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- Proteolipid_protein_1 abstract "Proteolipid protein 1 is a protein associated with Pelizaeus-Merzbacher disease. It is a 4 transmembrane domain protein which is proposed to bind other copies of itself on the extracellular side of the membrane. In a myelin sheath, as the layers of myelin wraps come together, PLP will bind itself and tightly hold the cellular membranes together.This gene encodes a transmembrane proteolipid protein that is the predominant myelin protein present in the central nervous system (CNS). The encoded protein functions in myelination. This protein may play a role in the compaction, stabilization, and maintenance of myelin sheaths, as well as in oligodendrocyte development and axonal survival. Mutations associated with this gene cause X-linked Pelizaeus-Merzbacher disease and spastic paraplegia type 2. Two transcript variants encoding distinct isoforms have been identified for this gene.In melanocytic cells PLP1 gene expression may be regulated by MITF.".
- Proteolipid_protein_1 entrezgene "5354".
- Proteolipid_protein_1 wikiPageExternalLink br.fcgi?book=gene&part=pmd.
- Proteolipid_protein_1 wikiPageID "10147604".
- Proteolipid_protein_1 wikiPageLength "9547".
- Proteolipid_protein_1 wikiPageOutDegree "5".
- Proteolipid_protein_1 wikiPageRevisionID "679021921".
- Proteolipid_protein_1 wikiPageWikiLink Microphthalmia-associated_transcription_factor.
- Proteolipid_protein_1 wikiPageWikiLink Myelin.
- Proteolipid_protein_1 wikiPageWikiLink Myelin_basic_protein.
- Proteolipid_protein_1 wikiPageWikiLink Pelizaeus-Merzbacher_disease.
- Proteolipid_protein_1 wikiPageWikiLink Pelizaeus–Merzbacher_disease.
- Proteolipid_protein_1 wikiPageWikiLink Protein-protein_interaction.
- Proteolipid_protein_1 wikiPageWikiLink Protein–protein_interaction.
- Proteolipid_protein_1 wikiPageWikiLinkText "PLP1".
- Proteolipid_protein_1 wikiPageWikiLinkText "Proteolipid protein 1".
- Proteolipid_protein_1 wikiPageWikiLinkText "proteolipid protein 1".
- Proteolipid_protein_1 hasPhotoCollection Proteolipid_protein_1.
- Proteolipid_protein_1 requireManualInspection "no".
- Proteolipid_protein_1 summaryText "This gene encodes a transmembrane proteolipid protein that is the predominant myelin protein present in the central nervous system . The encoded protein functions in myelination. This protein may play a role in the compaction, stabilization, and maintenance of myelin sheaths, as well as in oligodendrocyte development and axonal survival. Mutations associated with this gene cause X-linked Pelizaeus-Merzbacher disease and spastic paraplegia type 2. Two transcript variants encoding distinct isoforms have been identified for this gene. In melanocytic cells PLP1 gene expression may be regulated by MITF.".
- Proteolipid_protein_1 updateCitations "yes".
- Proteolipid_protein_1 updatePage "yes".
- Proteolipid_protein_1 updateProteinBox "yes".
- Proteolipid_protein_1 updateSummary "yes".
- Proteolipid_protein_1 wikiPageUsesTemplate Template:Biochemistry-stub.
- Proteolipid_protein_1 wikiPageUsesTemplate Template:Cell_membrane_proteins.
- Proteolipid_protein_1 wikiPageUsesTemplate Template:MeshName.
- Proteolipid_protein_1 wikiPageUsesTemplate Template:PBB.
- Proteolipid_protein_1 wikiPageUsesTemplate Template:PBB_Controls.
- Proteolipid_protein_1 wikiPageUsesTemplate Template:PBB_Further_reading.
- Proteolipid_protein_1 wikiPageUsesTemplate Template:PBB_Summary.
- Proteolipid_protein_1 wikiPageUsesTemplate Template:Refbegin.
- Proteolipid_protein_1 wikiPageUsesTemplate Template:Refend.
- Proteolipid_protein_1 wikiPageUsesTemplate Template:Reflist.
- Proteolipid_protein_1 hypernym Protein.
- Proteolipid_protein_1 type Biomolecule.
- Proteolipid_protein_1 type Protein.
- Proteolipid_protein_1 type Thing.
- Proteolipid_protein_1 type Q206229.
- Proteolipid_protein_1 type Q8054.
- Proteolipid_protein_1 comment "Proteolipid protein 1 is a protein associated with Pelizaeus-Merzbacher disease. It is a 4 transmembrane domain protein which is proposed to bind other copies of itself on the extracellular side of the membrane. In a myelin sheath, as the layers of myelin wraps come together, PLP will bind itself and tightly hold the cellular membranes together.This gene encodes a transmembrane proteolipid protein that is the predominant myelin protein present in the central nervous system (CNS).".
- Proteolipid_protein_1 label "Proteolipid protein 1".
- Proteolipid_protein_1 sameAs Proteolipid-Protein.
- Proteolipid_protein_1 sameAs PLP1_(Gène).
- Proteolipid_protein_1 sameAs m.02q3cf3.
- Proteolipid_protein_1 sameAs Q205986.
- Proteolipid_protein_1 sameAs Q205986.
- Proteolipid_protein_1 wasDerivedFrom Proteolipid_protein_1?oldid=679021921.
- Proteolipid_protein_1 isPrimaryTopicOf Proteolipid_protein_1.