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- RIGVIR abstract "RIGVIR is a virotherapy medication approved by the State Agency of Medicines of the Republic of Latvia. It was developed in the 1960s and 1970s by the team of Aina Muceniece (1924-2010) and patented in 2002.Rigvir is a drug that contains live, natural virus, which has cytolytic and immunomodulating effects. Cytolytic action – finding and destroying malignant cells, applies only to the cancer cells without affecting the normal tissue cells.Regarding immunomodulation, because of its structure Rigvir selectively affects cells in sensitive tumors. Rigvir activates cells of the immune system due to what causes specific immune response against itself. It is not genetically modified and not pathogenic virus, it is not able to replicate in human body. It is issued in oncology for the prevention of secondary immunodeficiency. In 2015 RIGVIR was registered in Georgia and included in the Latvian national guidelines for skin cancer and melanoma treatment.Recent retrospective study published in Melanoma Research showed that IB-IIC melanoma patients treated with oncolytic virus Rigvir were 4.39–6.57-fold lower mortality than those, who according to melanoma treatment guidelines did not receive virotherapy and were only observed.Passed all phases of clinical trials and registered in Latvia (Reg. No.: 04-0229) and is used as a prescription drug for the treatment of cancer. Rigvir – 7 strain ECHO-virus, a solution for intramuscular injection. Code: ATX: L03AX. Must be stored and transported at a temperature of -20°C ± 2°C.".
- RIGVIR thumbnail Virions_of_enteroviruses_in_Rigvir.jpg?width=300.
- RIGVIR wikiPageExternalLink latvian_virotherapy_center_en.html.
- RIGVIR wikiPageID "38685110".
- RIGVIR wikiPageLength "7084".
- RIGVIR wikiPageOutDegree "11".
- RIGVIR wikiPageRevisionID "683314763".
- RIGVIR wikiPageWikiLink Aina_Muceniece.
- RIGVIR wikiPageWikiLink Category:Experimental_cancer_treatments.
- RIGVIR wikiPageWikiLink Category:Immunomodulating_drugs.
- RIGVIR wikiPageWikiLink Category:Latvian_inventions.
- RIGVIR wikiPageWikiLink Category:Research_in_Latvia.
- RIGVIR wikiPageWikiLink Category:Virotherapy.
- RIGVIR wikiPageWikiLink Oncolytic_virus.
- RIGVIR wikiPageWikiLink State_Agency_of_Medicines_of_the_Republic_of_Latvia.
- RIGVIR wikiPageWikiLink Virotherapy.
- RIGVIR wikiPageWikiLink File:Rigvir_antigen_in_tumor_cells.jpg.
- RIGVIR wikiPageWikiLink File:Virions_of_enteroviruses_in_Rigvir.jpg.
- RIGVIR wikiPageWikiLinkText "RIGVIR".
- RIGVIR wikiPageWikiLinkText "Rigvir".
- RIGVIR hasPhotoCollection RIGVIR.
- RIGVIR wikiPageUsesTemplate Template:Medref.
- RIGVIR wikiPageUsesTemplate Template:Reflist.
- RIGVIR subject Category:Experimental_cancer_treatments.
- RIGVIR subject Category:Immunomodulating_drugs.
- RIGVIR subject Category:Latvian_inventions.
- RIGVIR subject Category:Research_in_Latvia.
- RIGVIR subject Category:Virotherapy.
- RIGVIR hypernym Medication.
- RIGVIR type Drug.
- RIGVIR type Drug.
- RIGVIR type Thing.
- RIGVIR comment "RIGVIR is a virotherapy medication approved by the State Agency of Medicines of the Republic of Latvia. It was developed in the 1960s and 1970s by the team of Aina Muceniece (1924-2010) and patented in 2002.Rigvir is a drug that contains live, natural virus, which has cytolytic and immunomodulating effects.".
- RIGVIR label "RIGVIR".
- RIGVIR sameAs m.0rfgf3s.
- RIGVIR sameAs Q7276779.
- RIGVIR sameAs Q7276779.
- RIGVIR wasDerivedFrom RIGVIR?oldid=683314763.
- RIGVIR depiction Virions_of_enteroviruses_in_Rigvir.jpg.
- RIGVIR isPrimaryTopicOf RIGVIR.