Matches in DBpedia 2015-10 for { <http://dbpedia.org/resource/Richard_D._Wood> ?p ?o }
- Richard_D._Wood abstract "Richard D. Wood (born June 3, 1955, Boulder, Colorado) is an American molecular biologist specializing in research on DNA repair and mutation[1]. He is known for pioneering studies on nucleotide excision repair (NER), particularly for reconstituting the minimum set of proteins involved in this process, identifying proliferating cell nuclear antigen (PCNA) as part of the NER complex [2] and identifying mammalian repair polymerases [3][4]. In humans, mutations affecting the NER DNA repair pathway cause the disease xeroderma pigmentosum or XP. Normal UV and sunlight exposure generates DNA mutations (particularly pyrimidine dimers) in epidermal cells that must be continually repaired through NER. XP patients are particularly sensitive to sun exposure and generally must stay indoors during the day, using heavy sunscreens to prevent skin damage and susceptibility to skin cancer. NER occurs through a programmed set of steps that includes recognition of the damaged site (probably by sensing an unpaired bubble at the mutation site), nicking the DNA at upstream and downstream sites, excising the damaged DNA, then filling in the single-stranded DNA gap using a polymerase, with the opposite strand serving as a template for the proper sequence for the repair patch. Since multiple proteins are involved in NER, different XP patients may have different gene mutations. Cells having different NER gene mutations can complement each other, when the cells are fused together, to reestablish DNA repair since one cell line has an intact enzyme that is defective or missing in the other cell line. Thus, XP can be divided into complementation groups based on which enzyme is defective in the NER pathway [5]. Wood and his colleagues reconstituted purified protein components based on the known defective enzymes from defined XP complementation groups to perform NER in vitro and define DNA repair at the molecular level [6][7]. Wood received his B.S. degree in Biology from Westminster College, Salt Lake City Utah (1975), his Ph.D. degree in Biophysics at the University of California, Berkeley (1977), and was a postdoctoral fellow at Yale University from 1982 to 1985. He performed much of his work on NER at the Imperial Cancer Research Fund, from 1985 to 2001 as postdoctoral fellow, Research Scientist, Senior Scientist, and Principal Scientist. He currently holds the Grady F. Saunders Distinguished Professorship in Molecular Biology in the Department of Carcinogenesis at the University of Texas MD Anderson Cancer Center (Science Park Research Division) in Smithville, Texas [8]. Wood is a jazz bassist (he was a music minor at Westminster College where his roommate at the time was the composer and orchestrator Geoff Stradling) and plays in local bands and together with his wife Enid Wood, a violinist, teacher and artist [9].".
- Richard_D._Wood birthDate "1955-06-03".
- Richard_D._Wood birthYear "1955".
- Richard_D._Wood wikiPageExternalLink wood.html.
- Richard_D._Wood wikiPageExternalLink 991.
- Richard_D._Wood wikiPageExternalLink 6117.
- Richard_D._Wood wikiPageExternalLink sciencepark.mdanderson.org.
- Richard_D._Wood wikiPageExternalLink Home.html.
- Richard_D._Wood wikiPageExternalLink Publications.html.
- Richard_D._Wood wikiPageExternalLink 0092-8674(95)90289-9.
- Richard_D._Wood wikiPageExternalLink www.enidwood.com.
- Richard_D._Wood wikiPageExternalLink 32014.
- Richard_D._Wood wikiPageExternalLink picrender.fcgi?artid=453130&blobtype=pdf.
- Richard_D._Wood wikiPageExternalLink science?_ob=ArticleURL&_udi=B6WSN-4C6BNK5-BC&_user=10&_rdoc=1&_fmt=&_orig=search&_sort=d&_docanchor=&view=c&_acct=C000050221&_version=1&_urlVersion=0&_userid=10&md5=e74b8e13e377bccfcd1948f4f423b8f8.
- Richard_D._Wood wikiPageExternalLink 1897.
- Richard_D._Wood wikiPageExternalLink wood.html.
- Richard_D._Wood wikiPageID "9032727".
- Richard_D._Wood wikiPageLength "5035".
- Richard_D._Wood wikiPageOutDegree "39".
- Richard_D._Wood wikiPageRevisionID "677976494".
- Richard_D._Wood wikiPageWikiLink Bachelor_of_Science.
- Richard_D._Wood wikiPageWikiLink Biology.
- Richard_D._Wood wikiPageWikiLink Biophysics.
- Richard_D._Wood wikiPageWikiLink Boulder,_Colorado.
- Richard_D._Wood wikiPageWikiLink Cancer_Research_UK.
- Richard_D._Wood wikiPageWikiLink Category:1955_births.
- Richard_D._Wood wikiPageWikiLink Category:American_medical_researchers.
- Richard_D._Wood wikiPageWikiLink Category:American_scientists.
- Richard_D._Wood wikiPageWikiLink Category:Fellows_of_the_Royal_Society.
- Richard_D._Wood wikiPageWikiLink Category:Living_people.
- Richard_D._Wood wikiPageWikiLink Category:Molecular_biologists.
- Richard_D._Wood wikiPageWikiLink Category:University_of_California,_Berkeley_alumni.
- Richard_D._Wood wikiPageWikiLink Category:University_of_Pittsburgh_faculty.
- Richard_D._Wood wikiPageWikiLink Category:University_of_Texas_MD_Anderson_Cancer_Center_faculty.
- Richard_D._Wood wikiPageWikiLink Category:Westminster_College_(Utah)_alumni.
- Richard_D._Wood wikiPageWikiLink Category:Yale_University_fellows.
- Richard_D._Wood wikiPageWikiLink Complementation_groups.
- Richard_D._Wood wikiPageWikiLink DNA_repair.
- Richard_D._Wood wikiPageWikiLink Doctor_of_Philosophy.
- Richard_D._Wood wikiPageWikiLink Geoff_Stradling.
- Richard_D._Wood wikiPageWikiLink Imperial_Cancer_Research_Fund.
- Richard_D._Wood wikiPageWikiLink In_vitro.
- Richard_D._Wood wikiPageWikiLink MD_Anderson_Cancer_Center.
- Richard_D._Wood wikiPageWikiLink Meyenburg_Cancer_Research_Prize.
- Richard_D._Wood wikiPageWikiLink Meyenburg_Prize.
- Richard_D._Wood wikiPageWikiLink Mutation.
- Richard_D._Wood wikiPageWikiLink Nucleotide_excision_repair.
- Richard_D._Wood wikiPageWikiLink PCNA.
- Richard_D._Wood wikiPageWikiLink Polymerase.
- Richard_D._Wood wikiPageWikiLink Postdoctoral_fellow.
- Richard_D._Wood wikiPageWikiLink Postdoctoral_researcher.
- Richard_D._Wood wikiPageWikiLink Proliferating_cell_nuclear_antigen.
- Richard_D._Wood wikiPageWikiLink Pyrimidine_dimer.
- Richard_D._Wood wikiPageWikiLink Pyrimidine_dimers.
- Richard_D._Wood wikiPageWikiLink Richard_Cyert.
- Richard_D._Wood wikiPageWikiLink Royal_Society.
- Richard_D._Wood wikiPageWikiLink United_States.
- Richard_D._Wood wikiPageWikiLink University_of_California,_Berkeley.
- Richard_D._Wood wikiPageWikiLink University_of_Pittsburgh.
- Richard_D._Wood wikiPageWikiLink University_of_Texas_MD_Anderson_Cancer_Center.
- Richard_D._Wood wikiPageWikiLink Utah.
- Richard_D._Wood wikiPageWikiLink Westminster_College,_Salt_Lake_City.
- Richard_D._Wood wikiPageWikiLink Westminster_College_(Utah).
- Richard_D._Wood wikiPageWikiLink Xeroderma_pigmentosum.
- Richard_D._Wood wikiPageWikiLink Yale_University.
- Richard_D._Wood wikiPageWikiLinkText "Richard D. Wood".
- Richard_D._Wood wikiPageWikiLinkText "Richard Dean Wood".
- Richard_D._Wood dateOfBirth "1955-06-03".
- Richard_D._Wood hasPhotoCollection Richard_D._Wood.
- Richard_D._Wood name "Wood, Richard D.".
- Richard_D._Wood shortDescription "American molecular biologist".
- Richard_D._Wood wikiPageUsesTemplate Template:No_footnotes.
- Richard_D._Wood wikiPageUsesTemplate Template:Other_people.
- Richard_D._Wood wikiPageUsesTemplate Template:Persondata.
- Richard_D._Wood description "American molecular biologist".
- Richard_D._Wood description "American molecular biologist".
- Richard_D._Wood subject Category:1955_births.
- Richard_D._Wood subject Category:American_medical_researchers.
- Richard_D._Wood subject Category:American_scientists.
- Richard_D._Wood subject Category:Fellows_of_the_Royal_Society.
- Richard_D._Wood subject Category:Living_people.
- Richard_D._Wood subject Category:Molecular_biologists.
- Richard_D._Wood subject Category:University_of_California,_Berkeley_alumni.
- Richard_D._Wood subject Category:University_of_Pittsburgh_faculty.
- Richard_D._Wood subject Category:University_of_Texas_MD_Anderson_Cancer_Center_faculty.
- Richard_D._Wood subject Category:Westminster_College_(Utah)_alumni.
- Richard_D._Wood subject Category:Yale_University_fellows.
- Richard_D._Wood hypernym Biologist.
- Richard_D._Wood type Agent.
- Richard_D._Wood type Article.
- Richard_D._Wood type Biologist.
- Richard_D._Wood type List.
- Richard_D._Wood type Person.
- Richard_D._Wood type Scientist.
- Richard_D._Wood type Article.
- Richard_D._Wood type Biologist.
- Richard_D._Wood type Geneticist.
- Richard_D._Wood type List.
- Richard_D._Wood type Member.
- Richard_D._Wood type Scientist.