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- STAU1 abstract "Double-stranded RNA-binding protein Staufen homolog 1 is a protein that in humans is encoded by the STAU1 gene.Staufen is a member of the family of double-stranded RNA (dsRNA)-binding proteins involved in the transport and/or localization of mRNAs to different subcellular compartments and/or organelles. These proteins are characterized by the presence of multiple dsRNA-binding domains which are required to bind RNAs having double-stranded secondary structures. The human homologue of staufen encoded by STAU, in addition contains a microtubule-binding domain similar to that of microtubule-associated protein 1B, and binds tubulin. The STAU gene product has been shown to be present in the cytoplasm in association with the rough endoplasmic reticulum (RER), implicating this protein in the transport of mRNA via the microtubule network to the RER, the site of translation. Five transcript variants resulting from alternative splicing of STAU gene and encoding three isoforms have been described. Three of these variants encode the same isoform, however, differ in their 5'UTR.".
- STAU1 entrezgene "6780".
- STAU1 wikiPageID "14774786".
- STAU1 wikiPageLength "8372".
- STAU1 wikiPageOutDegree "5".
- STAU1 wikiPageRevisionID "679041762".
- STAU1 wikiPageWikiLink Endoplasmic_reticulum.
- STAU1 wikiPageWikiLink Gene.
- STAU1 wikiPageWikiLink Messenger_RNA.
- STAU1 wikiPageWikiLink Protein.
- STAU1 wikiPageWikiLink RNA.
- STAU1 wikiPageWikiLink Rough_endoplasmic_reticulum.
- STAU1 wikiPageWikiLinkText "STAU1".
- STAU1 hasPhotoCollection STAU1.
- STAU1 requireManualInspection "no".
- STAU1 summaryText "Staufen is a member of the family of double-stranded RNA -binding proteins involved in the transport and/or localization of mRNAs to different subcellular compartments and/or organelles. These proteins are characterized by the presence of multiple dsRNA-binding domains which are required to bind RNAs having double-stranded secondary structures. The human homologue of staufen encoded by STAU, in addition contains a microtubule-binding domain similar to that of microtubule-associated protein 1B, and binds tubulin. The STAU gene product has been shown to be present in the cytoplasm in association with the rough endoplasmic reticulum , implicating this protein in the transport of mRNA via the microtubule network to the RER, the site of translation. Five transcript variants resulting from alternative splicing of STAU gene and encoding three isoforms have been described. Three of these variants encode the same isoform, however, differ in their 5'UTR.".
- STAU1 updateCitations "yes".
- STAU1 updatePage "yes".
- STAU1 updateProteinBox "yes".
- STAU1 updateSummary "yes".
- STAU1 wikiPageUsesTemplate Template:Gene-20-stub.
- STAU1 wikiPageUsesTemplate Template:Multiple_issues.
- STAU1 wikiPageUsesTemplate Template:PBB.
- STAU1 wikiPageUsesTemplate Template:PBB_Controls.
- STAU1 wikiPageUsesTemplate Template:PBB_Further_reading.
- STAU1 wikiPageUsesTemplate Template:PBB_Summary.
- STAU1 wikiPageUsesTemplate Template:Refbegin.
- STAU1 wikiPageUsesTemplate Template:Refend.
- STAU1 wikiPageUsesTemplate Template:Reflist.
- STAU1 hypernym Protein.
- STAU1 type Article.
- STAU1 type Biomolecule.
- STAU1 type Protein.
- STAU1 type Article.
- STAU1 type Thing.
- STAU1 type Q206229.
- STAU1 type Q8054.
- STAU1 comment "Double-stranded RNA-binding protein Staufen homolog 1 is a protein that in humans is encoded by the STAU1 gene.Staufen is a member of the family of double-stranded RNA (dsRNA)-binding proteins involved in the transport and/or localization of mRNAs to different subcellular compartments and/or organelles. These proteins are characterized by the presence of multiple dsRNA-binding domains which are required to bind RNAs having double-stranded secondary structures.".
- STAU1 label "STAU1".
- STAU1 sameAs m.03gxlg8.
- STAU1 sameAs Q7394695.
- STAU1 sameAs Q7394695.
- STAU1 wasDerivedFrom STAU1?oldid=679041762.
- STAU1 isPrimaryTopicOf STAU1.