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- Small_GTPase abstract "Small GTPases (EC 3.6.5.2) are a family of hydrolase enzymes that can bind and hydrolyze guanosine triphosphate (GTP). They are a type of G-proteins found in the cytosol that are homologous to the alpha subunit of heterotrimeric G-proteins, but unlike the alpha subunit of G proteins, a small GTPase can function independently as a hydrolase enzyme to bind to and hydrolyze a guanosine triphosphate (GTP) to form guanosine diphosphate (GDP). The most well-known members are the Ras GTPases and hence they are sometimes called Ras superfamily GTPases.A typical G-protein is active when bound to GTP and inactive when bound to GDP (i.e. when the GTP is hydrolyzed to GDP). The GDP can be then replaced by free GTP. Therefore, a G-protein can be switched on and off. GTP hydrolysis is accelerated by GTPase activating proteins (GAPs), while GTP exchange is catalyzed by Guanine nucleotide exchange factors (GEFs). Activation of a GEF typically activates its cognate G-protein, while activation of a GAP results in inactivation of the cognate G-protein.Guanosine nucleotide dissociation inhibitors (GDI) maintain small GTP-ases in the inactive state.Small GTPases regulate a wide variety of processes in the cell, including growth, cellular differentiation, cell movement and lipid vesicle transport.".
- Small_GTPase ecNumber "3.6.5.2".
- Small_GTPase wikiPageID "395744".
- Small_GTPase wikiPageLength "4071".
- Small_GTPase wikiPageOutDegree "33".
- Small_GTPase wikiPageRevisionID "667697457".
- Small_GTPase wikiPageWikiLink ADP_ribosylation_factor.
- Small_GTPase wikiPageWikiLink Category:EC_3.6.5.
- Small_GTPase wikiPageWikiLink Category:Peripheral_membrane_proteins.
- Small_GTPase wikiPageWikiLink Cell_(biology).
- Small_GTPase wikiPageWikiLink Cellular_differentiation.
- Small_GTPase wikiPageWikiLink Cytosol.
- Small_GTPase wikiPageWikiLink Enzyme.
- Small_GTPase wikiPageWikiLink Enzymes.
- Small_GTPase wikiPageWikiLink G-protein.
- Small_GTPase wikiPageWikiLink GTP-binding_protein_regulators.
- Small_GTPase wikiPageWikiLink GTPase-activating_protein.
- Small_GTPase wikiPageWikiLink GTPase-activating_proteins.
- Small_GTPase wikiPageWikiLink G_protein.
- Small_GTPase wikiPageWikiLink Guanine_nucleotide_exchange_factor.
- Small_GTPase wikiPageWikiLink Guanine_nucleotide_exchange_factors.
- Small_GTPase wikiPageWikiLink Guanosine_diphosphate.
- Small_GTPase wikiPageWikiLink Guanosine_nucleotide_dissociation_inhibitor.
- Small_GTPase wikiPageWikiLink Guanosine_nucleotide_dissociation_inhibitors.
- Small_GTPase wikiPageWikiLink Guanosine_triphosphate.
- Small_GTPase wikiPageWikiLink Heterotrimeric_G-protein.
- Small_GTPase wikiPageWikiLink Heterotrimeric_G_protein.
- Small_GTPase wikiPageWikiLink Homology_(biology).
- Small_GTPase wikiPageWikiLink Hydrolase.
- Small_GTPase wikiPageWikiLink Hydrolysis.
- Small_GTPase wikiPageWikiLink Hydrolyze.
- Small_GTPase wikiPageWikiLink IQGAP.
- Small_GTPase wikiPageWikiLink IQ_motif_containing_GTPase_activating_protein.
- Small_GTPase wikiPageWikiLink Lipid.
- Small_GTPase wikiPageWikiLink Molecular_binding.
- Small_GTPase wikiPageWikiLink RHEB.
- Small_GTPase wikiPageWikiLink RRAD.
- Small_GTPase wikiPageWikiLink Rab_(G-protein).
- Small_GTPase wikiPageWikiLink Ral.
- Small_GTPase wikiPageWikiLink Ran_(biology).
- Small_GTPase wikiPageWikiLink Ran_(gene).
- Small_GTPase wikiPageWikiLink Rap_GTP-binding_protein.
- Small_GTPase wikiPageWikiLink Ras_(protein).
- Small_GTPase wikiPageWikiLink Ras_subfamily.
- Small_GTPase wikiPageWikiLink Rheb.
- Small_GTPase wikiPageWikiLink Rho_family_of_GTPases.
- Small_GTPase wikiPageWikiLink Rit_GTP-binding_protein.
- Small_GTPase wikiPageWikiLink Vesicle_(biology).
- Small_GTPase wikiPageWikiLink Vesicle_(biology_and_chemistry).
- Small_GTPase wikiPageWikiLink Wiskott-Aldrich_syndrome_protein.
- Small_GTPase wikiPageWikiLink Wiskott–Aldrich_syndrome_protein.
- Small_GTPase wikiPageWikiLinkText "Small GTPase".
- Small_GTPase wikiPageWikiLinkText "Small GTPase#The Ras superfamily".
- Small_GTPase wikiPageWikiLinkText "small G protein".
- Small_GTPase wikiPageWikiLinkText "small G-proteins".
- Small_GTPase wikiPageWikiLinkText "small GTP-ase".
- Small_GTPase wikiPageWikiLinkText "small GTPase".
- Small_GTPase wikiPageWikiLinkText "small monomeric GTPases".
- Small_GTPase ecNumber "3.6".
- Small_GTPase hasPhotoCollection Small_GTPase.
- Small_GTPase iubmbEcNumber "3".
- Small_GTPase name "Small monomeric GTPase".
- Small_GTPase wikiPageUsesTemplate Template:EC_number.
- Small_GTPase wikiPageUsesTemplate Template:GTPases.
- Small_GTPase wikiPageUsesTemplate Template:Infobox_enzyme.
- Small_GTPase wikiPageUsesTemplate Template:Intracellular_signaling_peptides_and_proteins.
- Small_GTPase wikiPageUsesTemplate Template:Main.
- Small_GTPase wikiPageUsesTemplate Template:MeshName.
- Small_GTPase wikiPageUsesTemplate Template:Reflist.
- Small_GTPase wikiPageUsesTemplate Template:Vesicular_transport_proteins.
- Small_GTPase subject Category:EC_3.6.5.
- Small_GTPase subject Category:Peripheral_membrane_proteins.
- Small_GTPase hypernym Family.
- Small_GTPase type Article.
- Small_GTPase type Biomolecule.
- Small_GTPase type Enzyme.
- Small_GTPase type Article.
- Small_GTPase type Page.
- Small_GTPase type Thing.
- Small_GTPase type Q206229.
- Small_GTPase type Q8047.
- Small_GTPase comment "Small GTPases (EC 3.6.5.2) are a family of hydrolase enzymes that can bind and hydrolyze guanosine triphosphate (GTP). They are a type of G-proteins found in the cytosol that are homologous to the alpha subunit of heterotrimeric G-proteins, but unlike the alpha subunit of G proteins, a small GTPase can function independently as a hydrolase enzyme to bind to and hydrolyze a guanosine triphosphate (GTP) to form guanosine diphosphate (GDP).".
- Small_GTPase label "Small GTPase".
- Small_GTPase sameAs Kleine_GTPase.
- Small_GTPase sameAs Petite_GTPase.
- Small_GTPase sameAs GTPase_pequena.
- Small_GTPase sameAs 低分子量GTPアーゼ.
- Small_GTPase sameAs m.0238mv.
- Small_GTPase sameAs Mala_GTPaza.
- Small_GTPase sameAs Male_GTPaze.
- Small_GTPase sameAs Q415071.
- Small_GTPase sameAs Q415071.
- Small_GTPase wasDerivedFrom Small_GTPase?oldid=667697457.
- Small_GTPase isPrimaryTopicOf Small_GTPase.
- Small_GTPase name "Small monomeric GTPase".