Matches in DBpedia 2015-10 for { <http://dbpedia.org/resource/Prosensa> ?p ?o }
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- Prosensa abstract "Prosensa is a biotechnology company engaged in the discovery, development and commercialization of RNA-modulating therapeutics. The company targets genetic disorders with a large unmet medical need, with a primary focus on neuromuscular and neurodegenerative disorders such as Duchenne Muscular Dystrophy (DMD), Myotonic Dystrophy and Huntington's disease.Prosensa's portfolio of clinical and pre-clinical RNA-based drug candidates is currently focused on the treatment of DMD. Prosensa’s lead product, drisapersen, has completed Phase III clinical trials and a New Drug Application (NDA) has been submitted to the Food and Drug Administration (FDA). Three additional products, PRO044, PRO045 and PRO053 are in clinical development, and PRO052 and PRO055 are in advanced preclinical development. In parallel, Prosensa has also advanced program called PROSPECT into pre-clinical testing, which includes a new and innovative application of its exon-skipping technology platform, applying multiple exon skipping, to specifically target rarer mutations (initially in exon 10 to 30 region) in the dystrophin gene. This approach could have applicability between 5-13% of the DMD population.In addition to its clinical trials, Prosensa is running a Natural History Study, which has completed enrollment with 269 patients across the US, Europe and Latin America. The purpose of this study is to characterize the natural history and progression of DMD, to help inform the design of future studies, to capture biomarkers of safety and disease progression and to provide comparative data for the development of rare exons for which formal controlled trials are not feasible.Prosensa commenced operations in 2002 and is located in Leiden, The Netherlands. The company works closely together with academia, patient groups and experts worldwide. Prosensa entered into an exclusive licensing agreement in 2003 with Leiden University Medical Center (LUMC) for their proprietary RNA modulation exon-skipping technology to develop treatments for DMD, other neuromuscular disorders and indications outside the field of neuromuscular disorders.In November 2014, BioMarin Pharmaceutical agreed to pay up to $840 million to acquire Prosensa.".
- Prosensa foundingYear "2002".
- Prosensa industry Biotechnology.
- Prosensa internationally "true".
- Prosensa keyPerson Chairman.
- Prosensa keyPerson Chief_Medical_Officer.
- Prosensa keyPerson Chief_business_officer.
- Prosensa keyPerson Chief_executive_officer.
- Prosensa keyPerson Chief_financial_officer.
- Prosensa location Leiden.
- Prosensa location Netherlands.
- Prosensa numberOfEmployees "89".
- Prosensa product Drug.
- Prosensa type Public_company.
- Prosensa wikiPageExternalLink www.prosensa.eu.
- Prosensa wikiPageID "35472393".
- Prosensa wikiPageLength "3515".
- Prosensa wikiPageOutDegree "25".
- Prosensa wikiPageRevisionID "678413522".
- Prosensa wikiPageWikiLink BioMarin_Pharmaceutical.
- Prosensa wikiPageWikiLink Biotechnology.
- Prosensa wikiPageWikiLink Category:Biotechnology_companies_of_the_Netherlands.
- Prosensa wikiPageWikiLink Category:Companies_listed_on_NASDAQ.
- Prosensa wikiPageWikiLink Chairman.
- Prosensa wikiPageWikiLink Chief_Business_Officer.
- Prosensa wikiPageWikiLink Chief_Executive_Officer.
- Prosensa wikiPageWikiLink Chief_Financial_Officer.
- Prosensa wikiPageWikiLink Chief_Medical_Officer.
- Prosensa wikiPageWikiLink Chief_business_officer.
- Prosensa wikiPageWikiLink Chief_executive_officer.
- Prosensa wikiPageWikiLink Chief_financial_officer.
- Prosensa wikiPageWikiLink Drisapersen.
- Prosensa wikiPageWikiLink Drug.
- Prosensa wikiPageWikiLink Duchenne_Muscular_Dystrophy.
- Prosensa wikiPageWikiLink Duchenne_muscular_dystrophy.
- Prosensa wikiPageWikiLink Dystrophin.
- Prosensa wikiPageWikiLink Food_and_Drug_Administration.
- Prosensa wikiPageWikiLink Huntingtons_disease.
- Prosensa wikiPageWikiLink Leiden.
- Prosensa wikiPageWikiLink Myotonic_Dystrophy.
- Prosensa wikiPageWikiLink Netherlands.
- Prosensa wikiPageWikiLink New_Drug_Application.
- Prosensa wikiPageWikiLink New_drug_application_(FDA).
- Prosensa wikiPageWikiLink PRO044.
- Prosensa wikiPageWikiLink PRO045.
- Prosensa wikiPageWikiLink PRO052.
- Prosensa wikiPageWikiLink PRO053.
- Prosensa wikiPageWikiLink PRO055.
- Prosensa wikiPageWikiLink Public_company.
- Prosensa wikiPageWikiLinkText "Prosensa".
- Prosensa foundation "2002".
- Prosensa hasPhotoCollection Prosensa.
- Prosensa homepage "www.prosensa.com".
- Prosensa industry Biotechnology.
- Prosensa intl "yes".
- Prosensa keyPeople "Hans Schikan , Berndt Modig , Giles Champion , Luc Dochez David Mott".
- Prosensa location Leiden.
- Prosensa location Netherlands.
- Prosensa name "Prosensa Therapeutics".
- Prosensa numEmployees "89".
- Prosensa products Drug.
- Prosensa type Public_company.
- Prosensa wikiPageUsesTemplate Template:Infobox_company.
- Prosensa wikiPageUsesTemplate Template:Official_website.
- Prosensa wikiPageUsesTemplate Template:Reflist.
- Prosensa subject Category:Biotechnology_companies_of_the_Netherlands.
- Prosensa subject Category:Companies_listed_on_NASDAQ.
- Prosensa hypernym Company.
- Prosensa type Agent.
- Prosensa type Company.
- Prosensa type Organisation.
- Prosensa type Company.
- Prosensa type Organization.
- Prosensa type Agent.
- Prosensa type SocialPerson.
- Prosensa type Thing.
- Prosensa type Q43229.
- Prosensa comment "Prosensa is a biotechnology company engaged in the discovery, development and commercialization of RNA-modulating therapeutics. The company targets genetic disorders with a large unmet medical need, with a primary focus on neuromuscular and neurodegenerative disorders such as Duchenne Muscular Dystrophy (DMD), Myotonic Dystrophy and Huntington's disease.Prosensa's portfolio of clinical and pre-clinical RNA-based drug candidates is currently focused on the treatment of DMD.".
- Prosensa label "Prosensa".
- Prosensa sameAs Prosensa.
- Prosensa sameAs m.0j9m911.
- Prosensa sameAs Q7250583.
- Prosensa sameAs Q7250583.
- Prosensa wasDerivedFrom Prosensa?oldid=678413522.
- Prosensa homepage www.prosensa.com.
- Prosensa isPrimaryTopicOf Prosensa.
- Prosensa name "Prosensa Therapeutics".