Matches in DBpedia 2015-10 for { <http://dbpedia.org/resource/Tianeptine> ?p ?o }
- Tianeptine abstract "Tianeptine (brand names Stablon, Coaxil, Tatinol, Tianeurax and Salymbra) is a drug used primarily in the treatment of major depressive disorder, although it may also be used to treat asthma or irritable bowel syndrome. Chemically it is a tricyclic antidepressant (TCA), but it has different pharmacological properties than typical TCAs as recent research suggests that tianeptine produces its antidepressant effects through indirect alteration of glutamate receptor activity (i.e., AMPA receptors and NMDA receptors) and release of BDNF, in turn affecting neural plasticity.Tianeptine has antidepressant and anxiolytic (anti-anxiety) properties with a relative lack of sedative, anticholinergic and cardiovascular adverse effects, thus suggesting it is particularly suitable for use in the elderly and in those following alcohol withdrawal; such persons can be more sensitive to the adverse effects of psychotropic drugs. Recent results indicate possible anticonvulsant (anti-seizure) and analgesic (painkilling) activity of tianeptine via immediate or downstream modulation of adenosine A1 receptors (as the effects could be experimentally blocked by antagonists of this receptor).Tianeptine is a full agonist at the μ-opioid and δ-opioid receptors with negligible effect at the κ-opioid receptors. Selective μ-opioid agonists typically induce euphoria, which may contribute to tianeptine's antidepressant effect.Tianeptine was discovered and patented by The French Society of Medical Research in the 1960s. Currently, tianeptine is approved in France and manufactured and marketed by Laboratories Servier SA; it is also marketed in a number of other European countries under the trade name “Coaxil” as well as in Asia (including Singapore) and Latin America as “Stablon” and “Tatinol” but it is not available in Australia, Canada, New Zealand, the U.K. or the U.S..".
- Tianeptine atcPrefix "N06".
- Tianeptine atcSuffix "AX14".
- Tianeptine bioavailability "99.0".
- Tianeptine casNumber "66981-73-5".
- Tianeptine fdaUniiCode "0T493YFU8O".
- Tianeptine iupacName "(RS)-7-(3-chloro-6-methyl-6,11-dihydrodibenzo[c,f][1,2]thiazepin-11-ylamino)heptanoic acid S,S-dioxide".
- Tianeptine pubchem "68870".
- Tianeptine thumbnail Tianeptine2DACS.svg?width=300.
- Tianeptine wikiPageExternalLink www.tianeptine.com.
- Tianeptine wikiPageID "2475030".
- Tianeptine wikiPageLength "30197".
- Tianeptine wikiPageOutDegree "155".
- Tianeptine wikiPageRevisionID "677926663".
- Tianeptine wikiPageWikiLink AMPA_receptor.
- Tianeptine wikiPageWikiLink Abdominal_pain.
- Tianeptine wikiPageWikiLink Adenosine.
- Tianeptine wikiPageWikiLink Adenosine_A1_receptor.
- Tianeptine wikiPageWikiLink Agence_française_de_sécurité_sanitaire_des_produits_de_santé.
- Tianeptine wikiPageWikiLink Agonist.
- Tianeptine wikiPageWikiLink Alcohol_withdrawal.
- Tianeptine wikiPageWikiLink Alcohol_withdrawal_syndrome.
- Tianeptine wikiPageWikiLink Amineptine.
- Tianeptine wikiPageWikiLink Amitriptyline.
- Tianeptine wikiPageWikiLink Analgesic.
- Tianeptine wikiPageWikiLink Anticholinergic.
- Tianeptine wikiPageWikiLink Anticonvulsant.
- Tianeptine wikiPageWikiLink Anxiolytic.
- Tianeptine wikiPageWikiLink Argentina.
- Tianeptine wikiPageWikiLink Asthma.
- Tianeptine wikiPageWikiLink Attention-deficit_hyperactivity_disorder.
- Tianeptine wikiPageWikiLink Attention_deficit_hyperactivity_disorder.
- Tianeptine wikiPageWikiLink Australia.
- Tianeptine wikiPageWikiLink Austria.
- Tianeptine wikiPageWikiLink BDNF.
- Tianeptine wikiPageWikiLink Bahrain.
- Tianeptine wikiPageWikiLink Barbiturate.
- Tianeptine wikiPageWikiLink Barbiturates.
- Tianeptine wikiPageWikiLink Benzodiazepine.
- Tianeptine wikiPageWikiLink Benzodiazepines.
- Tianeptine wikiPageWikiLink Bitter_taste.
- Tianeptine wikiPageWikiLink Blood_plasma.
- Tianeptine wikiPageWikiLink Brain-derived_neurotrophic_factor.
- Tianeptine wikiPageWikiLink Brazil.
- Tianeptine wikiPageWikiLink Bupropion.
- Tianeptine wikiPageWikiLink Canada.
- Tianeptine wikiPageWikiLink Capillary.
- Tianeptine wikiPageWikiLink Caracas.
- Tianeptine wikiPageWikiLink Carbogen.
- Tianeptine wikiPageWikiLink Carbon_dioxide.
- Tianeptine wikiPageWikiLink Cardiovascular.
- Tianeptine wikiPageWikiLink Category:Chloroarenes.
- Tianeptine wikiPageWikiLink Category:Dibenzothiazepines.
- Tianeptine wikiPageWikiLink Category:Drugs_with_unknown_mechanisms_of_action.
- Tianeptine wikiPageWikiLink Category:Euphoriants.
- Tianeptine wikiPageWikiLink Category:Laboratoires_Servier.
- Tianeptine wikiPageWikiLink Category:Tricyclic_antidepressants.
- Tianeptine wikiPageWikiLink Central_University_of_Venezuela.
- Tianeptine wikiPageWikiLink Central_nervous_system.
- Tianeptine wikiPageWikiLink China.
- Tianeptine wikiPageWikiLink Circulatory_system.
- Tianeptine wikiPageWikiLink Czech_Republic.
- Tianeptine wikiPageWikiLink Delta_opioid_receptor.
- Tianeptine wikiPageWikiLink Dopamine.
- Tianeptine wikiPageWikiLink Dopamine_D1_receptor.
- Tianeptine wikiPageWikiLink Dopamine_D2_receptor.
- Tianeptine wikiPageWikiLink Dopamine_D3_receptor.
- Tianeptine wikiPageWikiLink Dopamine_D4_receptor.
- Tianeptine wikiPageWikiLink Dopamine_D5_receptor.
- Tianeptine wikiPageWikiLink Dopamine_receptor.
- Tianeptine wikiPageWikiLink Dopamine_receptor_D1.
- Tianeptine wikiPageWikiLink Dopamine_receptor_D2.
- Tianeptine wikiPageWikiLink Dopamine_receptor_D3.
- Tianeptine wikiPageWikiLink Dopamine_receptor_D4.
- Tianeptine wikiPageWikiLink Dopamine_receptor_D5.
- Tianeptine wikiPageWikiLink Dopamine_reuptake_inhibitor.
- Tianeptine wikiPageWikiLink Dopamine_transporter.
- Tianeptine wikiPageWikiLink Drug_withdrawal.
- Tianeptine wikiPageWikiLink Enantiomer.
- Tianeptine wikiPageWikiLink Erectile_dysfunction.
- Tianeptine wikiPageWikiLink Euphoria.
- Tianeptine wikiPageWikiLink Faeces.
- Tianeptine wikiPageWikiLink Feces.
- Tianeptine wikiPageWikiLink Fibromyalgia.
- Tianeptine wikiPageWikiLink File:StablonBox.jpg.
- Tianeptine wikiPageWikiLink Fluoxetine.
- Tianeptine wikiPageWikiLink France.
- Tianeptine wikiPageWikiLink French_Health_Products_Safety_Agency.
- Tianeptine wikiPageWikiLink Gastralgia.
- Tianeptine wikiPageWikiLink Germany.
- Tianeptine wikiPageWikiLink Glutamate.
- Tianeptine wikiPageWikiLink Glutamic_acid.
- Tianeptine wikiPageWikiLink Hepatic.
- Tianeptine wikiPageWikiLink Hepatitis.
- Tianeptine wikiPageWikiLink Hippocampus_anatomy.
- Tianeptine wikiPageWikiLink Hot_flash.
- Tianeptine wikiPageWikiLink Hot_flushes.
- Tianeptine wikiPageWikiLink Hungary.
- Tianeptine wikiPageWikiLink Hyperthermia.
- Tianeptine wikiPageWikiLink Hypomania.