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- Pramocaine abstract "Pramocaine (INN and BAN, also known as pramoxine or pramoxine HCI) is a topical anesthetic discovered at Abbott Laboratories in 1953 and used as an antipruritic. Chemically, it is p-n butoxyphenyl gammamorpholinopropyl ether hydrochloride. During research and development, pramoxine hydrochloride stood out among a series of alkoxy aryl alkamine ethers as an especially good topical local anesthetic agent. Pharmacologic study revealed it to be potent and of low acute and subacute toxicity, well tolerated by most mucous membranes and of a low sensitizing index in man. Like other local anesthetics, paramoxine decreases the permeability of neuronal membranes to sodium ions, blocking both initiation and conduction of nerve impulses. Depolarization and repolarization of excitable neural membranes is thus inhibited, leading to numbness.The popular itch creams Gold Bond and some forms of Calamine Lotion use pramocaine hydrochloride to numb sensitive skin, as does the pain relief variant of Neosporin and some formulations of Sarna. The hydrochloride salt form of pramocaine is water-soluble.".
- Pramocaine atcPrefix "D04".
- Pramocaine atcSuffix "AB07".
- Pramocaine casNumber "140-65-8".
- Pramocaine chEBI "8357".
- Pramocaine fdaUniiCode "068X84E056".
- Pramocaine iupacName "4-[3-(4-butoxyphenoxy)propyl]morpholine".
- Pramocaine pubchem "4886".
- Pramocaine thumbnail Pramoxine.svg?width=300.
- Pramocaine wikiPageID "8981015".
- Pramocaine wikiPageLength "3981".
- Pramocaine wikiPageOutDegree "21".
- Pramocaine wikiPageRevisionID "670770986".
- Pramocaine wikiPageWikiLink Antipruritic.
- Pramocaine wikiPageWikiLink British_Approved_Name.
- Pramocaine wikiPageWikiLink Calamine.
- Pramocaine wikiPageWikiLink Calamine_Lotion.
- Pramocaine wikiPageWikiLink Category:Local_anesthetics.
- Pramocaine wikiPageWikiLink Category:Morpholines.
- Pramocaine wikiPageWikiLink Category:Phenol_ethers.
- Pramocaine wikiPageWikiLink Cinchocaine.
- Pramocaine wikiPageWikiLink Dibucaine.
- Pramocaine wikiPageWikiLink Gold_Bond.
- Pramocaine wikiPageWikiLink Hemorrhoid.
- Pramocaine wikiPageWikiLink Hydrochloride.
- Pramocaine wikiPageWikiLink International_Nonproprietary_Name.
- Pramocaine wikiPageWikiLink Local_anesthesia.
- Pramocaine wikiPageWikiLink Local_anesthetic.
- Pramocaine wikiPageWikiLink Local_anesthetics.
- Pramocaine wikiPageWikiLink Neosporin.
- Pramocaine wikiPageWikiLink Over-the-counter_drug.
- Pramocaine wikiPageWikiLink Poison_ivy.
- Pramocaine wikiPageWikiLink Poison_oak.
- Pramocaine wikiPageWikiLink Poison_sumac.
- Pramocaine wikiPageWikiLink Salt.
- Pramocaine wikiPageWikiLink Sunburn.
- Pramocaine wikiPageWikiLink Topical_anesthetic.
- Pramocaine wikiPageWikiLink Toxicodendron_diversilobum.
- Pramocaine wikiPageWikiLink Toxicodendron_radicans.
- Pramocaine wikiPageWikiLink Toxicodendron_vernix.
- Pramocaine wikiPageWikiLinkText "Pramocaine".
- Pramocaine wikiPageWikiLinkText "Pramocaine/Pramoxine".
- Pramocaine wikiPageWikiLinkText "pramocaine".
- Pramocaine atcPrefix "D04".
- Pramocaine atcSuffix "AB07".
- Pramocaine c "17".
- Pramocaine casNumber "140".
- Pramocaine chebi "8357".
- Pramocaine chembl "1198".
- Pramocaine chemspiderid "4717".
- Pramocaine h "27".
- Pramocaine hasPhotoCollection Pramocaine.
- Pramocaine inchi "1".
- Pramocaine inchikey "DQKXQSGTHWVTAD-UHFFFAOYAU".
- Pramocaine iupacName "4".
- Pramocaine legalCa "OTC".
- Pramocaine legalStatus "OTC/POM".
- Pramocaine legalUk "POM".
- Pramocaine medlineplus "a682429".
- Pramocaine molecularWeight "293.401".
- Pramocaine n "1".
- Pramocaine o "3".
- Pramocaine pubchem "4886".
- Pramocaine routesOfAdministration "Topical, rectal, Vaginal".
- Pramocaine smiles "OCCCC".
- Pramocaine stdinchi "1".
- Pramocaine stdinchikey "DQKXQSGTHWVTAD-UHFFFAOYSA-N".
- Pramocaine unii "68".
- Pramocaine verifiedfields "changed".
- Pramocaine verifiedrevid "464213174".
- Pramocaine wikiPageUsesTemplate Template:Antipruritics.
- Pramocaine wikiPageUsesTemplate Template:Drugbox.
- Pramocaine wikiPageUsesTemplate Template:Reflist.
- Pramocaine wikiPageUsesTemplate Template:Use_mdy_dates.
- Pramocaine wikiPageUsesTemplate Template:Vasoprotectives.
- Pramocaine subject Category:Local_anesthetics.
- Pramocaine subject Category:Morpholines.
- Pramocaine subject Category:Phenol_ethers.
- Pramocaine type ChemicalSubstance.
- Pramocaine type Drug.
- Pramocaine type Anesthetic.
- Pramocaine type Chemical.
- Pramocaine type Ether.
- Pramocaine type Heterocycle.
- Pramocaine type ChemicalObject.
- Pramocaine type Thing.
- Pramocaine type Q8386.
- Pramocaine comment "Pramocaine (INN and BAN, also known as pramoxine or pramoxine HCI) is a topical anesthetic discovered at Abbott Laboratories in 1953 and used as an antipruritic. Chemically, it is p-n butoxyphenyl gammamorpholinopropyl ether hydrochloride. During research and development, pramoxine hydrochloride stood out among a series of alkoxy aryl alkamine ethers as an especially good topical local anesthetic agent.".
- Pramocaine label "Pramocaine".
- Pramocaine sameAs Pramokain.
- Pramocaine sameAs Pramocaïne.
- Pramocaine sameAs m.027s40z.
- Pramocaine sameAs Pramokain.
- Pramocaine sameAs Pramokain.
- Pramocaine sameAs Q1240076.
- Pramocaine sameAs Q1240076.
- Pramocaine wasDerivedFrom Pramocaine?oldid=670770986.
- Pramocaine depiction Pramoxine.svg.
- Pramocaine isPrimaryTopicOf Pramocaine.
