Matches in DBpedia 2015-10 for { <http://dbpedia.org/resource/TRPML> ?p ?o }
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- TRPML abstract "TRPML (transient receptor potential cation channel, mucolipin subfamily) comprises a group of three evolutionarily related proteins that belongs to the large family of transient receptor potential ion channels. The three proteins TRPML1, TRPML2 and TRPML3 are encoded by the mucolipin-1 (MCOLN1), mucolipin-2 (MCOLN2) and mucolipin-3 (MCOLN3) genes, respectively. The three members of the TRPML ("ML" for mucolipin) sub-family are not extremely well characterized. TRPML1 is known to be localized in late endosomes. This subunit also contains a lipase domain between its S1 and S2 segments. While the function of this domain is unknown it has been proposed that it is involved in channel regulation. Physiological studies have described TRPML1 channels as proton leak channels in lysosomes responsible for preventing these organelles from becoming too acidic. TRPML2 and TRPML3 more poorly characterized than TRPML1.Deficiencies can lead to enlarged vesicles.".
- TRPML wikiPageExternalLink FamilyMenuForward?familyId=12.
- TRPML wikiPageExternalLink www.trpchannel.org.
- TRPML wikiPageID "11896846".
- TRPML wikiPageLength "3689".
- TRPML wikiPageOutDegree "20".
- TRPML wikiPageRevisionID "593219499".
- TRPML wikiPageWikiLink Category:Ion_channels.
- TRPML wikiPageWikiLink Category:Membrane_biology.
- TRPML wikiPageWikiLink Endosome.
- TRPML wikiPageWikiLink Ion_channel.
- TRPML wikiPageWikiLink Lysosome.
- TRPML wikiPageWikiLink MCOLN1.
- TRPML wikiPageWikiLink MCOLN2.
- TRPML wikiPageWikiLink MCOLN3.
- TRPML wikiPageWikiLink Mucolipin-1.
- TRPML wikiPageWikiLink Proton.
- TRPML wikiPageWikiLink TRPML1.
- TRPML wikiPageWikiLink TRPML2.
- TRPML wikiPageWikiLink TRPML3.
- TRPML wikiPageWikiLink Transient_receptor_potential.
- TRPML wikiPageWikiLink Transient_receptor_potential_channel.
- TRPML wikiPageWikiLinkText "TRPML".
- TRPML hasPhotoCollection TRPML.
- TRPML wikiPageUsesTemplate Template:Cite_web.
- TRPML wikiPageUsesTemplate Template:Gene.
- TRPML wikiPageUsesTemplate Template:Ion_channels.
- TRPML wikiPageUsesTemplate Template:Reflist.
- TRPML subject Category:Ion_channels.
- TRPML subject Category:Membrane_biology.
- TRPML type Biophysic.
- TRPML type Channel.
- TRPML comment "TRPML (transient receptor potential cation channel, mucolipin subfamily) comprises a group of three evolutionarily related proteins that belongs to the large family of transient receptor potential ion channels. The three proteins TRPML1, TRPML2 and TRPML3 are encoded by the mucolipin-1 (MCOLN1), mucolipin-2 (MCOLN2) and mucolipin-3 (MCOLN3) genes, respectively. The three members of the TRPML ("ML" for mucolipin) sub-family are not extremely well characterized.".
- TRPML label "TRPML".
- TRPML sameAs m.02rx6ck.
- TRPML sameAs Q7671483.
- TRPML sameAs Q7671483.
- TRPML wasDerivedFrom TRPML?oldid=593219499.
- TRPML isPrimaryTopicOf TRPML.