid.
- Transaminase wikiPageWikiLink Anaerobic_metabolism.
- Transaminase wikiPageWikiLink Aspartate.
- Transaminase wikiPageWikiLink Aspartate_transaminase.
- Transaminase wikiPageWikiLink Aspartic_acid.
- Transaminase wikiPageWikiLink Biochemistry.
- Transaminase wikiPageWikiLink Blood_sugar.
- Transaminase wikiPageWikiLink Cahill_cycle.
- Transaminase wikiPageWikiLink Catalysis.
- Transaminase wikiPageWikiLink Catalyze.
- Transaminase wikiPageWikiLink Category:EC_2.6.1.
- Transaminase wikiPageWikiLink Category:Hepatology.
- Transaminase wikiPageWikiLink Category:Transferases.
- Transaminase wikiPageWikiLink Concentration.
- Transaminase wikiPageWikiLink Cori_cycle.
- Transaminase wikiPageWikiLink Disease.
- Transaminase wikiPageWikiLink Elevated_transaminases.
- Transaminase wikiPageWikiLink Enzyme.
- Transaminase wikiPageWikiLink Fermentation.
- Transaminase wikiPageWikiLink Gluconeogenesis.
- Transaminase wikiPageWikiLink Glutamate.
- Transaminase wikiPageWikiLink Glutamic_acid.
- Transaminase wikiPageWikiLink Hairpin_ribozyme.
- Transaminase wikiPageWikiLink Hammerhead_ribozyme.
- Transaminase wikiPageWikiLink Keto_acid.
- Transaminase wikiPageWikiLink Ketone.
- Transaminase wikiPageWikiLink Liver.
- Transaminase wikiPageWikiLink Ninhydrin.
- Transaminase wikiPageWikiLink Oxaloacetate.
- Transaminase wikiPageWikiLink Oxaloacetic_acid.
- Transaminase wikiPageWikiLink Protein.
- Transaminase wikiPageWikiLink Proteins.
- Transaminase wikiPageWikiLink Pyridoxal-phosphate.
- Transaminase wikiPageWikiLink Pyridoxal_phosphate.
- Transaminase wikiPageWikiLink Pyridoxamine.
- Transaminase wikiPageWikiLink Pyruvate.
- Transaminase wikiPageWikiLink Pyruvic_acid.
- Transaminase wikiPageWikiLink Ribosome.
- Transaminase wikiPageWikiLink Ribozyme.
- Transaminase wikiPageWikiLink Ribozymes.
- Transaminase wikiPageWikiLink Transamination.
- Transaminase wikiPageWikiLink University_of_Naples.
- Transaminase wikiPageWikiLink University_of_Naples_Federico_II.
- Transaminase wikiPageWikiLink VS_ribozyme.
- Transaminase wikiPageWikiLink Valproate.
- Transaminase wikiPageWikiLink Valproic_acid.
- Transaminase wikiPageWikiLink Wiktionary:homogenate.
- Transaminase wikiPageWikiLink File:Aspartate_transaminase.png.
- Transaminase wikiPageWikiLink File:Transaminierung.svg.
- Transaminase wikiPageWikiLinkText "Transaminase".
- Transaminase wikiPageWikiLinkText "aminotransferase".
- Transaminase wikiPageWikiLinkText "transaminase".
- Transaminase wikiPageWikiLinkText "transaminases".
- Transaminase wikiPageWikiLinkText "transaminated".
- Transaminase wikiPageWikiLinkText "ω-transaminase".
- Transaminase hasPhotoCollection Transaminase.
- Transaminase wikiPageUsesTemplate Template:Enzymes.
- Transaminase wikiPageUsesTemplate Template:MeshName.
- Transaminase wikiPageUsesTemplate Template:Reflist.
- Transaminase wikiPageUsesTemplate Template:Transaminases.
- Transaminase subject Category:EC_2.6.1.
- Transaminase subject Category:Hepatology.
- Transaminase subject Category:Transferases.
- Transaminase hypernym Enzyme.
- Transaminase type Protein.
- Transaminase type Specialty.
- Transaminase comment "In biochemistry, a transaminase or an aminotransferase is an enzyme that catalyzes a type of reaction between an amino acid and an α-keto acid. They are important in the synthesis of amino acids, which form proteins. In medicine, they are an important indicator of liver damage. An amino acid contains an amine (NH2) group. A keto acid contains a keto (=O) group. In transamination, the NH2 group on one molecule is exchanged with the =O group on the other molecule.".
- Transaminase label "Transaminase".
- Transaminase sameAs Aminotransferasa.
- Transaminase sameAs Aminotransferasen.
- Transaminase sameAs Aminotransferasa.
- Transaminase sameAs Transaminasa.
- Transaminase sameAs ترانسآمیناز.
- Transaminase sameAs Transaminaasit.
- Transaminase sameAs Transaminase.
- Transaminase sameAs Transaminaze.
- Transaminase sameAs Transaminasi.
- Transaminase sameAs アミノ基転移酵素.
- Transaminase sameAs Трансаминаза.
- Transaminase sameAs Aminotransferazy.
- Transaminase sameAs Transaminase.
- Transaminase sameAs m.06rrs3.
- Transaminase sameAs Аминотрансферазы.
- Transaminase sameAs Transaminaser.
- Transaminase sameAs Q424288.