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- Spectrin,_alpha_1 abstract "Spectrin alpha chain, erythrocyte is a protein that in humans is encoded by the SPTA1 gene.Spectrin is an actin crosslinking and molecular scaffold protein that links the plasma membrane to the actin cytoskeleton, and functions in the determination of cell shape, arrangement of transmembrane proteins, and organization of organelles. It is a tetramer made up of alpha-beta dimers linked in a head-to-head arrangement. This gene is one member of a family of alpha-spectrin genes. The encoded protein is primarily composed of 22 spectrin repeats which are involved in dimer formation. It forms weaker tetramer interactions than non-erythrocytic alpha spectrin, which may increase the plasma membrane elasticity and deformability of red blood cells. Mutations in this gene result in a variety of hereditary red blood cell disorders, including elliptocytosis type 2, pyropoikilocytosis, and spherocytic hemolytic anemia.".
- Spectrin,_alpha_1 entrezgene "6708".
- Spectrin,_alpha_1 wikiPageID "14722840".
- Spectrin,_alpha_1 wikiPageLength "8436".
- Spectrin,_alpha_1 wikiPageOutDegree "4".
- Spectrin,_alpha_1 wikiPageRevisionID "679086570".
- Spectrin,_alpha_1 wikiPageWikiLink ABL_(gene).
- Spectrin,_alpha_1 wikiPageWikiLink Abl_gene.
- Spectrin,_alpha_1 wikiPageWikiLink Gene.
- Spectrin,_alpha_1 wikiPageWikiLink Protein.
- Spectrin,_alpha_1 wikiPageWikiLink Protein-protein_interaction.
- Spectrin,_alpha_1 wikiPageWikiLink Protein–protein_interaction.
- Spectrin,_alpha_1 wikiPageWikiLinkText "SPTA".
- Spectrin,_alpha_1 wikiPageWikiLinkText "SPTA1".
- Spectrin,_alpha_1 wikiPageWikiLinkText "Spectrin, alpha 1".
- Spectrin,_alpha_1 wikiPageWikiLinkText "alpha-spectrin".
- Spectrin,_alpha_1 hasPhotoCollection Spectrin,_alpha_1.
- Spectrin,_alpha_1 requireManualInspection "no".
- Spectrin,_alpha_1 summaryText "Spectrin is an actin crosslinking and molecular scaffold protein that links the plasma membrane to the actin cytoskeleton, and functions in the determination of cell shape, arrangement of transmembrane proteins, and organization of organelles. It is a tetramer made up of alpha-beta dimers linked in a head-to-head arrangement. This gene is one member of a family of alpha-spectrin genes. The encoded protein is primarily composed of 22 spectrin repeats which are involved in dimer formation. It forms weaker tetramer interactions than non-erythrocytic alpha spectrin, which may increase the plasma membrane elasticity and deformability of red blood cells. Mutations in this gene result in a variety of hereditary red blood cell disorders, including elliptocytosis type 2, pyropoikilocytosis, and spherocytic hemolytic anemia.".
- Spectrin,_alpha_1 updateCitations "yes".
- Spectrin,_alpha_1 updatePage "yes".
- Spectrin,_alpha_1 updateProteinBox "yes".
- Spectrin,_alpha_1 updateSummary "yes".
- Spectrin,_alpha_1 wikiPageUsesTemplate Template:Cytoskeletal_Proteins.
- Spectrin,_alpha_1 wikiPageUsesTemplate Template:Gene-1-stub.
- Spectrin,_alpha_1 wikiPageUsesTemplate Template:PBB.
- Spectrin,_alpha_1 wikiPageUsesTemplate Template:PBB_Controls.
- Spectrin,_alpha_1 wikiPageUsesTemplate Template:PBB_Further_reading.
- Spectrin,_alpha_1 wikiPageUsesTemplate Template:PBB_Summary.
- Spectrin,_alpha_1 wikiPageUsesTemplate Template:PDB_Gallery.
- Spectrin,_alpha_1 wikiPageUsesTemplate Template:Refbegin.
- Spectrin,_alpha_1 wikiPageUsesTemplate Template:Refend.
- Spectrin,_alpha_1 wikiPageUsesTemplate Template:Reflist.
- Spectrin,_alpha_1 wikiPageUsesTemplate Template:Use_dmy_dates.
- Spectrin,_alpha_1 hypernym Protein.
- Spectrin,_alpha_1 type Biomolecule.
- Spectrin,_alpha_1 type Protein.
- Spectrin,_alpha_1 type Thing.
- Spectrin,_alpha_1 type Q206229.
- Spectrin,_alpha_1 type Q8054.
- Spectrin,_alpha_1 comment "Spectrin alpha chain, erythrocyte is a protein that in humans is encoded by the SPTA1 gene.Spectrin is an actin crosslinking and molecular scaffold protein that links the plasma membrane to the actin cytoskeleton, and functions in the determination of cell shape, arrangement of transmembrane proteins, and organization of organelles. It is a tetramer made up of alpha-beta dimers linked in a head-to-head arrangement. This gene is one member of a family of alpha-spectrin genes.".
- Spectrin,_alpha_1 label "Spectrin, alpha 1".
- Spectrin,_alpha_1 sameAs m.03gvjyx.
- Spectrin,_alpha_1 sameAs Q7575236.
- Spectrin,_alpha_1 sameAs Q7575236.
- Spectrin,_alpha_1 wasDerivedFrom Spectrin,_alpha_1?oldid=679086570.
- Spectrin,_alpha_1 isPrimaryTopicOf Spectrin,_alpha_1.