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- Polycap abstract "Polycap is a specific five-in-one fixed dose combination polypill created by Cadila Pharmaceuticals Limited of Ahmedabad, India that combines moderate levels of five different medications in a single, one-a-day pill aimed at reducing/preventing heart attacks and strokes. Photographs of the actual Polycap capsule are available at http://cadilapharma.com/wp-content/uploads/2014/02/Polycap-Corel12.pnghttps://commons.wikimedia.org/wiki/File:Dr_Arun_Maseeh_of_Cadila_Pharmaceuticals_holding_Polycap.JPG A prominent 2009 study found that this pill's combination of three blood pressure medications, a cholesterol reducer, and aspirin had cut the risk of heart attack and stroke in half, with no more adverse effects than taking the components separately.Many different fixed dose combination (FDC) polypills have been proposed, and one for reducing cardiovascular risk was especially sought. While there are benefits to reducing the number of pills that patients have to take (alleviating the so-called "pill burden"), FDC polypills (like Polycap) also raise concerns that any particular mass-produced combination of drugs and/or dosages is actually optimal for relatively few patients (i.e., offering many patients too little of the medication they need, or components that they don't need at all, while exposing all to the side effects, etc.). This is often accepted by FDC proponents as a worthwhile tradeoff in exchange for the benefits of reducing pill-burden.A hypothesis initially proposed by Wald and Law had recommended a six-drug combination to be taken by patients over age 55 at risk of cardiovascular disease events, which would include three half-dose antihypertensives drugs, aspirin, a statin, and folic acid. After further research showed no improvement in clinical outcomes for patients taking folic acid, it was omitted from Cadila Pharmaceuticals' formulation. As tested, "Polycap" combines 100 milligrams of aspirin, with simvastatin (a generic version of Zocor, the cholesterol-lowering statin; 20 mg) and low doses of three blood pressure medications, atenolol (50 mg), ramipril (5 mg) and thiazide (12.5 mg). And despite containing multiple drugs, the pill has a fairly small size which can facilitate swallowing.".
- Polycap wikiPageExternalLink Polycap-Corel12.png.
- Polycap wikiPageExternalLink NCT00443794.
- Polycap wikiPageExternalLink first-look.html.
- Polycap wikiPageExternalLink www.cadilapharma.com.
- Polycap wikiPageExternalLink fulltext.
- Polycap wikiPageExternalLink www.thelancet.com.
- Polycap wikiPageExternalLink File:Dr_Arun_Maseeh_of_Cadila_Pharmaceuticals_holding_Polycap.JPG.
- Polycap wikiPageID "22222532".
- Polycap wikiPageLength "9927".
- Polycap wikiPageOutDegree "41".
- Polycap wikiPageRevisionID "682281429".
- Polycap wikiPageWikiLink Adverse_effect.
- Polycap wikiPageWikiLink Ahmedabad.
- Polycap wikiPageWikiLink American_College_of_Cardiology.
- Polycap wikiPageWikiLink Antihypertensive.
- Polycap wikiPageWikiLink Antihypertensive_drug.
- Polycap wikiPageWikiLink Aspirin.
- Polycap wikiPageWikiLink Atenolol.
- Polycap wikiPageWikiLink Bangalore.
- Polycap wikiPageWikiLink Bioavailability.
- Polycap wikiPageWikiLink Blood_pressure.
- Polycap wikiPageWikiLink Cardiovascular_disease.
- Polycap wikiPageWikiLink Category:Combination_drugs.
- Polycap wikiPageWikiLink Category:Drugs_acting_on_the_cardiovascular_system.
- Polycap wikiPageWikiLink ClinicalTrials.gov.
- Polycap wikiPageWikiLink Combination_drug.
- Polycap wikiPageWikiLink Diabetes.
- Polycap wikiPageWikiLink Diabetes_mellitus.
- Polycap wikiPageWikiLink Fixed_dose_combination.
- Polycap wikiPageWikiLink Folic_acid.
- Polycap wikiPageWikiLink Food_and_Drug_Administration.
- Polycap wikiPageWikiLink Hamilton,_Ontario.
- Polycap wikiPageWikiLink Hydrochlorothiazide.
- Polycap wikiPageWikiLink Hypercholesterolemia.
- Polycap wikiPageWikiLink Hypertension.
- Polycap wikiPageWikiLink India.
- Polycap wikiPageWikiLink McMaster_University.
- Polycap wikiPageWikiLink Myocardial_infarction.
- Polycap wikiPageWikiLink Obesity.
- Polycap wikiPageWikiLink Pill_burden.
- Polycap wikiPageWikiLink Polypharmacy.
- Polycap wikiPageWikiLink Polypill.
- Polycap wikiPageWikiLink Ramipril.
- Polycap wikiPageWikiLink Simvastatin.
- Polycap wikiPageWikiLink Smoking.
- Polycap wikiPageWikiLink St._Johns_Medical_College.
- Polycap wikiPageWikiLink Statin.
- Polycap wikiPageWikiLink Stroke.
- Polycap wikiPageWikiLink The_Lancet.
- Polycap wikiPageWikiLink Thiazide.
- Polycap wikiPageWikiLink U.S._Food_and_Drug_Administration.
- Polycap wikiPageWikiLinkText "Polycap".
- Polycap hasPhotoCollection Polycap.
- Polycap wikiPageUsesTemplate Template:Doi.
- Polycap wikiPageUsesTemplate Template:Reflist.
- Polycap subject Category:Combination_drugs.
- Polycap subject Category:Drugs_acting_on_the_cardiovascular_system.
- Polycap hypernym Polypill.
- Polycap type Drug.
- Polycap type Drug.
- Polycap comment "Polycap is a specific five-in-one fixed dose combination polypill created by Cadila Pharmaceuticals Limited of Ahmedabad, India that combines moderate levels of five different medications in a single, one-a-day pill aimed at reducing/preventing heart attacks and strokes.".
- Polycap label "Polycap".
- Polycap sameAs m.05q6d_v.
- Polycap sameAs Q7226179.
- Polycap sameAs Q7226179.
- Polycap wasDerivedFrom Polycap?oldid=682281429.
- Polycap isPrimaryTopicOf Polycap.