Matches in DBpedia 2015-10 for { <http://dbpedia.org/resource/Platelet> ?p ?o }
- Platelet abstract "Platelets, also called thrombocytes, are a component of blood whose function (along with the coagulation factors) is to stop bleeding by clumping and clogging blood vessel injuries. Platelets have no cell nucleus: they are fragments of cytoplasm which are derived from the megakaryocytes of the bone marrow, and then enter the circulation. These unactivated platelets are biconvex discoid (lens-shaped) structures, 2–3 µm in greatest diameter. Platelets are found only in mammals, whereas in other animals (e.g. birds, amphibians) thrombocytes circulate as intact mononuclear cells.On a stained blood smear, platelets appear as dark purple spots, about 20% the diameter of red blood cells. The smear is used to examine platelets for size, shape, qualitative number, and clumping. The ratio of platelets to red blood cells in a healthy adult is 1:10 to 1:20. The main function of platelets is to contribute to hemostasis: the process of stopping bleeding at the site of interrupted endothelium. They gather at the site and unless the interruption is physically too large, they plug the hole. First, platelets attach to substances outside the interrupted endothelium: adhesion. Second, they change shape, turn on receptors and secrete chemical messengers: activation. Third, they connect to each other through receptor bridges: aggregation. Formation of this platelet plug (primary hemostasis) is associated with activation of the coagulation cascade with resultant fibrin deposition and linking (secondary hemostasis). These processes may overlap: the spectrum is from a predominantly platelet plug, or "white clot" to a predominantly fibrin clot, or "red clot" or the more typical mixture. The final result is the clot. Some would add the subsequent clot retraction and platelet inhibition as fourth and fifth steps to the completion of the process and still others a sixth step wound repair.Low platelet concentration is thrombocytopenia and is due to either decreased production or increased destruction. Elevated platelet concentration is thrombocytosis and is either congenital, reactive (to cytokines), or due to unregulated production: one of the myeloprolerative neoplasms or certain other myeloid neoplasms. A disorder of platelet function is a thrombocytopathy.Normal platelets can respond to an abnormality on the vessel wall rather than to hemorrhage, resulting in inappropriate platelet adhesion/activation and thrombosis: the formation of a clot within an intact vessel. These arise by different mechanisms than a normal clot. Examples are: extending the fibrin clot of venous thrombosis; extending an unstable or ruptured arterial plaque, causing arterial thrombosis; and microcirculatory thrombosis. An arterial thrombus may partially obstruct blood flow, causing downstream ischemia; or completely obstruct it, causing downstream tissue death.".
- Platelet thumbnail Platelets2.JPG?width=300.
- Platelet wikiPageExternalLink 9780123878373.
- Platelet wikiPageID "196121".
- Platelet wikiPageLength "54321".
- Platelet wikiPageOutDegree "213".
- Platelet wikiPageRevisionID "683229654".
- Platelet wikiPageWikiLink Abciximab.
- Platelet wikiPageWikiLink Adenosine_diphosphate.
- Platelet wikiPageWikiLink Adenosine_triphosphate.
- Platelet wikiPageWikiLink Adenylate_cyclase.
- Platelet wikiPageWikiLink Alpha_granule.
- Platelet wikiPageWikiLink Alpha_granules.
- Platelet wikiPageWikiLink Apheresis.
- Platelet wikiPageWikiLink Aplastic_anemia.
- Platelet wikiPageWikiLink Apyrase.
- Platelet wikiPageWikiLink Arterial_thrombosis.
- Platelet wikiPageWikiLink Aspirin.
- Platelet wikiPageWikiLink Aspirin-induced_asthma.
- Platelet wikiPageWikiLink Asthma.
- Platelet wikiPageWikiLink B-thromboglobulin.
- Platelet wikiPageWikiLink B_cell.
- Platelet wikiPageWikiLink B_lymphocyte.
- Platelet wikiPageWikiLink Babesiosis.
- Platelet wikiPageWikiLink Bacteremia.
- Platelet wikiPageWikiLink Bernard-Soulier_syndrome.
- Platelet wikiPageWikiLink Bernard–Soulier_syndrome.
- Platelet wikiPageWikiLink Beta-thromboglobulin.
- Platelet wikiPageWikiLink Birmingham_University.
- Platelet wikiPageWikiLink Blood_bank.
- Platelet wikiPageWikiLink Blood_film.
- Platelet wikiPageWikiLink Blood_smear.
- Platelet wikiPageWikiLink Blood_transfusion.
- Platelet wikiPageWikiLink Bone_marrow.
- Platelet wikiPageWikiLink Buffy_coat.
- Platelet wikiPageWikiLink CD39.
- Platelet wikiPageWikiLink Calcium.
- Platelet wikiPageWikiLink Cancer.
- Platelet wikiPageWikiLink Category:Blood_products.
- Platelet wikiPageWikiLink Category:Cell_biology.
- Platelet wikiPageWikiLink Category:Coagulation_system.
- Platelet wikiPageWikiLink Category:Human_cells.
- Platelet wikiPageWikiLink Category:Transfusion_medicine.
- Platelet wikiPageWikiLink Cell_nucleus.
- Platelet wikiPageWikiLink Centrifuge.
- Platelet wikiPageWikiLink Chemokine.
- Platelet wikiPageWikiLink Chemokines.
- Platelet wikiPageWikiLink Chemotactic.
- Platelet wikiPageWikiLink Chemotaxis.
- Platelet wikiPageWikiLink Chemotherapy.
- Platelet wikiPageWikiLink Cilostazol.
- Platelet wikiPageWikiLink Clopidogrel.
- Platelet wikiPageWikiLink Coagulation.
- Platelet wikiPageWikiLink Coagulation_cascade.
- Platelet wikiPageWikiLink Coagulation_factor.
- Platelet wikiPageWikiLink Coagulation_factors.
- Platelet wikiPageWikiLink Coagulopathy.
- Platelet wikiPageWikiLink Collagen.
- Platelet wikiPageWikiLink Coulter_counter.
- Platelet wikiPageWikiLink Cyclic_AMP.
- Platelet wikiPageWikiLink Cyclic_adenosine_monophosphate.
- Platelet wikiPageWikiLink Cyclooxygenase.
- Platelet wikiPageWikiLink Cytokine.
- Platelet wikiPageWikiLink Cytokines.
- Platelet wikiPageWikiLink Cytoplasm.
- Platelet wikiPageWikiLink Dengue.
- Platelet wikiPageWikiLink Dengue_fever.
- Platelet wikiPageWikiLink Dense_granule.
- Platelet wikiPageWikiLink Dense_granules.
- Platelet wikiPageWikiLink Desmopressin.
- Platelet wikiPageWikiLink Drug-induced_thrombocytopenic_purpura.
- Platelet wikiPageWikiLink ENTPD1.
- Platelet wikiPageWikiLink Ecchymoses.
- Platelet wikiPageWikiLink Ecchymosis.
- Platelet wikiPageWikiLink Efflux_(microbiology).
- Platelet wikiPageWikiLink Eicosanoid.
- Platelet wikiPageWikiLink Electrical_impedance.
- Platelet wikiPageWikiLink Eltrombopag.
- Platelet wikiPageWikiLink Endothelium.
- Platelet wikiPageWikiLink Epidermal_growth_factor.
- Platelet wikiPageWikiLink Epidural.
- Platelet wikiPageWikiLink Epidural_administration.
- Platelet wikiPageWikiLink Eptifibatide.
- Platelet wikiPageWikiLink Essential_thrombocythaemia.
- Platelet wikiPageWikiLink Essential_thrombocytosis.
- Platelet wikiPageWikiLink Extracellular_matrix.
- Platelet wikiPageWikiLink Factor_V.
- Platelet wikiPageWikiLink Factor_VII.
- Platelet wikiPageWikiLink Factor_VIIa.
- Platelet wikiPageWikiLink Factor_XIII.
- Platelet wikiPageWikiLink Fibrin.
- Platelet wikiPageWikiLink Fibrinogen.
- Platelet wikiPageWikiLink Fibroblast_growth_factor.
- Platelet wikiPageWikiLink Fibronectin.
- Platelet wikiPageWikiLink IIIa.
- Platelet wikiPageWikiLink GPVI.
- Platelet wikiPageWikiLink G_protein_coupled_receptors.
- Platelet wikiPageWikiLink G_protein–coupled_receptor.
- Platelet wikiPageWikiLink Gauchers_disease.
- Platelet wikiPageWikiLink George_Gulliver.