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- Thiolutin abstract "Thiolutin is a sulfur-containing antibiotic, which is a potent inhibitor of bacterial and yeast RNA polymerases. It was found to inhibit in vitro RNA synthesis directed by all three yeast RNA polymerases (I, II, and III). Thiolutin is also an inhibitor of mannan and glucan formation in Saccharomyces cerevisiae and used for the analysis of mRNA stability. Studies have shown that thiolutin inhibits adhesion of human umbilical vein endothelial cells (HUVECs) to vitronectin and thus suppresses tumor cell-induced angiogenesis in vivo.Thiolutin is formed in submerged fermentation by several strains of Streptomycetes luteosporeus. Some sources erroneously specify "aureothricin" as a synonym of thiolutin. Aureothricin is an antibiotic very similar to thiolutin, and is created as a by-product during the thiolutin fermentation.".
- Thiolutin atcPrefix "none".
- Thiolutin casNumber "87-11-6".
- Thiolutin iupacName "N-(4-methyl-5-oxo-4,5-dihydro[1,2]dithiolo[4,3-b]pyrrol-6-yl)acetamide".
- Thiolutin pubchem "6870".
- Thiolutin thumbnail Thiolutin.png?width=300.
- Thiolutin wikiPageID "12083623".
- Thiolutin wikiPageLength "3453".
- Thiolutin wikiPageOutDegree "11".
- Thiolutin wikiPageRevisionID "651358908".
- Thiolutin wikiPageWikiLink Category:Acetamides.
- Thiolutin wikiPageWikiLink Category:Antibiotics.
- Thiolutin wikiPageWikiLink Category:Lactams.
- Thiolutin wikiPageWikiLink Category:Organic_disulfides.
- Thiolutin wikiPageWikiLink Glucan.
- Thiolutin wikiPageWikiLink Human_umbilical_vein_endothelial_cell.
- Thiolutin wikiPageWikiLink Industrial_fermentation.
- Thiolutin wikiPageWikiLink Mannan.
- Thiolutin wikiPageWikiLink Saccharomyces_cerevisiae.
- Thiolutin wikiPageWikiLink Streptomyces.
- Thiolutin wikiPageWikiLink Vitronectin.
- Thiolutin wikiPageWikiLinkText "Thiolutin".
- Thiolutin alt "Skeletal formula of thiolutin".
- Thiolutin alt "Space-filling model of the thiolutin molecule".
- Thiolutin atcPrefix "none".
- Thiolutin c "8".
- Thiolutin casNumber "87".
- Thiolutin chembl "507026".
- Thiolutin chemspiderid "6608".
- Thiolutin h "8".
- Thiolutin hasPhotoCollection Thiolutin.
- Thiolutin image "Thiolutin 3D spacefill.png".
- Thiolutin inchi "1".
- Thiolutin inchikey "MHMRAFONCSQAIA-UHFFFAOYAX".
- Thiolutin iupacName "N-acetamide".
- Thiolutin molecularWeight "228.293".
- Thiolutin n "2".
- Thiolutin o "2".
- Thiolutin pubchem "6870".
- Thiolutin s "2".
- Thiolutin smiles "O=CC".
- Thiolutin stdinchi "1".
- Thiolutin stdinchikey "MHMRAFONCSQAIA-UHFFFAOYSA-N".
- Thiolutin synonyms "(N-acetamide, farcinicin, propiopyvothine, acetopyrrothine)".
- Thiolutin verifiedfields "changed".
- Thiolutin verifiedrevid "470607244".
- Thiolutin width "150".
- Thiolutin wikiPageUsesTemplate Template:Drugbox.
- Thiolutin wikiPageUsesTemplate Template:Pharma-stub.
- Thiolutin subject Category:Acetamides.
- Thiolutin subject Category:Antibiotics.
- Thiolutin subject Category:Lactams.
- Thiolutin subject Category:Organic_disulfides.
- Thiolutin hypernym Antibiotic.
- Thiolutin type ChemicalSubstance.
- Thiolutin type Drug.
- Thiolutin type Amide.
- Thiolutin type Chemical.
- Thiolutin type Drug.
- Thiolutin type Heterocycle.
- Thiolutin type Lactam.
- Thiolutin type Product.
- Thiolutin type ChemicalObject.
- Thiolutin type Thing.
- Thiolutin type Q8386.
- Thiolutin comment "Thiolutin is a sulfur-containing antibiotic, which is a potent inhibitor of bacterial and yeast RNA polymerases. It was found to inhibit in vitro RNA synthesis directed by all three yeast RNA polymerases (I, II, and III). Thiolutin is also an inhibitor of mannan and glucan formation in Saccharomyces cerevisiae and used for the analysis of mRNA stability.".
- Thiolutin label "Thiolutin".
- Thiolutin sameAs m.02vp8vx.
- Thiolutin sameAs Tiolutin.
- Thiolutin sameAs Tiolutin.
- Thiolutin sameAs Q7784674.
- Thiolutin sameAs Q7784674.
- Thiolutin wasDerivedFrom Thiolutin?oldid=651358908.
- Thiolutin depiction Thiolutin.png.
- Thiolutin isPrimaryTopicOf Thiolutin.