Matches in DBpedia 2015-10 for { <http://dbpedia.org/resource/Robert_W._Holley> ?p ?o }
- Robert_W._Holley abstract "Robert William Holley (January 28, 1922 – February 11, 1993) was an American biochemist. He shared the Nobel Prize in Physiology or Medicine in 1968 (with Har Gobind Khorana and Marshall Warren Nirenberg) for describing the structure of alanine transfer RNA, linking DNA and protein synthesis.Holley was born in Urbana, Illinois, and graduated from Urbana High School in 1938. He went on to study chemistry at the University of Illinois at Urbana-Champaign, graduating in 1942 and commencing his PhD studies in organic chemistry at Cornell University. During World War II Holley spent two years working under Professor Vincent du Vigneaud at Cornell University Medical College, where he was involved in the first chemical synthesis of penicillin. Holley completed his PhD studies in 1947.*USDA ARS.Following his graduate studies Holley remained associated with Cornell. He became an Assistant Professor of organic chemistry in 1948, and was appointed as Professor of Biochemistry in 1962. He began his research on RNA after spending a year's sabbatical (1955–1956) studying with James F. Bonner at the California Institute of Technology.Holley's research on RNA focused first on isolating transfer RNA (tRNA), and later on determining the sequence and structure of alanine tRNA, the molecule that incorporates the amino acid alanine into proteins. Holley's team of researchers determined the tRNA's structure by using two ribonucleases to split the tRNA molecule into pieces. Each enzyme split the molecule at location points for specific nucleotides. By a process of "puzzling out" the structure of the pieces split by the two different enzymes, then comparing the pieces from both enzyme splits, the team eventually determined the entire structure of the molecule.The structure was completed in 1964, and was a key discovery in explaining the synthesis of proteins from messenger RNA. It was also the first nucleotide sequence of a ribonucleic acid ever determined. Holley was awarded the Nobel Prize in Physiology or Medicine in 1968 for this discovery, and Har Gobind Khorana and Marshall W. Nirenberg were also awarded the prize that year for contributions to the understanding of protein synthesis.Using the Holley team's method, other scientists determined the structures of the remaining tRNA's. A few years later the method was modified to help track the sequence of nucleotides in various bacterial, plant, and human viruses.In 1968 Holley became a resident fellow at the Salk Institute for Biological Studies in La Jolla, California.Holley was married to Ann Dworkin (1925-1996).".
- Robert_W._Holley almaMater Cornell_University.
- Robert_W._Holley almaMater University_of_Illinois_at_Urbana–Champaign.
- Robert_W._Holley birthDate "1922-01-28".
- Robert_W._Holley birthPlace Urbana,_Illinois.
- Robert_W._Holley birthYear "1922".
- Robert_W._Holley deathDate "1993-02-11".
- Robert_W._Holley deathPlace Los_Gatos,_California.
- Robert_W._Holley deathYear "1993".
- Robert_W._Holley field Biochemistry.
- Robert_W._Holley knownFor Transfer_RNA.
- Robert_W._Holley thumbnail Robert_W._Holley_nobel.jpg?width=300.
- Robert_W._Holley wikiPageID "1508474".
- Robert_W._Holley wikiPageLength "6060".
- Robert_W._Holley wikiPageOutDegree "59".
- Robert_W._Holley wikiPageRevisionID "660547027".
- Robert_W._Holley wikiPageWikiLink Alanine.
- Robert_W._Holley wikiPageWikiLink Albert_Lasker_Award_for_Basic_Medical_Research.
- Robert_W._Holley wikiPageWikiLink Amino_acid.
- Robert_W._Holley wikiPageWikiLink Biochemist.
- Robert_W._Holley wikiPageWikiLink Biochemistry.
- Robert_W._Holley wikiPageWikiLink California_Institute_of_Technology.
- Robert_W._Holley wikiPageWikiLink Category:1922_births.
- Robert_W._Holley wikiPageWikiLink Category:1993_deaths.
- Robert_W._Holley wikiPageWikiLink Category:American_Nobel_laureates.
- Robert_W._Holley wikiPageWikiLink Category:American_biochemists.
- Robert_W._Holley wikiPageWikiLink Category:Guggenheim_Fellows.
- Robert_W._Holley wikiPageWikiLink Category:Nobel_laureates_in_Physiology_or_Medicine.
- Robert_W._Holley wikiPageWikiLink Category:People_from_Urbana,_Illinois.
- Robert_W._Holley wikiPageWikiLink Category:Recipients_of_the_Albert_Lasker_Award_for_Basic_Medical_Research.
- Robert_W._Holley wikiPageWikiLink Category:University_of_Illinois_at_Urbana–Champaign_alumni.
- Robert_W._Holley wikiPageWikiLink Category:Weill_Cornell_Medical_College_alumni.
- Robert_W._Holley wikiPageWikiLink Chemistry.
- Robert_W._Holley wikiPageWikiLink Cornell_University.
- Robert_W._Holley wikiPageWikiLink DNA.
- Robert_W._Holley wikiPageWikiLink Doctor_of_Philosophy.
- Robert_W._Holley wikiPageWikiLink Har_Gobind_Khorana.
- Robert_W._Holley wikiPageWikiLink History_of_RNA_biology.
- Robert_W._Holley wikiPageWikiLink James_F._Bonner.
- Robert_W._Holley wikiPageWikiLink La_Jolla.
- Robert_W._Holley wikiPageWikiLink La_Jolla,_California.
- Robert_W._Holley wikiPageWikiLink List_of_RNA_biologists.
- Robert_W._Holley wikiPageWikiLink Los_Gatos,_California.
- Robert_W._Holley wikiPageWikiLink MRNA.
- Robert_W._Holley wikiPageWikiLink Marshall_W._Nirenberg.
- Robert_W._Holley wikiPageWikiLink Marshall_Warren_Nirenberg.
- Robert_W._Holley wikiPageWikiLink Messenger_RNA.
- Robert_W._Holley wikiPageWikiLink NAS_Award_in_Molecular_Biology.
- Robert_W._Holley wikiPageWikiLink Nobel_Prize_in_Physiology_or_Medicine.
- Robert_W._Holley wikiPageWikiLink Organic_chemistry.
- Robert_W._Holley wikiPageWikiLink Penicillin.
- Robert_W._Holley wikiPageWikiLink PhD.
- Robert_W._Holley wikiPageWikiLink Protein.
- Robert_W._Holley wikiPageWikiLink Protein_synthesis.
- Robert_W._Holley wikiPageWikiLink RNA.
- Robert_W._Holley wikiPageWikiLink Ribonuclease.
- Robert_W._Holley wikiPageWikiLink Ribonucleic_acid.
- Robert_W._Holley wikiPageWikiLink Salk_Institute.
- Robert_W._Holley wikiPageWikiLink Salk_Institute_for_Biological_Studies.
- Robert_W._Holley wikiPageWikiLink TRNA.
- Robert_W._Holley wikiPageWikiLink Transfer_RNA.
- Robert_W._Holley wikiPageWikiLink Translation_(biology).
- Robert_W._Holley wikiPageWikiLink Translation_(genetics).
- Robert_W._Holley wikiPageWikiLink University_of_Illinois_at_Urbana-Champaign.
- Robert_W._Holley wikiPageWikiLink University_of_Illinois_at_Urbana–Champaign.
- Robert_W._Holley wikiPageWikiLink Urbana,_Illinois.
- Robert_W._Holley wikiPageWikiLink Vincent_du_Vigneaud.
- Robert_W._Holley wikiPageWikiLink Virus.
- Robert_W._Holley wikiPageWikiLink World_War_II.
- Robert_W._Holley wikiPageWikiLink File:R_Holley.jpg.
- Robert_W._Holley wikiPageWikiLinkText "Holley, Robert William".
- Robert_W._Holley wikiPageWikiLinkText "Holley, Robert".
- Robert_W._Holley wikiPageWikiLinkText "Robert Holley".
- Robert_W._Holley wikiPageWikiLinkText "Robert W. Holley".
- Robert_W._Holley almaMater Cornell_University.
- Robert_W._Holley almaMater University_of_Illinois_at_Urbana–Champaign.
- Robert_W._Holley birthDate "1922-01-28".
- Robert_W._Holley birthPlace Urbana,_Illinois.
- Robert_W._Holley dateOfBirth "1922-01-28".
- Robert_W._Holley dateOfDeath "1993-02-11".
- Robert_W._Holley deathDate "1993-02-11".
- Robert_W._Holley deathPlace Los_Gatos,_California.
- Robert_W._Holley field Biochemistry.
- Robert_W._Holley hasPhotoCollection Robert_W._Holley.
- Robert_W._Holley knownFor Transfer_RNA.
- Robert_W._Holley name "Holley, Robert W.".
- Robert_W._Holley name "Robert W. Holley".
- Robert_W._Holley nationality "American".
- Robert_W._Holley placeOfBirth Urbana,_Illinois.
- Robert_W._Holley placeOfDeath Los_Gatos,_California.
- Robert_W._Holley shortDescription "American biochemist".
- Robert_W._Holley wikiPageUsesTemplate Template:Authority_control.
- Robert_W._Holley wikiPageUsesTemplate Template:Infobox_scientist.
- Robert_W._Holley wikiPageUsesTemplate Template:Nobel_Prize_in_Physiology_or_Medicine_Laureates_1951-1975.
- Robert_W._Holley wikiPageUsesTemplate Template:Persondata.
- Robert_W._Holley wikiPageUsesTemplate Template:Reflist.
- Robert_W._Holley workInstitutions Salk_Institute_for_Biological_Studies.
- Robert_W._Holley description "American biochemist".
- Robert_W._Holley description "American biochemist".
- Robert_W._Holley subject Category:1922_births.