Matches in DBpedia 2015-10 for { <http://dbpedia.org/resource/Seletracetam> ?p ?o }
- Seletracetam abstract "Seletracetam (UCB 44212) is a pyrrolidone-derived drug of the racetam family that is structurally related to levetiracetam (trade name Keppra). It was under development by UCB Pharmaceuticals as a more potent and effective anticonvulsant drug to replace levetiracetam but its production has been halted.There are two main mechanisms of action for seletracetam. The first is its high-affinity stereospecific binding to synaptic vesicle glycoprotein 2A (SV2A). Seletracetam has shown potent seizure suppression in models of acquired and genetic epilepsy, and has been well tolerated by various animal models. The second is its binding to N-type calcium channels and preventing influx of Ca2+ during high-voltage activation that is typical of epilepsy.While similar in structure to nootropic drugs, it is not expected to have cognitive enhancing properties. Seletracetam was in Phase II clinical trials under the supervision of the U.S. Food and Drug Administration (FDA) but its production is on hold.".
- Seletracetam atcPrefix "none".
- Seletracetam casNumber "357336-74-4".
- Seletracetam fdaUniiCode "RFR2CH3QZK".
- Seletracetam iupacName "(2S)-2-[(4R)-4-(2,2-difluoroethenyl)-2-oxo-pyrrolidin-1-yl]butanamide".
- Seletracetam pubchem "9856063".
- Seletracetam thumbnail Seletracetam.svg?width=300.
- Seletracetam wikiPageID "12407585".
- Seletracetam wikiPageLength "21769".
- Seletracetam wikiPageOutDegree "89".
- Seletracetam wikiPageRevisionID "671865002".
- Seletracetam wikiPageWikiLink 2-Pyrrolidone.
- Seletracetam wikiPageWikiLink 2-pyrrolidone.
- Seletracetam wikiPageWikiLink AMPA.
- Seletracetam wikiPageWikiLink Absence_epilepsy.
- Seletracetam wikiPageWikiLink Absence_seizure.
- Seletracetam wikiPageWikiLink Acetamide.
- Seletracetam wikiPageWikiLink Action_potential.
- Seletracetam wikiPageWikiLink Amplitude.
- Seletracetam wikiPageWikiLink Animal_models.
- Seletracetam wikiPageWikiLink Anticonvulsant.
- Seletracetam wikiPageWikiLink Anticonvulsants.
- Seletracetam wikiPageWikiLink Bioavailability.
- Seletracetam wikiPageWikiLink Biological_half-life.
- Seletracetam wikiPageWikiLink Brivaracetam.
- Seletracetam wikiPageWikiLink Calcium_in_biology.
- Seletracetam wikiPageWikiLink Carbamazepine.
- Seletracetam wikiPageWikiLink Carboxylic_acid.
- Seletracetam wikiPageWikiLink Category:Alkenes.
- Seletracetam wikiPageWikiLink Category:Butyramides.
- Seletracetam wikiPageWikiLink Category:Organofluorides.
- Seletracetam wikiPageWikiLink Category:Pyrrolidones.
- Seletracetam wikiPageWikiLink Category:Racetams.
- Seletracetam wikiPageWikiLink Central_nervous_system.
- Seletracetam wikiPageWikiLink Clinical_trial.
- Seletracetam wikiPageWikiLink Clinical_trials.
- Seletracetam wikiPageWikiLink Clonic_seizures.
- Seletracetam wikiPageWikiLink Clonus.
- Seletracetam wikiPageWikiLink Drug.
- Seletracetam wikiPageWikiLink Effective_dose_(pharmacology).
- Seletracetam wikiPageWikiLink Electronegative.
- Seletracetam wikiPageWikiLink Electronegativity.
- Seletracetam wikiPageWikiLink Epilepsy.
- Seletracetam wikiPageWikiLink Epileptic.
- Seletracetam wikiPageWikiLink Extracellular_fluid.
- Seletracetam wikiPageWikiLink Food_and_Drug_Administration.
- Seletracetam wikiPageWikiLink Functional_group.
- Seletracetam wikiPageWikiLink GABA.
- Seletracetam wikiPageWikiLink Gamma-Aminobutyric_acid.
- Seletracetam wikiPageWikiLink Glycine.
- Seletracetam wikiPageWikiLink Imide.
- Seletracetam wikiPageWikiLink Intraperitoneal_injection.
- Seletracetam wikiPageWikiLink Kainic_acid.
- Seletracetam wikiPageWikiLink Kindling_model.
- Seletracetam wikiPageWikiLink Levetiracetam.
- Seletracetam wikiPageWikiLink Model_organism.
- Seletracetam wikiPageWikiLink N-Methyl-D-aspartic_acid.
- Seletracetam wikiPageWikiLink N-type_calcium_channel.
- Seletracetam wikiPageWikiLink NMDA.
- Seletracetam wikiPageWikiLink Neuron.
- Seletracetam wikiPageWikiLink Neurotransmitter.
- Seletracetam wikiPageWikiLink Nootropic.
- Seletracetam wikiPageWikiLink Order_of_reaction.
- Seletracetam wikiPageWikiLink Pentylenetetrazol.
- Seletracetam wikiPageWikiLink Pharmacokinetics.
- Seletracetam wikiPageWikiLink Phenobarbital.
- Seletracetam wikiPageWikiLink Population_spike.
- Seletracetam wikiPageWikiLink Potassium.
- Seletracetam wikiPageWikiLink Racetam.
- Seletracetam wikiPageWikiLink Rotarod.
- Seletracetam wikiPageWikiLink Rotarod_performance_test.
- Seletracetam wikiPageWikiLink SV2A.
- Seletracetam wikiPageWikiLink Sodium.
- Seletracetam wikiPageWikiLink Sodium_channel.
- Seletracetam wikiPageWikiLink Somnolence.
- Seletracetam wikiPageWikiLink Stereospecificity.
- Seletracetam wikiPageWikiLink T-type_calcium_channel.
- Seletracetam wikiPageWikiLink Toxicology.
- Seletracetam wikiPageWikiLink Valproate.
- Seletracetam wikiPageWikiLink Voltage-gated_sodium_channel.
- Seletracetam wikiPageWikiLinkText "Seletracetam".
- Seletracetam wikiPageWikiLinkText "seletracetam".
- Seletracetam atcPrefix "none".
- Seletracetam c "10".
- Seletracetam casNumber "357336".
- Seletracetam chemspiderid "8031763".
- Seletracetam eliminationHalfLife "28800.0".
- Seletracetam f "2".
- Seletracetam h "14".
- Seletracetam hasPhotoCollection Seletracetam.
- Seletracetam image "Selectracetam3d.png".
- Seletracetam inchi "1".
- Seletracetam inchikey "ANWPENAPCIFDSZ-BQBZGAKWBQ".
- Seletracetam iupacName "-2".
- Seletracetam kegg "D05817".
- Seletracetam legalStatus "Unscheduled".
- Seletracetam molecularWeight "232.227".
- Seletracetam n "2".
- Seletracetam o "1".
- Seletracetam pubchem "9856063".
