Matches in DBpedia 2015-10 for { <http://dbpedia.org/resource/Rho-associated_protein_kinase> ?p ?o }
- Rho-associated_protein_kinase abstract "Rho-associated protein kinase (ROCK) is a kinase belonging to the AGC (PKA/ PKG/PKC) family of serine-threonine kinases. It is involved mainly in regulating the shape and movement of cells by acting on the cytoskeleton.ROCKs (ROCK1 and ROCK2) occur in mammals (human, rat, mouse, cow), zebrafish, Xenopus, invertebrates (C. elegans, Mosquito, Drosophila) and chicken. Human ROCK1 has a molecular mass of 158 kDa and is a major downstream effector of the small GTPase RhoA. Mammalian ROCK consists of a kinase domain, a coiled-coil region and a Pleckstrin homology (PH) domain, which reduces the kinase activity of ROCKs by an autoinhibitory intramolecular fold if RhoA-GTP is not present.Rat ROCKs were discovered as the first effectors of Rho and they induce the formation of stress fibers and focal adhesions by phosphorylating MLC (myosin light chain).Due to this phosphorylation, the actin binding of myosin II and, thus, the contractility increases. Two mouse ROCK isoforms ROCK1 and ROCK2 have been identified. ROCK1 is mainly expressed in the lung, liver, spleen, kidney and testis. However, ROCK2 is distributed mostly in the brain and heart.".
- Rho-associated_protein_kinase arm "p".
- Rho-associated_protein_kinase band "24".
- Rho-associated_protein_kinase ecNumber "2.7.11.1".
- Rho-associated_protein_kinase entrezgene "579202".
- Rho-associated_protein_kinase entrezgene "6093".
- Rho-associated_protein_kinase entrezgene "9475".
- Rho-associated_protein_kinase hgncid "10251".
- Rho-associated_protein_kinase hgncid "10252".
- Rho-associated_protein_kinase locusSupplementaryData "-q32".
- Rho-associated_protein_kinase omim "601702".
- Rho-associated_protein_kinase omim "604002".
- Rho-associated_protein_kinase refseq "NM_004850".
- Rho-associated_protein_kinase refseq "NM_005406".
- Rho-associated_protein_kinase symbol "ROCK1".
- Rho-associated_protein_kinase symbol "ROCK2".
- Rho-associated_protein_kinase symbol "Rho-associated protein kinase".
- Rho-associated_protein_kinase symbol "Rho-associated, coiled-coil-containing protein kinase".
- Rho-associated_protein_kinase thumbnail 3d9v_bio_r_500.jpg?width=300.
- Rho-associated_protein_kinase uniprot "O75116".
- Rho-associated_protein_kinase uniprot "Q13464".
- Rho-associated_protein_kinase wikiPageID "27388475".
- Rho-associated_protein_kinase wikiPageLength "16325".
- Rho-associated_protein_kinase wikiPageOutDegree "75".
- Rho-associated_protein_kinase wikiPageRevisionID "680295174".
- Rho-associated_protein_kinase wikiPageWikiLink ATPase.
- Rho-associated_protein_kinase wikiPageWikiLink Actin.
- Rho-associated_protein_kinase wikiPageWikiLink Activator_(genetics).
- Rho-associated_protein_kinase wikiPageWikiLink Amino_acid.
- Rho-associated_protein_kinase wikiPageWikiLink Amyotrophic_lateral_sclerosis.
- Rho-associated_protein_kinase wikiPageWikiLink Apoptosis.
- Rho-associated_protein_kinase wikiPageWikiLink Arachidonic_acid.
- Rho-associated_protein_kinase wikiPageWikiLink Atomic_mass_unit.
- Rho-associated_protein_kinase wikiPageWikiLink Bleb_(cell_biology).
- Rho-associated_protein_kinase wikiPageWikiLink Brain.
- Rho-associated_protein_kinase wikiPageWikiLink CDC42.
- Rho-associated_protein_kinase wikiPageWikiLink Cancer.
- Rho-associated_protein_kinase wikiPageWikiLink Category:Animal_genes.
- Rho-associated_protein_kinase wikiPageWikiLink Category:Animal_proteins.
- Rho-associated_protein_kinase wikiPageWikiLink Category:Cell_cycle.
- Rho-associated_protein_kinase wikiPageWikiLink Cdc42.
- Rho-associated_protein_kinase wikiPageWikiLink Cell_(biology).
- Rho-associated_protein_kinase wikiPageWikiLink Cell_migration.
- Rho-associated_protein_kinase wikiPageWikiLink Centriole.
- Rho-associated_protein_kinase wikiPageWikiLink Centrioles.
- Rho-associated_protein_kinase wikiPageWikiLink Cofilin.
- Rho-associated_protein_kinase wikiPageWikiLink Coiled-coil.
- Rho-associated_protein_kinase wikiPageWikiLink Coiled_coil.
- Rho-associated_protein_kinase wikiPageWikiLink Collagen.
- Rho-associated_protein_kinase wikiPageWikiLink Contractility.
- Rho-associated_protein_kinase wikiPageWikiLink Cytokinesis.
- Rho-associated_protein_kinase wikiPageWikiLink Cytoskeleton.
- Rho-associated_protein_kinase wikiPageWikiLink Diabetes.
- Rho-associated_protein_kinase wikiPageWikiLink Diabetes_mellitus.
- Rho-associated_protein_kinase wikiPageWikiLink Enzyme_inhibitor.
- Rho-associated_protein_kinase wikiPageWikiLink Focal_adhesion.
- Rho-associated_protein_kinase wikiPageWikiLink Focal_adhesions.
- Rho-associated_protein_kinase wikiPageWikiLink GTPase.
- Rho-associated_protein_kinase wikiPageWikiLink Growth_cone.
- Rho-associated_protein_kinase wikiPageWikiLink Heart.
- Rho-associated_protein_kinase wikiPageWikiLink Homology_(biology).
- Rho-associated_protein_kinase wikiPageWikiLink Insulin.
- Rho-associated_protein_kinase wikiPageWikiLink Integrin.
- Rho-associated_protein_kinase wikiPageWikiLink Intramolecular.
- Rho-associated_protein_kinase wikiPageWikiLink Intramolecular_reaction.
- Rho-associated_protein_kinase wikiPageWikiLink Kidney.
- Rho-associated_protein_kinase wikiPageWikiLink Kinase.
- Rho-associated_protein_kinase wikiPageWikiLink LIMK1.
- Rho-associated_protein_kinase wikiPageWikiLink LIM_kinase.
- Rho-associated_protein_kinase wikiPageWikiLink Liver.
- Rho-associated_protein_kinase wikiPageWikiLink Lung.
- Rho-associated_protein_kinase wikiPageWikiLink Membrane_blebbing.
- Rho-associated_protein_kinase wikiPageWikiLink Molecular_mass.
- Rho-associated_protein_kinase wikiPageWikiLink Myosin.
- Rho-associated_protein_kinase wikiPageWikiLink Myosin_II.
- Rho-associated_protein_kinase wikiPageWikiLink Myotonin-protein_kinase.
- Rho-associated_protein_kinase wikiPageWikiLink Neoplasm.
- Rho-associated_protein_kinase wikiPageWikiLink Neurite.
- Rho-associated_protein_kinase wikiPageWikiLink Oligomer.
- Rho-associated_protein_kinase wikiPageWikiLink Oligomerization.
- Rho-associated_protein_kinase wikiPageWikiLink PH_domain.
- Rho-associated_protein_kinase wikiPageWikiLink PTEN_(gene).
- Rho-associated_protein_kinase wikiPageWikiLink Parkinson´s_disease.
- Rho-associated_protein_kinase wikiPageWikiLink Phosphatase.
- Rho-associated_protein_kinase wikiPageWikiLink Phosphorylation.
- Rho-associated_protein_kinase wikiPageWikiLink Pleckstrin_homology.
- Rho-associated_protein_kinase wikiPageWikiLink Pleckstrin_homology_domain.
- Rho-associated_protein_kinase wikiPageWikiLink Pulmonary_hypertension.
- Rho-associated_protein_kinase wikiPageWikiLink RHOA.
- Rho-associated_protein_kinase wikiPageWikiLink ROCK1.
- Rho-associated_protein_kinase wikiPageWikiLink RhoA.
- Rho-associated_protein_kinase wikiPageWikiLink Rho_factor.
- Rho-associated_protein_kinase wikiPageWikiLink Rho_family_of_GTPases.
- Rho-associated_protein_kinase wikiPageWikiLink Sequence_motif.
- Rho-associated_protein_kinase wikiPageWikiLink threonine-specific_protein_kinase.
- Rho-associated_protein_kinase wikiPageWikiLink Spleen.
- Rho-associated_protein_kinase wikiPageWikiLink Stress_fiber.
- Rho-associated_protein_kinase wikiPageWikiLink Testicle.
- Rho-associated_protein_kinase wikiPageWikiLink Testis.
- Rho-associated_protein_kinase wikiPageWikiLink Tumor.