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Matches in DBpedia 2015-10 for { <http://dbpedia.org/resource/Toxicodynamics> ?p ?o }

• Toxicodynamics abstract "Toxicodynamics, termed pharmacodynamics in pharmacology, describes the dynamic interactions of a toxicant with a biological target and its biological effects. A biological target, also known as the site of action, can be binding proteins, ion channels, DNA, or a variety of other receptors. When a toxicant enters an organism, it can interact with these receptors and produce structural or functional alterations. The mechanism of action of the toxicant, as determined by a toxicant’s chemical properties, will determine what receptors are targeted and the overall toxic effect at the cellular level and organismal level.Toxicants have been grouped together according to their chemical properties by way of quantitative structure-activity relationships (QSARs), which allows prediction of toxic action based on these properties. endocrine disrupting chemicals (EDCs) and carcinogens are examples of classes of toxicants that can act as QSARs. EDCs mimic or block transcriptional activation normally caused by natural steroid hormones. These types of chemicals can act on androgen receptors, estrogen receptors and thyroid hormone receptors. This mechanism can include such toxicants as dichlorodiphenyltrichloroethane (DDE) and polychlorinated biphenyls (PCBs). Another class of chemicals, carcinogens, are substances that cause cancer and can be classified as genotoxic or nongenotoxic carcinogens. These categories include toxicants such as polycyclic aromatic hydrocarbon (PAHs) and carbon tetrachloride (CCl4). The process of toxicodynamics can be useful for application in environmental risk assessment by implementing toxicokinetic-toxicodynamic (TKTD) models. TKTD models include phenomenas such as time-varying exposure, carry-over toxicity, organism recovery time, effects of mixtures, and extrapolation to untested chemicals and species. Due to their advantages, these types of models may be more applicable for risk assessment than traditional modeling approaches.".
• Toxicodynamics thumbnail Diagram_showing_the_conceptual_pathway_of_toxicokinetics_and_toxicodynamics.png?width=300.
• Toxicodynamics wikiPageExternalLink CarbonTetrachloride.pdf.
• Toxicodynamics wikiPageExternalLink dna-damage-caused-by-polycyclic-aromatic-hydrocarbons-mechanisms-and-markers.
• Toxicodynamics wikiPageID "39515585".
• Toxicodynamics wikiPageLength "24738".
• Toxicodynamics wikiPageOutDegree "130".
• Toxicodynamics wikiPageRevisionID "648584824".
• Toxicodynamics wikiPageWikiLink Adenine.
• Toxicodynamics wikiPageWikiLink Agent-based_model.
• Toxicodynamics wikiPageWikiLink Androgen_receptor.
• Toxicodynamics wikiPageWikiLink Animal_testing.
• Toxicodynamics wikiPageWikiLink Anthropogenic.
• Toxicodynamics wikiPageWikiLink Antiandrogen.
• Toxicodynamics wikiPageWikiLink Apoptosis.
• Toxicodynamics wikiPageWikiLink Base_pair.
• Toxicodynamics wikiPageWikiLink Benign_tumor.
• Toxicodynamics wikiPageWikiLink Benz(a)anthracene.
• Toxicodynamics wikiPageWikiLink Benzo(a)pyrene.
• Toxicodynamics wikiPageWikiLink Binding_site.
• Toxicodynamics wikiPageWikiLink Bioaccumulation.
• Toxicodynamics wikiPageWikiLink Bioavailability.
• Toxicodynamics wikiPageWikiLink Biological_target.
• Toxicodynamics wikiPageWikiLink Biomarker.
• Toxicodynamics wikiPageWikiLink Biotransformation.
• Toxicodynamics wikiPageWikiLink Blood_plasma.
• Toxicodynamics wikiPageWikiLink CYP2E1.
• Toxicodynamics wikiPageWikiLink California_sea_lion.
• Toxicodynamics wikiPageWikiLink Cancer.
• Toxicodynamics wikiPageWikiLink Carbon_tetrachloride.
• Toxicodynamics wikiPageWikiLink Carcinogen.
• Toxicodynamics wikiPageWikiLink Carcinogenesis.
• Toxicodynamics wikiPageWikiLink Category:Articles_created_via_the_Article_Wizard.
• Toxicodynamics wikiPageWikiLink Category:Environment.
• Toxicodynamics wikiPageWikiLink Category:Pharmacodynamics.
• Toxicodynamics wikiPageWikiLink Category:Pollution.
• Toxicodynamics wikiPageWikiLink Category:Toxicology.
• Toxicodynamics wikiPageWikiLink Cell_membrane.
• Toxicodynamics wikiPageWikiLink Cell_nucleus.
• Toxicodynamics wikiPageWikiLink Cervix.
• Toxicodynamics wikiPageWikiLink Chemical_compound.
• Toxicodynamics wikiPageWikiLink Chemical_exposure.
• Toxicodynamics wikiPageWikiLink Chromatin.
• Toxicodynamics wikiPageWikiLink Clinical_endpoint.
• Toxicodynamics wikiPageWikiLink Concentration.
• Toxicodynamics wikiPageWikiLink Covalent_bond.
• Toxicodynamics wikiPageWikiLink Critical_Body_Residue.
• Toxicodynamics wikiPageWikiLink Cytoplasm.
• Toxicodynamics wikiPageWikiLink Cytotoxicity.
• Toxicodynamics wikiPageWikiLink DDT.
• Toxicodynamics wikiPageWikiLink DEBtox.
• Toxicodynamics wikiPageWikiLink DNA.
• Toxicodynamics wikiPageWikiLink DNA_adduct.
• Toxicodynamics wikiPageWikiLink Degradative_enzyme.
• Toxicodynamics wikiPageWikiLink Dichlorodiphenyltrichloroethane.
• Toxicodynamics wikiPageWikiLink Disease.
• Toxicodynamics wikiPageWikiLink Dose-response_relationship.
• Toxicodynamics wikiPageWikiLink Dose–response_relationship.
• Toxicodynamics wikiPageWikiLink Drug_tolerance.
• Toxicodynamics wikiPageWikiLink Ecology.
• Toxicodynamics wikiPageWikiLink Endocrine_disruptor.
• Toxicodynamics wikiPageWikiLink Endocrine_disruptors.
• Toxicodynamics wikiPageWikiLink Endocrine_system.
• Toxicodynamics wikiPageWikiLink Enzyme.
• Toxicodynamics wikiPageWikiLink Epididymitis.
• Toxicodynamics wikiPageWikiLink Epigenetics.
• Toxicodynamics wikiPageWikiLink Epithelium.
• Toxicodynamics wikiPageWikiLink Estrogen_receptor.
• Toxicodynamics wikiPageWikiLink Fallopian_tube.
• Toxicodynamics wikiPageWikiLink Fatty_acid.
• Toxicodynamics wikiPageWikiLink File:Diagram_showing_the_conceptual_pathway_of_toxicokinetics_and_toxicodynamics.png.
• Toxicodynamics wikiPageWikiLink Genotoxic.
• Toxicodynamics wikiPageWikiLink Genotoxicity.
• Toxicodynamics wikiPageWikiLink Grey_seal.
• Toxicodynamics wikiPageWikiLink Guanine.
• Toxicodynamics wikiPageWikiLink Harbor_seal.
• Toxicodynamics wikiPageWikiLink Heat_shock_protein.
• Toxicodynamics wikiPageWikiLink Hepatocarcinogen.
• Toxicodynamics wikiPageWikiLink Hepatocellular_carcinoma.
• Toxicodynamics wikiPageWikiLink Hepatotoxicity.
• Toxicodynamics wikiPageWikiLink Homeostasis.
• Toxicodynamics wikiPageWikiLink Human_impact_on_the_environment.
• Toxicodynamics wikiPageWikiLink Hypothesis.
• Toxicodynamics wikiPageWikiLink Immune_system.
• Toxicodynamics wikiPageWikiLink Ion_channel.
• Toxicodynamics wikiPageWikiLink Lake_Apopka.
• Toxicodynamics wikiPageWikiLink Lesion.
• Toxicodynamics wikiPageWikiLink Lipid_peroxidation.
• Toxicodynamics wikiPageWikiLink Lipophilicity.
• Toxicodynamics wikiPageWikiLink Liver.
• Toxicodynamics wikiPageWikiLink Malignancy.
• Toxicodynamics wikiPageWikiLink Mammary_gland.
• Toxicodynamics wikiPageWikiLink Mechanism_of_action.
• Toxicodynamics wikiPageWikiLink Metabolism.
• Toxicodynamics wikiPageWikiLink Metabolite.
• Toxicodynamics wikiPageWikiLink Mode_of_action.
• Toxicodynamics wikiPageWikiLink Neoplasm.
• Toxicodynamics wikiPageWikiLink Organ_(anatomy).
• Toxicodynamics wikiPageWikiLink Our_Stolen_Future.
• Toxicodynamics wikiPageWikiLink Oxidative_stress.

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