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- Plateau_potentials abstract "Plateau potentials, caused by persistent inward currents (PICs), are a type of electrical behaviour seen by cells in the spinal cord. They are of particular importance to spinal motor systems.PICs are set up by the influence of descending monoaminergic reticulospinal pathways. Metabotropic neurotransmitters, via monoaminergic input such as 5-HT and norepinephrine, modulate the activity of dendritic L-type Calcium channels that allow a sustained, positive, inward current into the cell. This leads to a lasting depolarisation. In this state, the cell fires action potentials independent of synaptic input. The PICs can be turned off via the activation of high-frequency inhibitory input at which point the cell returns to a resting state.Plateau potentials are also seen in the cortical, and hippocampal pyramidal neurons. Using iontophoretic, or two-photon glutamate uncaging experiments, it has been discovered that these plateau potentials include activities of voltage dependent calcium channels and NMDA receptors.".
- Plateau_potentials wikiPageID "11204439".
- Plateau_potentials wikiPageLength "1824".
- Plateau_potentials wikiPageOutDegree "8".
- Plateau_potentials wikiPageRevisionID "662964697".
- Plateau_potentials wikiPageWikiLink 5-HT.
- Plateau_potentials wikiPageWikiLink Action_potential.
- Plateau_potentials wikiPageWikiLink Action_potentials.
- Plateau_potentials wikiPageWikiLink Category:Electrophysiology.
- Plateau_potentials wikiPageWikiLink Depolarisation.
- Plateau_potentials wikiPageWikiLink Depolarization.
- Plateau_potentials wikiPageWikiLink Monoaminergic.
- Plateau_potentials wikiPageWikiLink Norepinephrine.
- Plateau_potentials wikiPageWikiLink Reticulospinal.
- Plateau_potentials wikiPageWikiLink Reticulospinal_tract.
- Plateau_potentials wikiPageWikiLink Serotonin.
- Plateau_potentials wikiPageWikiLink Spinal_cord.
- Plateau_potentials wikiPageWikiLinkText "Plateau potentials".
- Plateau_potentials hasPhotoCollection Plateau_potentials.
- Plateau_potentials wikiPageUsesTemplate Template:Neuroscience-stub.
- Plateau_potentials subject Category:Electrophysiology.
- Plateau_potentials hypernym Behaviour.
- Plateau_potentials comment "Plateau potentials, caused by persistent inward currents (PICs), are a type of electrical behaviour seen by cells in the spinal cord. They are of particular importance to spinal motor systems.PICs are set up by the influence of descending monoaminergic reticulospinal pathways. Metabotropic neurotransmitters, via monoaminergic input such as 5-HT and norepinephrine, modulate the activity of dendritic L-type Calcium channels that allow a sustained, positive, inward current into the cell.".
- Plateau_potentials label "Plateau potentials".
- Plateau_potentials sameAs m.02r3lf1.
- Plateau_potentials sameAs Q7202228.
- Plateau_potentials sameAs Q7202228.
- Plateau_potentials wasDerivedFrom Plateau_potentials?oldid=662964697.
- Plateau_potentials isPrimaryTopicOf Plateau_potentials.