Matches in DBpedia 2015-10 for { <http://dbpedia.org/resource/RAS_p21_protein_activator_1> ?p ?o }
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- RAS_p21_protein_activator_1 abstract "RAS p21 protein activator 1 or RasGAP (Ras GTPase activating protein), also known as RASA1, is a 120-kDa cytosolic human protein that provides two principal activities: Inactivation of Ras from its active GTP-bound form to its inactive GDP-bound form by enhancing the endogenous GTPase activity of Ras, via its C-terminal GAP domain Mitogenic signal transmission towards downstream interacting partners through its N-terminal SH2-SH3-SH2 domainsThe protein encoded by this gene is located in the cytoplasm and is part of the GAP1 family of GTPase-activating proteins. The gene product stimulates the GTPase activity of normal RAS p21 but not its oncogenic counterpart. Acting as a suppressor of RAS function, the protein enhances the weak intrinsic GTPase activity of RAS proteins resulting in the inactive GDP-bound form of RAS, thereby allowing control of cellular proliferation and differentiation. Mutations leading to changes in the binding sites of either protein are associated with basal cell carcinomas. Alternative splicing results in two isoforms where the shorter isoform, lacking the N-terminal hydrophobic region but retaining the same activity, appears to be abundantly expressed in placental but not adult tissues.".
- RAS_p21_protein_activator_1 entrezgene "5921".
- RAS_p21_protein_activator_1 wikiPageExternalLink RASA1_welcome.php.
- RAS_p21_protein_activator_1 wikiPageExternalLink NBK52764.
- RAS_p21_protein_activator_1 wikiPageExternalLink 608355,187260,187300,185300,149000,138000,139150,608354,608355,139150,608354,608355.
- RAS_p21_protein_activator_1 wikiPageID "14116882".
- RAS_p21_protein_activator_1 wikiPageLength "13874".
- RAS_p21_protein_activator_1 wikiPageOutDegree "29".
- RAS_p21_protein_activator_1 wikiPageRevisionID "679029085".
- RAS_p21_protein_activator_1 wikiPageWikiLink ANXA6.
- RAS_p21_protein_activator_1 wikiPageWikiLink Atomic_mass_unit.
- RAS_p21_protein_activator_1 wikiPageWikiLink Category:Proteins.
- RAS_p21_protein_activator_1 wikiPageWikiLink Caveolin_2.
- RAS_p21_protein_activator_1 wikiPageWikiLink DNAJA3.
- RAS_p21_protein_activator_1 wikiPageWikiLink DOK1.
- RAS_p21_protein_activator_1 wikiPageWikiLink EPHB3.
- RAS_p21_protein_activator_1 wikiPageWikiLink EPH_receptor_B2.
- RAS_p21_protein_activator_1 wikiPageWikiLink GAP_domain.
- RAS_p21_protein_activator_1 wikiPageWikiLink GNB2L1.
- RAS_p21_protein_activator_1 wikiPageWikiLink GTPase.
- RAS_p21_protein_activator_1 wikiPageWikiLink Guanosine_diphosphate.
- RAS_p21_protein_activator_1 wikiPageWikiLink Guanosine_triphosphate.
- RAS_p21_protein_activator_1 wikiPageWikiLink HCK.
- RAS_p21_protein_activator_1 wikiPageWikiLink HRAS.
- RAS_p21_protein_activator_1 wikiPageWikiLink Huntingtin.
- RAS_p21_protein_activator_1 wikiPageWikiLink Insulin-like_growth_factor_1_receptor.
- RAS_p21_protein_activator_1 wikiPageWikiLink KDa.
- RAS_p21_protein_activator_1 wikiPageWikiLink KHDRBS1.
- RAS_p21_protein_activator_1 wikiPageWikiLink MiR-132.
- RAS_p21_protein_activator_1 wikiPageWikiLink Mir-132_microRNA.
- RAS_p21_protein_activator_1 wikiPageWikiLink NCK1.
- RAS_p21_protein_activator_1 wikiPageWikiLink PDGFRB.
- RAS_p21_protein_activator_1 wikiPageWikiLink PH_domain.
- RAS_p21_protein_activator_1 wikiPageWikiLink PTK2B.
- RAS_p21_protein_activator_1 wikiPageWikiLink Pleckstrin_homology_domain.
- RAS_p21_protein_activator_1 wikiPageWikiLink Protein-protein_interaction.
- RAS_p21_protein_activator_1 wikiPageWikiLink Protein–protein_interaction.
- RAS_p21_protein_activator_1 wikiPageWikiLink Proto-oncogene_tyrosine-protein_kinase_Src.
- RAS_p21_protein_activator_1 wikiPageWikiLink Ras_(protein).
- RAS_p21_protein_activator_1 wikiPageWikiLink Ras_subfamily.
- RAS_p21_protein_activator_1 wikiPageWikiLink SH2_domain.
- RAS_p21_protein_activator_1 wikiPageWikiLink SH3_domain.
- RAS_p21_protein_activator_1 wikiPageWikiLink SOCS3.
- RAS_p21_protein_activator_1 wikiPageWikiLink Src_(gene).
- RAS_p21_protein_activator_1 wikiPageWikiLinkText "RAS p21 protein activator 1".
- RAS_p21_protein_activator_1 wikiPageWikiLinkText "RASA1".
- RAS_p21_protein_activator_1 wikiPageWikiLinkText "p120RasGAP".
- RAS_p21_protein_activator_1 hasPhotoCollection RAS_p21_protein_activator_1.
- RAS_p21_protein_activator_1 requireManualInspection "no".
- RAS_p21_protein_activator_1 summaryText "The protein encoded by this gene is located in the cytoplasm and is part of the GAP1 family of GTPase-activating proteins. The gene product stimulates the GTPase activity of normal RAS p21 but not its oncogenic counterpart. Acting as a suppressor of RAS function, the protein enhances the weak intrinsic GTPase activity of RAS proteins resulting in the inactive GDP-bound form of RAS, thereby allowing control of cellular proliferation and differentiation. Mutations leading to changes in the binding sites of either protein are associated with basal cell carcinomas. Alternative splicing results in two isoforms where the shorter isoform, lacking the N-terminal hydrophobic region but retaining the same activity, appears to be abundantly expressed in placental but not adult tissues.".
- RAS_p21_protein_activator_1 updateCitations "yes".
- RAS_p21_protein_activator_1 updatePage "yes".
- RAS_p21_protein_activator_1 updateProteinBox "yes".
- RAS_p21_protein_activator_1 updateSummary "yes".
- RAS_p21_protein_activator_1 wikiPageUsesTemplate Template:Div_col.
- RAS_p21_protein_activator_1 wikiPageUsesTemplate Template:Div_col_end.
- RAS_p21_protein_activator_1 wikiPageUsesTemplate Template:GTP-binding_protein_regulators.
- RAS_p21_protein_activator_1 wikiPageUsesTemplate Template:Gene-5-stub.
- RAS_p21_protein_activator_1 wikiPageUsesTemplate Template:PBB.
- RAS_p21_protein_activator_1 wikiPageUsesTemplate Template:PBB_Controls.
- RAS_p21_protein_activator_1 wikiPageUsesTemplate Template:PBB_Further_reading.
- RAS_p21_protein_activator_1 wikiPageUsesTemplate Template:PBB_Summary.
- RAS_p21_protein_activator_1 wikiPageUsesTemplate Template:PDB_Gallery.
- RAS_p21_protein_activator_1 wikiPageUsesTemplate Template:Refbegin.
- RAS_p21_protein_activator_1 wikiPageUsesTemplate Template:Refend.
- RAS_p21_protein_activator_1 wikiPageUsesTemplate Template:Reflist.
- RAS_p21_protein_activator_1 subject Category:Proteins.
- RAS_p21_protein_activator_1 hypernym Part.
- RAS_p21_protein_activator_1 type Biomolecule.
- RAS_p21_protein_activator_1 type Protein.
- RAS_p21_protein_activator_1 type Biomolecule.
- RAS_p21_protein_activator_1 type Nutrient.
- RAS_p21_protein_activator_1 type Thing.
- RAS_p21_protein_activator_1 type Q206229.
- RAS_p21_protein_activator_1 type Q8054.
- RAS_p21_protein_activator_1 comment "RAS p21 protein activator 1 or RasGAP (Ras GTPase activating protein), also known as RASA1, is a 120-kDa cytosolic human protein that provides two principal activities: Inactivation of Ras from its active GTP-bound form to its inactive GDP-bound form by enhancing the endogenous GTPase activity of Ras, via its C-terminal GAP domain Mitogenic signal transmission towards downstream interacting partners through its N-terminal SH2-SH3-SH2 domainsThe protein encoded by this gene is located in the cytoplasm and is part of the GAP1 family of GTPase-activating proteins. ".
- RAS_p21_protein_activator_1 label "RAS p21 protein activator 1".
- RAS_p21_protein_activator_1 sameAs m.03cv408.
- RAS_p21_protein_activator_1 sameAs RAS_p21_proteinski_aktivator_1.
- RAS_p21_protein_activator_1 sameAs RAS_p21_proteinski_aktivator_1.
- RAS_p21_protein_activator_1 sameAs Q7275843.
- RAS_p21_protein_activator_1 sameAs Q7275843.
- RAS_p21_protein_activator_1 wasDerivedFrom RAS_p21_protein_activator_1?oldid=679029085.
- RAS_p21_protein_activator_1 isPrimaryTopicOf RAS_p21_protein_activator_1.