Matches in DBpedia 2015-10 for { <http://dbpedia.org/resource/Tet_methylcytosine_dioxygenase_2> ?p ?o }
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- Tet_methylcytosine_dioxygenase_2 abstract "Template:PBB/54790Tet methylcytosine dioxygenase 2 (TET2) is a human gene. TET2 encodes a protein that catalyzes the conversion of the modified DNA base methylcytosine to 5-hydroxymethylcytosine. Mutations in this gene were first identified in myeloid neoplasms with deletion or uniparental disomy at 4q24. TET2 may also be a candidate for active DNA demethylation, the catalytic removal of the methyl group added to the fifth carbon on the cytosine base.TET2 resides at chromosome 4q24, in a region showing recurrent microdeletions and copy-neutral loss of heterozygosity (CN-LOH) in patients with diverse myeloid malignancies. Somatic TET2 mutations are frequently observed in myelodysplastic syndromes (MDS), myeloproliferative neoplasms (MPN), MDS/MPN overlap syndromes including chronic myelomonocytic leukaemia (CMML), acute myeloid leukaemias (AML) and secondary AML (sAML). TET2 mutations have prognostic value in cytogenetically normal acute myeloid leukemia (CN-AML). "Nonsense" and "frameshift" mutations in this gene are associated with poor outcome on standard therapies in this otherwise favorable-risk patient subset.".
- Tet_methylcytosine_dioxygenase_2 entrezgene "54790".
- Tet_methylcytosine_dioxygenase_2 wikiPageID "36916897".
- Tet_methylcytosine_dioxygenase_2 wikiPageLength "7342".
- Tet_methylcytosine_dioxygenase_2 wikiPageOutDegree "14".
- Tet_methylcytosine_dioxygenase_2 wikiPageRevisionID "678234509".
- Tet_methylcytosine_dioxygenase_2 wikiPageWikiLink Acute_myeloid_leukaemia.
- Tet_methylcytosine_dioxygenase_2 wikiPageWikiLink Acute_myeloid_leukemia.
- Tet_methylcytosine_dioxygenase_2 wikiPageWikiLink Catalysis.
- Tet_methylcytosine_dioxygenase_2 wikiPageWikiLink Category:Human_genes.
- Tet_methylcytosine_dioxygenase_2 wikiPageWikiLink Chromosome.
- Tet_methylcytosine_dioxygenase_2 wikiPageWikiLink Chronic_myelomonocytic_leukaemia.
- Tet_methylcytosine_dioxygenase_2 wikiPageWikiLink Chronic_myelomonocytic_leukemia.
- Tet_methylcytosine_dioxygenase_2 wikiPageWikiLink DNA.
- Tet_methylcytosine_dioxygenase_2 wikiPageWikiLink DNA_demethylation.
- Tet_methylcytosine_dioxygenase_2 wikiPageWikiLink Gene.
- Tet_methylcytosine_dioxygenase_2 wikiPageWikiLink Heterozygosity.
- Tet_methylcytosine_dioxygenase_2 wikiPageWikiLink Myelodysplastic_syndrome.
- Tet_methylcytosine_dioxygenase_2 wikiPageWikiLink Myeloid.
- Tet_methylcytosine_dioxygenase_2 wikiPageWikiLink Myeloproliferative_neoplasm.
- Tet_methylcytosine_dioxygenase_2 wikiPageWikiLink Myeloproliferative_neoplasms.
- Tet_methylcytosine_dioxygenase_2 wikiPageWikiLink Neoplasm.
- Tet_methylcytosine_dioxygenase_2 wikiPageWikiLink Zygosity.
- Tet_methylcytosine_dioxygenase_2 wikiPageWikiLinkText "Tet methylcytosine dioxygenase 2".
- Tet_methylcytosine_dioxygenase_2 hasPhotoCollection Tet_methylcytosine_dioxygenase_2.
- Tet_methylcytosine_dioxygenase_2 wikiPageUsesTemplate Template:Cite_journal.
- Tet_methylcytosine_dioxygenase_2 wikiPageUsesTemplate Template:PBB.
- Tet_methylcytosine_dioxygenase_2 wikiPageUsesTemplate Template:Refbegin.
- Tet_methylcytosine_dioxygenase_2 wikiPageUsesTemplate Template:Refend.
- Tet_methylcytosine_dioxygenase_2 wikiPageUsesTemplate Template:Reflist.
- Tet_methylcytosine_dioxygenase_2 subject Category:Human_genes.
- Tet_methylcytosine_dioxygenase_2 hypernym Gene.
- Tet_methylcytosine_dioxygenase_2 type Article.
- Tet_methylcytosine_dioxygenase_2 type Biomolecule.
- Tet_methylcytosine_dioxygenase_2 type Protein.
- Tet_methylcytosine_dioxygenase_2 type Article.
- Tet_methylcytosine_dioxygenase_2 type Thing.
- Tet_methylcytosine_dioxygenase_2 type Q206229.
- Tet_methylcytosine_dioxygenase_2 type Q8054.
- Tet_methylcytosine_dioxygenase_2 comment "Template:PBB/54790Tet methylcytosine dioxygenase 2 (TET2) is a human gene. TET2 encodes a protein that catalyzes the conversion of the modified DNA base methylcytosine to 5-hydroxymethylcytosine. Mutations in this gene were first identified in myeloid neoplasms with deletion or uniparental disomy at 4q24.".
- Tet_methylcytosine_dioxygenase_2 label "Tet methylcytosine dioxygenase 2".
- Tet_methylcytosine_dioxygenase_2 sameAs m.0m0qhzr.
- Tet_methylcytosine_dioxygenase_2 sameAs Q7705980.
- Tet_methylcytosine_dioxygenase_2 sameAs Q7705980.
- Tet_methylcytosine_dioxygenase_2 wasDerivedFrom Tet_methylcytosine_dioxygenase_2?oldid=678234509.
- Tet_methylcytosine_dioxygenase_2 isPrimaryTopicOf Tet_methylcytosine_dioxygenase_2.