Matches in DBpedia 2015-10 for { <http://dbpedia.org/resource/Sialyltransferase> ?p ?o }
Showing triples 1 to 77 of
77
with 100 triples per page.
- Sialyltransferase abstract "Sialyltransferases are enzymes that transfer sialic acid to nascent oligosaccharide.Each sialyltransferase is specific for a particular sugar substrate. Sialyltransferases add sialic acid to the terminal portions of the sialylated glycolipids (gangliosides) or to the N- or O-linked sugar chains of glycoproteins. The biosynthesis of disaccharides, oligosaccharides and polysaccharides involves the action of hundreds of different glycosyltransferases. These enzymes catalyse the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. A classification of glycosyltransferases using nucleotide diphospho-sugar, nucleotide monophospho-sugar and sugar phosphates (EC 2.4.1.-) and related proteins into distinct sequence based families has been described. This classification is available on the CAZy (CArbohydrate-Active EnZymes) web site. The same three-dimensional fold is expected to occur within each of the families. Because 3-D structures are better conserved than sequences, several of the families defined on the basis of sequence similarities may have similar 3-D structures and therefore form 'clans'.Sialyltransferases belong to glycosyltransferase family 29 (CAZY GT_29) which comprises enzymes with a number of known activities; sialyltransferase (EC 2.4.99), beta-galactosamide alpha-2,6-sialyltransferase (EC 2.4.99.1), alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase (EC 2.4.99.3), beta-galactoside alpha-2,3-sialyltransferase (EC 2.4.99.4), N-acetyllactosaminide alpha-2,3-sialyltransferase (EC 2.4.99.6), alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase (EC 2.4.99.8); lactosylceramide alpha-2,3-sialyltransferase (EC 2.4.99.9). These enzymes use a nucleotide monophosphosugar as the donor (CMP-NeuA) instead of a nucleotide diphosphosugar. Sialyltransferase may be responsible for the synthesis of the sequence NEUAC-Alpha-2,3-GAL-Beta-1,3-GALNAC-, found on sugar chains O-linked to thr or ser and also as a terminal sequenec on certain gagnliosides. These enzymes catalyse sialyltransfer reactions during glycosylation, and are type II membrane proteins.There are about twenty different sialyltransferases which can be distinguished on the basis of the acceptor structure on which they act and on the type of sugar linkage they form. For example, a group of sialyltransferases adds sialic acid with an alpha-2,3 linkage to galactose, while other sialyltransferases add sialic acid with an alpha-2,6 linkage to galactose or N-acetylgalactosamine. A peculiar type of sialyltransferases add sialic acid to other sialic acid units with an alpha-2,8 linkage, forming structures referred to as polysialic acid. As occurs for other glycosyltransferases, the expression of sialyltransferases undergoes profound modifications during cell differentiation and neoplastic transformation; in some cases such changes induce phenotypic alterations.".
- Sialyltransferase symbol "Glyco_transf_29".
- Sialyltransferase wikiPageExternalLink GT_29.html.
- Sialyltransferase wikiPageID "6237655".
- Sialyltransferase wikiPageLength "4740".
- Sialyltransferase wikiPageOutDegree "35".
- Sialyltransferase wikiPageRevisionID "486295997".
- Sialyltransferase wikiPageWikiLink Carcinogenesis.
- Sialyltransferase wikiPageWikiLink Category:EC_2.4.
- Sialyltransferase wikiPageWikiLink Category:Transferases.
- Sialyltransferase wikiPageWikiLink Cell_differentiation.
- Sialyltransferase wikiPageWikiLink Cellular_differentiation.
- Sialyltransferase wikiPageWikiLink Enzyme.
- Sialyltransferase wikiPageWikiLink Galactose.
- Sialyltransferase wikiPageWikiLink Ganglioside.
- Sialyltransferase wikiPageWikiLink Glycolipid.
- Sialyltransferase wikiPageWikiLink Glycoprotein.
- Sialyltransferase wikiPageWikiLink Glycosyltransferase.
- Sialyltransferase wikiPageWikiLink N-Acetylgalactosamine.
- Sialyltransferase wikiPageWikiLink Oligosaccharide.
- Sialyltransferase wikiPageWikiLink Phenotype.
- Sialyltransferase wikiPageWikiLink Polysialic_acid.
- Sialyltransferase wikiPageWikiLink SIAT4C.
- Sialyltransferase wikiPageWikiLink SIAT9.
- Sialyltransferase wikiPageWikiLink ST3GAL1.
- Sialyltransferase wikiPageWikiLink ST3GAL2.
- Sialyltransferase wikiPageWikiLink ST3GAL3.
- Sialyltransferase wikiPageWikiLink ST3GAL4.
- Sialyltransferase wikiPageWikiLink ST3GAL5.
- Sialyltransferase wikiPageWikiLink ST3GAL6.
- Sialyltransferase wikiPageWikiLink ST3GalIII.
- Sialyltransferase wikiPageWikiLink ST6GAL1.
- Sialyltransferase wikiPageWikiLink ST6GAL2.
- Sialyltransferase wikiPageWikiLink ST6Gal.
- Sialyltransferase wikiPageWikiLink ST8SIA1.
- Sialyltransferase wikiPageWikiLink ST8SIA2.
- Sialyltransferase wikiPageWikiLink ST8SIA3.
- Sialyltransferase wikiPageWikiLink ST8SIA4.
- Sialyltransferase wikiPageWikiLink ST8SIA5.
- Sialyltransferase wikiPageWikiLink ST8SIA6.
- Sialyltransferase wikiPageWikiLink ST8Sia.
- Sialyltransferase wikiPageWikiLink Sialic_acid.
- Sialyltransferase wikiPageWikiLink Sugar.
- Sialyltransferase wikiPageWikiLink Tumorigenesis.
- Sialyltransferase wikiPageWikiLinkText "Sialyltransferase".
- Sialyltransferase wikiPageWikiLinkText "sialyltransferase".
- Sialyltransferase hasPhotoCollection Sialyltransferase.
- Sialyltransferase interpro "IPR001675".
- Sialyltransferase name "Glycosyltransferase family 29".
- Sialyltransferase pfam "PF00777".
- Sialyltransferase symbol "Glyco_transf_29".
- Sialyltransferase wikiPageUsesTemplate Template:Context.
- Sialyltransferase wikiPageUsesTemplate Template:EC_number.
- Sialyltransferase wikiPageUsesTemplate Template:Glycosyltransferases.
- Sialyltransferase wikiPageUsesTemplate Template:InterPro_content.
- Sialyltransferase wikiPageUsesTemplate Template:MeshName.
- Sialyltransferase wikiPageUsesTemplate Template:Pfam_box.
- Sialyltransferase wikiPageUsesTemplate Template:Reflist.
- Sialyltransferase wikiPageUsesTemplate Template:Transferase-stub.
- Sialyltransferase subject Category:EC_2.4.
- Sialyltransferase subject Category:Transferases.
- Sialyltransferase hypernym Enzymes.
- Sialyltransferase type Article.
- Sialyltransferase type Biomolecule.
- Sialyltransferase type Protein.
- Sialyltransferase type Article.
- Sialyltransferase type Page.
- Sialyltransferase type Thing.
- Sialyltransferase type Q206229.
- Sialyltransferase type Q8054.
- Sialyltransferase comment "Sialyltransferases are enzymes that transfer sialic acid to nascent oligosaccharide.Each sialyltransferase is specific for a particular sugar substrate. Sialyltransferases add sialic acid to the terminal portions of the sialylated glycolipids (gangliosides) or to the N- or O-linked sugar chains of glycoproteins. The biosynthesis of disaccharides, oligosaccharides and polysaccharides involves the action of hundreds of different glycosyltransferases.".
- Sialyltransferase label "Sialyltransferase".
- Sialyltransferase sameAs m.0fy976.
- Sialyltransferase sameAs Q7506698.
- Sialyltransferase sameAs Q7506698.
- Sialyltransferase wasDerivedFrom Sialyltransferase?oldid=486295997.
- Sialyltransferase isPrimaryTopicOf Sialyltransferase.