Matches in DBpedia 2015-10 for { <http://dbpedia.org/resource/Targeted_therapy> ?p ?o }
- Targeted_therapy abstract "Targeted therapy or molecularly targeted therapy is one of the major modalities of medical treatment (pharmacotherapy) for cancer, others being hormonal therapy and cytotoxic chemotherapy. As a form of molecular medicine, targeted therapy blocks the growth of cancer cells by interfering with specific targeted molecules needed for carcinogenesis and tumor growth, rather than by simply interfering with all rapidly dividing cells (e.g. with traditional chemotherapy). Because most agents for targeted therapy are biopharmaceuticals, the term biologic therapy is sometimes synonymous with targeted therapy when used in the context of cancer therapy (and thus distinguished from chemotherapy, that is, cytotoxic therapy). However, the modalities can be combined; antibody-drug conjugates combine biologic and cytotoxic mechanisms into one targeted therapy.Targeted cancer therapies are expected to be more effective than older forms of treatments and less harmful to normal cells. Many targeted therapies are examples of immunotherapy (using immune mechanisms for therapeutic goals) developed by the field of cancer immunology. Thus, as immunomodulators, they are one type of biological response modifiers. There are targeted therapies for breast cancer, multiple myeloma, lymphoma, prostate cancer, melanoma and other cancers.The definitive experiments that showed that targeted therapy would reverse the malignant phenotype of tumor cells involved treating Her2/neu transformed cells with monoclonal antibodies in vitro and in vivo by Mark Greene’s laboratory and reported from 1985.Some have challenged the use of the term, stating that drugs usually associated with the term are insufficiently selective. The phrase occasionally appears in scare quotes: "targeted therapy". Targeted therapies may also be described as "chemotherapy" or "non-cytotoxic chemotherapy", as "chemotherapy" strictly means only "treatment by chemicals". But in typical medical and general usage "chemotherapy" is now mostly used specifically for "traditional" cytotoxic chemotherapy.".
- Targeted_therapy thumbnail Mechanism_imatinib.svg?width=300.
- Targeted_therapy wikiPageExternalLink 2191.
- Targeted_therapy wikiPageExternalLink mtdp.
- Targeted_therapy wikiPageExternalLink targeted.
- Targeted_therapy wikiPageExternalLink www.cancerdriver.com.
- Targeted_therapy wikiPageExternalLink issue11.
- Targeted_therapy wikiPageExternalLink import.mmmp?page=targetedtherapydatabase.mmmp.
- Targeted_therapy wikiPageExternalLink welcome.mmmp.
- Targeted_therapy wikiPageID "3084027".
- Targeted_therapy wikiPageLength "12725".
- Targeted_therapy wikiPageOutDegree "125".
- Targeted_therapy wikiPageRevisionID "680321921".
- Targeted_therapy wikiPageWikiLink ADEPT_(medicine).
- Targeted_therapy wikiPageWikiLink ALK_inhibitor.
- Targeted_therapy wikiPageWikiLink AN-152.
- Targeted_therapy wikiPageWikiLink Alemtuzumab.
- Targeted_therapy wikiPageWikiLink Antibody-drug_conjugate.
- Targeted_therapy wikiPageWikiLink Apatinib.
- Targeted_therapy wikiPageWikiLink Apoptosis.
- Targeted_therapy wikiPageWikiLink BRAF_(gene).
- Targeted_therapy wikiPageWikiLink Bcl-2.
- Targeted_therapy wikiPageWikiLink Bcl-2_inhibitor.
- Targeted_therapy wikiPageWikiLink Bevacizumab.
- Targeted_therapy wikiPageWikiLink Binimetinib.
- Targeted_therapy wikiPageWikiLink Biological_response_modifiers.
- Targeted_therapy wikiPageWikiLink Biopharmaceutical.
- Targeted_therapy wikiPageWikiLink Bortezomib.
- Targeted_therapy wikiPageWikiLink Braf_inhibitor.
- Targeted_therapy wikiPageWikiLink Brain_tumor.
- Targeted_therapy wikiPageWikiLink Breast_cancer.
- Targeted_therapy wikiPageWikiLink CD20.
- Targeted_therapy wikiPageWikiLink CDK_inhibitor.
- Targeted_therapy wikiPageWikiLink Cancer.
- Targeted_therapy wikiPageWikiLink Cancer_cell.
- Targeted_therapy wikiPageWikiLink Cancer_immunology.
- Targeted_therapy wikiPageWikiLink Cancer_stem_cell.
- Targeted_therapy wikiPageWikiLink Cancer_stem_cells.
- Targeted_therapy wikiPageWikiLink Carcinogenesis.
- Targeted_therapy wikiPageWikiLink Category:Antineoplastic_drugs.
- Targeted_therapy wikiPageWikiLink Category:Drugs.
- Targeted_therapy wikiPageWikiLink Cetuximab.
- Targeted_therapy wikiPageWikiLink Chemotherapy.
- Targeted_therapy wikiPageWikiLink Chronic_myelogenous_leukemia.
- Targeted_therapy wikiPageWikiLink Colon_cancer.
- Targeted_therapy wikiPageWikiLink Colorectal_cancer.
- Targeted_therapy wikiPageWikiLink Crizotinib.
- Targeted_therapy wikiPageWikiLink Cytotoxic.
- Targeted_therapy wikiPageWikiLink Cytotoxicity.
- Targeted_therapy wikiPageWikiLink DEPT_(medicine).
- Targeted_therapy wikiPageWikiLink Dabrafenib.
- Targeted_therapy wikiPageWikiLink Dasatinib.
- Targeted_therapy wikiPageWikiLink Dermatofibrosarcoma_protuberans.
- Targeted_therapy wikiPageWikiLink Doxorubicin.
- Targeted_therapy wikiPageWikiLink Epidermal_growth_factor_receptor.
- Targeted_therapy wikiPageWikiLink Erlotinib.
- Targeted_therapy wikiPageWikiLink Everolimus.
- Targeted_therapy wikiPageWikiLink Gastric_carcinoma.
- Targeted_therapy wikiPageWikiLink Gastrointestinal_stromal_tumor.
- Targeted_therapy wikiPageWikiLink Gefitinib.
- Targeted_therapy wikiPageWikiLink Gonadotropin-releasing_hormone.
- Targeted_therapy wikiPageWikiLink Gossypol.
- Targeted_therapy wikiPageWikiLink neu.
- Targeted_therapy wikiPageWikiLink Hepatocellular_carcinoma.
- Targeted_therapy wikiPageWikiLink neu.
- Targeted_therapy wikiPageWikiLink History_of_cancer_chemotherapy.
- Targeted_therapy wikiPageWikiLink Hormonal_therapy_(oncology).
- Targeted_therapy wikiPageWikiLink Hsp90_inhibitor.
- Targeted_therapy wikiPageWikiLink Imatinib.
- Targeted_therapy wikiPageWikiLink Immunomodulator.
- Targeted_therapy wikiPageWikiLink Immunotherapy.
- Targeted_therapy wikiPageWikiLink Ipilimumab.
- Targeted_therapy wikiPageWikiLink Janus_kinase_inhibitor.
- Targeted_therapy wikiPageWikiLink Journal_of_Clinical_Oncology.
- Targeted_therapy wikiPageWikiLink LEE011.
- Targeted_therapy wikiPageWikiLink LGX818.
- Targeted_therapy wikiPageWikiLink LHRH.
- Targeted_therapy wikiPageWikiLink Labile_cell.
- Targeted_therapy wikiPageWikiLink Lapatinib.
- Targeted_therapy wikiPageWikiLink Lung_cancer.
- Targeted_therapy wikiPageWikiLink Lymphoma.
- Targeted_therapy wikiPageWikiLink MEK162.
- Targeted_therapy wikiPageWikiLink MEK_inhibitor.
- Targeted_therapy wikiPageWikiLink Melanoma.
- Targeted_therapy wikiPageWikiLink Molecular_medicine.
- Targeted_therapy wikiPageWikiLink Molecule.
- Targeted_therapy wikiPageWikiLink Monoclonal_antibody.
- Targeted_therapy wikiPageWikiLink Multiple_myeloma.
- Targeted_therapy wikiPageWikiLink National_Cancer_Institute.
- Targeted_therapy wikiPageWikiLink Navitoclax.
- Targeted_therapy wikiPageWikiLink Neoplasm.
- Targeted_therapy wikiPageWikiLink Nilotinib.
- Targeted_therapy wikiPageWikiLink Non-small-cell_lung_carcinoma.
- Targeted_therapy wikiPageWikiLink Non-small_cell_lung_cancer.
- Targeted_therapy wikiPageWikiLink Obatoclax.
- Targeted_therapy wikiPageWikiLink PARP_inhibitor.
- Targeted_therapy wikiPageWikiLink PD-0332991.
- Targeted_therapy wikiPageWikiLink PI3K_inhibitor.
- Targeted_therapy wikiPageWikiLink Palbociclib.
- Targeted_therapy wikiPageWikiLink Panitumumab.