Matches in DBpedia 2015-10 for { <http://dbpedia.org/resource/Thiolase> ?p ?o }
- Thiolase abstract "Thiolases, also known as acetyl-coenzyme A acetyltransferases (ACAT), are enzymes which convert two units of acetyl-CoA to acetoacetyl CoA in the mevalonate pathway. Thiolases are ubiquitous enzymes that have key roles in many vital biochemical pathways, including the beta oxidation pathway of fatty acid degradation and various biosynthetic pathways. Members of the thiolase family can be divided into two broad categories: degradative thiolases (EC 2.3.1.16) and biosynthetic thiolases (EC 2.3.1.9). These two different types of thiolase are found both in eukaryotes and in prokaryotes: acetoacetyl-CoA thiolase (EC:2.3.1.9) and 3-ketoacyl-CoA thiolase (EC:2.3.1.16). 3-ketoacyl-CoA thiolase (also called thiolase I) has a broad chain-length specificity for its substrates and is involved in degradative pathways such as fatty acid beta-oxidation. Acetoacetyl-CoA thiolase (also called thiolase II) is specific for the thiolysis of acetoacetyl-CoA and involved in biosynthetic pathways such as poly beta-hydroxybutyric acid synthesis or steroid biogenesis.The formation of a carbon–carbon bond is a key step in the biosynthetic pathways by which fatty acids and polyketide are made. The thiolase superfamily enzymes catalyse the carbon–carbon-bond formation via a thioester-dependent Claisen condensation reaction mechanism.".
- Thiolase symbol "Thiolase_C".
- Thiolase symbol "Thiolase_N".
- Thiolase thumbnail Mevalonate_pathway.png?width=300.
- Thiolase wikiPageID "10940038".
- Thiolase wikiPageLength "17547".
- Thiolase wikiPageOutDegree "53".
- Thiolase wikiPageRevisionID "679099429".
- Thiolase wikiPageWikiLink 3-ketoacyl-CoA.
- Thiolase wikiPageWikiLink 3-oxoadipyl-CoA_thiolase.
- Thiolase wikiPageWikiLink ACAA1.
- Thiolase wikiPageWikiLink ACAA2.
- Thiolase wikiPageWikiLink ACAT1.
- Thiolase wikiPageWikiLink ACAT2.
- Thiolase wikiPageWikiLink Acetoacetyl-CoA.
- Thiolase wikiPageWikiLink Acetoacetyl_CoA.
- Thiolase wikiPageWikiLink Acetyl-CoA.
- Thiolase wikiPageWikiLink Acetyl-CoA_C-acetyltransferase.
- Thiolase wikiPageWikiLink Acetyl-CoA_C-acyltransferase.
- Thiolase wikiPageWikiLink Acyl_carrier_protein.
- Thiolase wikiPageWikiLink Basal_ganglia.
- Thiolase wikiPageWikiLink Beta-Hydroxybutyric_acid.
- Thiolase wikiPageWikiLink Beta-hydroxybutyric_acid.
- Thiolase wikiPageWikiLink Beta-ketothiolase_deficiency.
- Thiolase wikiPageWikiLink Beta_oxidation.
- Thiolase wikiPageWikiLink Category:Protein_domains.
- Thiolase wikiPageWikiLink Claisen_condensation.
- Thiolase wikiPageWikiLink Coenzyme_A.
- Thiolase wikiPageWikiLink Cytoplasm.
- Thiolase wikiPageWikiLink Enzyme.
- Thiolase wikiPageWikiLink Enzymes.
- Thiolase wikiPageWikiLink Eukaryote.
- Thiolase wikiPageWikiLink Eukaryotes.
- Thiolase wikiPageWikiLink Eukaryotic.
- Thiolase wikiPageWikiLink Fatty_acid.
- Thiolase wikiPageWikiLink Fatty_acids.
- Thiolase wikiPageWikiLink HADHB.
- Thiolase wikiPageWikiLink Ketoacidosis.
- Thiolase wikiPageWikiLink Ketone_bodies.
- Thiolase wikiPageWikiLink Ketone_body.
- Thiolase wikiPageWikiLink MRI.
- Thiolase wikiPageWikiLink Magnetic_resonance_imaging.
- Thiolase wikiPageWikiLink Mevalonate_pathway.
- Thiolase wikiPageWikiLink Mitochondria.
- Thiolase wikiPageWikiLink Mitochondrion.
- Thiolase wikiPageWikiLink Necrosis.
- Thiolase wikiPageWikiLink Pantetheine.
- Thiolase wikiPageWikiLink Peroxisome.
- Thiolase wikiPageWikiLink Peroxisomes.
- Thiolase wikiPageWikiLink Polyketide.
- Thiolase wikiPageWikiLink Prokaryote.
- Thiolase wikiPageWikiLink Prokaryotes.
- Thiolase wikiPageWikiLink Propanoyl-CoA_C-acyltransferase.
- Thiolase wikiPageWikiLink Propionyl-CoA_C2-trimethyltridecanoyltransferase.
- Thiolase wikiPageWikiLink Protein_dimer.
- Thiolase wikiPageWikiLink Protein_family.
- Thiolase wikiPageWikiLink SCP2.
- Thiolase wikiPageWikiLink Steroid.
- Thiolase wikiPageWikiLink Tetrameters.
- Thiolase wikiPageWikiLink Thioester.
- Thiolase wikiPageWikiLink Thioesters.
- Thiolase wikiPageWikiLink File:Mevalonate_pathway.png.
- Thiolase wikiPageWikiLink File:Thioalse_Reaction_Catalysis.gif.
- Thiolase wikiPageWikiLink File:Thiolase_Mechanisim.gif.
- Thiolase wikiPageWikiLinkText "Thiolase".
- Thiolase wikiPageWikiLinkText "Thiolase#Isozymes".
- Thiolase wikiPageWikiLinkText "thiolase".
- Thiolase cdd "cd00751".
- Thiolase hasPhotoCollection Thiolase.
- Thiolase interpro "IPR002155".
- Thiolase name "Thiolase, C-terminal domain".
- Thiolase name "Thiolase, N-terminal domain".
- Thiolase pfam "PF00108".
- Thiolase pfam "PF02803".
- Thiolase prosite "PDOC00092".
- Thiolase scop "1".
- Thiolase symbol "Thiolase_C".
- Thiolase symbol "Thiolase_N".
- Thiolase wikiPageUsesTemplate Template:Acyltransferases.
- Thiolase wikiPageUsesTemplate Template:Distinguish.
- Thiolase wikiPageUsesTemplate Template:EC_number.
- Thiolase wikiPageUsesTemplate Template:InterPro_content.
- Thiolase wikiPageUsesTemplate Template:MeshName.
- Thiolase wikiPageUsesTemplate Template:Mevalonate_pathway.
- Thiolase wikiPageUsesTemplate Template:Pfam_box.
- Thiolase wikiPageUsesTemplate Template:Reflist.
- Thiolase subject Category:Protein_domains.
- Thiolase hypernym Enzymes.
- Thiolase type Article.
- Thiolase type Biomolecule.
- Thiolase type Protein.
- Thiolase type Article.
- Thiolase type Domain.
- Thiolase type Thing.
- Thiolase type Q206229.
- Thiolase type Q8054.
- Thiolase comment "Thiolases, also known as acetyl-coenzyme A acetyltransferases (ACAT), are enzymes which convert two units of acetyl-CoA to acetoacetyl CoA in the mevalonate pathway. Thiolases are ubiquitous enzymes that have key roles in many vital biochemical pathways, including the beta oxidation pathway of fatty acid degradation and various biosynthetic pathways.".
- Thiolase label "Thiolase".
- Thiolase differentFrom HADHB.
- Thiolase differentFrom Sterol_O-acyltransferase.