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- TSG-6 abstract "Tumor necrosis factor-inducible gene 6 protein also known as TNF-stimulated gene 6 protein or TSG-6 is a protein that in humans is encoded by the TNFAIP6 (tumor necrosis factor, alpha-induced protein 6) gene.TSG-6 is a 30 kDa secreted protein that contains a hyaluronan-binding LINK domain a and thus is a member of the hyaluronan-binding protein family, also called hyaladherins. The hyaluronan-binding domain is known to be involved in extracellular matrix stability and cell migration. This protein has been shown to form a stable, covalent complex with inter-alpha-inhibitor (IαI), and thus enhance the serine protease inhibitory activity of IαI, which is important in the protease network associated with inflammation. The expression of this gene can be induced by a number of signalling molecules, principally tumor necrosis factor α (TNF-α) and interleukin-1 (IL-1). The expression can also be induced by mechanical stimuli in vascular smooth muscle cells, and is found to be correlated with proteoglycan synthesis and aggregation.TSG-6 also interacts with a plethora of matrix associated molecules, such an aggrecan, versican, thrombospondin (1&2), pentraxin-3 and fibronectin.".
- TSG-6 entrezgene "7130".
- TSG-6 wikiPageID "15044047".
- TSG-6 wikiPageLength "8306".
- TSG-6 wikiPageOutDegree "17".
- TSG-6 wikiPageRevisionID "679094434".
- TSG-6 wikiPageWikiLink Aggrecan.
- TSG-6 wikiPageWikiLink Atomic_mass_unit.
- TSG-6 wikiPageWikiLink Cell_migration.
- TSG-6 wikiPageWikiLink Covalent.
- TSG-6 wikiPageWikiLink Covalent_bond.
- TSG-6 wikiPageWikiLink Extracellular_matrix.
- TSG-6 wikiPageWikiLink Fibronectin.
- TSG-6 wikiPageWikiLink Gene.
- TSG-6 wikiPageWikiLink Hyaluronan.
- TSG-6 wikiPageWikiLink Hyaluronic_acid.
- TSG-6 wikiPageWikiLink ITIH1.
- TSG-6 wikiPageWikiLink Interleukin_1.
- TSG-6 wikiPageWikiLink Interleukin_1_family.
- TSG-6 wikiPageWikiLink PTX3.
- TSG-6 wikiPageWikiLink Protein.
- TSG-6 wikiPageWikiLink Proteoglycan.
- TSG-6 wikiPageWikiLink Serine_protease.
- TSG-6 wikiPageWikiLink Thrombospondin.
- TSG-6 wikiPageWikiLink Tumor_necrosis_factor-alpha.
- TSG-6 wikiPageWikiLink Tumor_necrosis_factor_alpha.
- TSG-6 wikiPageWikiLink Versican.
- TSG-6 wikiPageWikiLinkText "TSG-6".
- TSG-6 hasPhotoCollection TSG-6.
- TSG-6 requireManualInspection "no".
- TSG-6 updateCitations "no".
- TSG-6 updatePage "no".
- TSG-6 updateProteinBox "no".
- TSG-6 updateSummary "no".
- TSG-6 wikiPageUsesTemplate Template:Gene-2-stub.
- TSG-6 wikiPageUsesTemplate Template:PBB.
- TSG-6 wikiPageUsesTemplate Template:PBB_Controls.
- TSG-6 wikiPageUsesTemplate Template:PBB_Further_reading.
- TSG-6 wikiPageUsesTemplate Template:PDB_Gallery.
- TSG-6 wikiPageUsesTemplate Template:Refbegin.
- TSG-6 wikiPageUsesTemplate Template:Refend.
- TSG-6 wikiPageUsesTemplate Template:Reflist.
- TSG-6 hypernym Protein.
- TSG-6 type Biomolecule.
- TSG-6 type Protein.
- TSG-6 type Thing.
- TSG-6 type Q206229.
- TSG-6 type Q8054.
- TSG-6 comment "Tumor necrosis factor-inducible gene 6 protein also known as TNF-stimulated gene 6 protein or TSG-6 is a protein that in humans is encoded by the TNFAIP6 (tumor necrosis factor, alpha-induced protein 6) gene.TSG-6 is a 30 kDa secreted protein that contains a hyaluronan-binding LINK domain a and thus is a member of the hyaluronan-binding protein family, also called hyaladherins. The hyaluronan-binding domain is known to be involved in extracellular matrix stability and cell migration.".
- TSG-6 label "TSG-6".
- TSG-6 sameAs m.03h5rqf.
- TSG-6 sameAs Q7671583.
- TSG-6 sameAs Q7671583.
- TSG-6 wasDerivedFrom TSG-6?oldid=679094434.
- TSG-6 isPrimaryTopicOf TSG-6.