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- Ryanodine abstract "Ryanodine is a poisonous alkaloid found in the South American plant Ryania speciosa (Salicaceae). It was originally used as an insecticide.The compound has extremely high affinity to the open-form ryanodine receptor, a group of calcium channels found in skeletal muscle, smooth muscle, and heart muscle cells. It binds with such high affinity to the receptor that it was used as a label for the first purification of that class of ion channels and gave its name to it.At nanomolar concentrations, ryanodine locks the receptor in a half-open state, whereas it fully closes them at micromolar concentration. The effect of the nanomolar-level binding is that ryanodine causes release of calcium from calcium stores as the sarcoplasmic reticulum in the cytoplasm, leading to massive muscular contractions. The effect of micromolar-level binding is paralysis. This is true for both mammals and insects.".
- Ryanodine thumbnail Ryanodine_structure.png?width=300.
- Ryanodine wikiPageID "7365444".
- Ryanodine wikiPageLength "3022".
- Ryanodine wikiPageOutDegree "22".
- Ryanodine wikiPageRevisionID "668739197".
- Ryanodine wikiPageWikiLink Alkaloid.
- Ryanodine wikiPageWikiLink Bertil_Hille.
- Ryanodine wikiPageWikiLink Calcium.
- Ryanodine wikiPageWikiLink Calcium_channel.
- Ryanodine wikiPageWikiLink Cardiac_muscle.
- Ryanodine wikiPageWikiLink Category:Alcohols.
- Ryanodine wikiPageWikiLink Category:Alkaloids.
- Ryanodine wikiPageWikiLink Category:Carboxylate_esters.
- Ryanodine wikiPageWikiLink Category:Insecticides.
- Ryanodine wikiPageWikiLink Category:Pyrroles.
- Ryanodine wikiPageWikiLink Endoplasmic_reticulum.
- Ryanodine wikiPageWikiLink Heart_muscle.
- Ryanodine wikiPageWikiLink Inotrope.
- Ryanodine wikiPageWikiLink Inotropic.
- Ryanodine wikiPageWikiLink Insecticide.
- Ryanodine wikiPageWikiLink Ion_channel.
- Ryanodine wikiPageWikiLink Micromolar.
- Ryanodine wikiPageWikiLink Molar_concentration.
- Ryanodine wikiPageWikiLink Nanomolar.
- Ryanodine wikiPageWikiLink Paralysis.
- Ryanodine wikiPageWikiLink Ryania_speciosa.
- Ryanodine wikiPageWikiLink Ryanodine_receptor.
- Ryanodine wikiPageWikiLink Ryanoid.
- Ryanodine wikiPageWikiLink Salicaceae.
- Ryanodine wikiPageWikiLink Sarcoplasmic_reticulum.
- Ryanodine wikiPageWikiLink Striated_muscle.
- Ryanodine wikiPageWikiLink Striated_muscle_tissue.
- Ryanodine wikiPageWikiLinkText "RyR".
- Ryanodine wikiPageWikiLinkText "Ryanodine".
- Ryanodine wikiPageWikiLinkText "ryanodine".
- Ryanodine hasPhotoCollection Ryanodine.
- Ryanodine imagefile "Ryanodine_structure.png".
- Ryanodine imagesize "240".
- Ryanodine verifiedfields "changed".
- Ryanodine verifiedrevid "464384841".
- Ryanodine wikiPageUsesTemplate Template:Chembox.
- Ryanodine wikiPageUsesTemplate Template:Insecticides.
- Ryanodine subject Category:Alcohols.
- Ryanodine subject Category:Alkaloids.
- Ryanodine subject Category:Carboxylate_esters.
- Ryanodine subject Category:Insecticides.
- Ryanodine subject Category:Pyrroles.
- Ryanodine hypernym Alkaloid.
- Ryanodine type Biomolecule.
- Ryanodine type ChemicalCompound.
- Ryanodine type ChemicalSubstance.
- Ryanodine type Alcohol.
- Ryanodine type Alkaloid.
- Ryanodine type Azole.
- Ryanodine type Biomolecule.
- Ryanodine type Chemical.
- Ryanodine type Ester.
- Ryanodine type Insecticide.
- Ryanodine type Pesticide.
- Ryanodine type Insecticide.
- Ryanodine type ChemicalObject.
- Ryanodine type Thing.
- Ryanodine type Q11173.
- Ryanodine comment "Ryanodine is a poisonous alkaloid found in the South American plant Ryania speciosa (Salicaceae). It was originally used as an insecticide.The compound has extremely high affinity to the open-form ryanodine receptor, a group of calcium channels found in skeletal muscle, smooth muscle, and heart muscle cells.".
- Ryanodine label "Ryanodine".
- Ryanodine sameAs Ryanodin.
- Ryanodine sameAs ریانودین.
- Ryanodine sameAs Ryanodine.
- Ryanodine sameAs Rianodin.
- Ryanodine sameAs Rianodina.
- Ryanodine sameAs リアノジン.
- Ryanodine sameAs Ryanodine.
- Ryanodine sameAs Rianodyna.
- Ryanodine sameAs m.025_g34.
- Ryanodine sameAs Rijanodin.
- Ryanodine sameAs Rijanodin.
- Ryanodine sameAs Ryanodin.
- Ryanodine sameAs Q424726.
- Ryanodine sameAs Q424726.
- Ryanodine wasDerivedFrom Ryanodine?oldid=668739197.
- Ryanodine depiction Ryanodine_structure.png.
- Ryanodine isPrimaryTopicOf Ryanodine.