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- Ruthenium_red abstract "The inorganic dye ammoniated ruthenium oxychloride, also known as ruthenium red, is used in histology to stain aldehyde fixed mucopolysaccharides.Ruthenium red (RR) has also been used as a pharmacological tool to study specific cellular mechanisms. Selectivity is a significant issue in such studies as RR is known to interact with a large number of proteins. These include mammalian ion channels (CatSper1, TASK, RyR1, RyR2, RyR3, TRPM6, TRPM8, TRPV1, TRPV2, TRPV3, TRPV4, TRPV5, TRPV6, TRPA1, mCa1, mCa2, CALHM1) TRPP3, a plant ion channel, Ca2+-ATPase, mitochondrial Ca2+ uniporter, tubulin, myosin light-chain phosphatase, and Ca2+ binding proteins such as calmodulin. It should be further noted that ruthenium red displays nanomolar potency against several of its binding partners (e.g. TRPV4, ryanodine receptors,...). For example, it is a potent inhibitor of intracellular calcium release by ryanodine receptors (Kd ~20 nM). As a TRPA1 blocker, it assists in reducing the airway inflammation caused by pepper spray.RR has been used on plant material since 1890 for staining pectins, mucilages, and gums. RR is a stereoselective stain for pectic acid, insofar as the staining site occurs between each monomer unit and the next adjacent neighbor.".
- Ruthenium_red thumbnail Ruthenium_red_cation.svg?width=300.
- Ruthenium_red wikiPageID "7557398".
- Ruthenium_red wikiPageLength "4584".
- Ruthenium_red wikiPageOutDegree "36".
- Ruthenium_red wikiPageRevisionID "678184093".
- Ruthenium_red wikiPageWikiLink (myosin-light-chain)_phosphatase.
- Ruthenium_red wikiPageWikiLink Aldehyde.
- Ruthenium_red wikiPageWikiLink CALHM1.
- Ruthenium_red wikiPageWikiLink Calcium.
- Ruthenium_red wikiPageWikiLink Calcium_ATPase.
- Ruthenium_red wikiPageWikiLink Calmodulin.
- Ruthenium_red wikiPageWikiLink CatSper1.
- Ruthenium_red wikiPageWikiLink Category:Ruthenium_compounds.
- Ruthenium_red wikiPageWikiLink Category:Staining_dyes.
- Ruthenium_red wikiPageWikiLink Fixation_(histology).
- Ruthenium_red wikiPageWikiLink Glycosaminoglycan.
- Ruthenium_red wikiPageWikiLink Histology.
- Ruthenium_red wikiPageWikiLink MCa1.
- Ruthenium_red wikiPageWikiLink MCa2.
- Ruthenium_red wikiPageWikiLink Mucilage.
- Ruthenium_red wikiPageWikiLink Mucopolysaccharides.
- Ruthenium_red wikiPageWikiLink Myosin_light-chain_phosphatase.
- Ruthenium_red wikiPageWikiLink Natural_gum.
- Ruthenium_red wikiPageWikiLink Pectin.
- Ruthenium_red wikiPageWikiLink Pectins.
- Ruthenium_red wikiPageWikiLink Pepper_spray.
- Ruthenium_red wikiPageWikiLink RyR1.
- Ruthenium_red wikiPageWikiLink RyR2.
- Ruthenium_red wikiPageWikiLink RyR3.
- Ruthenium_red wikiPageWikiLink Ryanodine.
- Ruthenium_red wikiPageWikiLink Ryanodine_receptor.
- Ruthenium_red wikiPageWikiLink Ryanodine_receptor_2.
- Ruthenium_red wikiPageWikiLink Staining.
- Ruthenium_red wikiPageWikiLink TASK.
- Ruthenium_red wikiPageWikiLink TRPA1.
- Ruthenium_red wikiPageWikiLink TRPM6.
- Ruthenium_red wikiPageWikiLink TRPM8.
- Ruthenium_red wikiPageWikiLink TRPP3.
- Ruthenium_red wikiPageWikiLink TRPV1.
- Ruthenium_red wikiPageWikiLink TRPV2.
- Ruthenium_red wikiPageWikiLink TRPV3.
- Ruthenium_red wikiPageWikiLink TRPV4.
- Ruthenium_red wikiPageWikiLink TRPV5.
- Ruthenium_red wikiPageWikiLink TRPV6.
- Ruthenium_red wikiPageWikiLink Tandem_pore_domain_potassium_channel.
- Ruthenium_red wikiPageWikiLink Transient_receptor_potential_cation_channel,_member_A1.
- Ruthenium_red wikiPageWikiLink Tubulin.
- Ruthenium_red wikiPageWikiLink Uniporter.
- Ruthenium_red wikiPageWikiLinkText "Ruthenium red".
- Ruthenium_red wikiPageWikiLinkText "ammoniated ruthenium oxychloride".
- Ruthenium_red wikiPageWikiLinkText "ruthenium red".
- Ruthenium_red hasPhotoCollection Ruthenium_red.
- Ruthenium_red imagefile "Ruthenium red cation.svg".
- Ruthenium_red name "Ammoniated ruthenium oxychloride".
- Ruthenium_red verifiedfields "changed".
- Ruthenium_red verifiedrevid "464384628".
- Ruthenium_red wikiPageUsesTemplate Template:Chembox.
- Ruthenium_red subject Category:Ruthenium_compounds.
- Ruthenium_red subject Category:Staining_dyes.
- Ruthenium_red type ChemicalCompound.
- Ruthenium_red type ChemicalSubstance.
- Ruthenium_red type Chemical.
- Ruthenium_red type ChemicalObject.
- Ruthenium_red type Thing.
- Ruthenium_red type Q11173.
- Ruthenium_red comment "The inorganic dye ammoniated ruthenium oxychloride, also known as ruthenium red, is used in histology to stain aldehyde fixed mucopolysaccharides.Ruthenium red (RR) has also been used as a pharmacological tool to study specific cellular mechanisms. Selectivity is a significant issue in such studies as RR is known to interact with a large number of proteins.".
- Ruthenium_red label "Ruthenium red".
- Ruthenium_red sameAs Rutheniumrot.
- Ruthenium_red sameAs Rosso_di_Rutenio.
- Ruthenium_red sameAs m.02658kq.
- Ruthenium_red sameAs Rutenijum_red.
- Ruthenium_red sameAs Rutenijum_red.
- Ruthenium_red sameAs Q424006.
- Ruthenium_red sameAs Q424006.
- Ruthenium_red wasDerivedFrom Ruthenium_red?oldid=678184093.
- Ruthenium_red depiction Ruthenium_red_cation.svg.
- Ruthenium_red isPrimaryTopicOf Ruthenium_red.
- Ruthenium_red name "Ammoniated ruthenium oxychloride".